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5. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma. Hensel T; Giorgi C; Schmidt O; Calzada-Wack J; Neff F; Buch T; Niggli FK; Schäfer BW; Burdach S; Richter GH Oncotarget; 2016 Jan; 7(2):1451-63. PubMed ID: 26623725 [TBL] [Abstract][Full Text] [Related]
6. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability. He T; Surdez D; Rantala JK; Haapa-Paananen S; Ban J; Kauer M; Tomazou E; Fey V; Alonso J; Kovar H; Delattre O; Iljin K Gene; 2017 Jan; 596():137-146. PubMed ID: 27760381 [TBL] [Abstract][Full Text] [Related]
7. Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein. Theisen ER; Selich-Anderson J; Miller KR; Tanner JM; Taslim C; Pishas KI; Sharma S; Lessnick SL Epigenetics; 2021 Apr; 16(4):405-424. PubMed ID: 32842875 [TBL] [Abstract][Full Text] [Related]
8. Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy. Kovar H Expert Opin Ther Targets; 2014 Nov; 18(11):1315-28. PubMed ID: 25162919 [TBL] [Abstract][Full Text] [Related]
9. Combined analysis of gene expression and genome binding profiles identified potential therapeutic targets of ciclopirox in Ewing sarcoma. Yuan B; Ji W; Xia H; Li J Mol Med Rep; 2018 Mar; 17(3):4291-4298. PubMed ID: 29328472 [TBL] [Abstract][Full Text] [Related]
10. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue. Gierisch ME; Pfistner F; Lopez-Garcia LA; Harder L; Schäfer BW; Niggli FK J Biol Chem; 2016 Dec; 291(52):26922-26933. PubMed ID: 27875302 [TBL] [Abstract][Full Text] [Related]
11. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1. Giorgi C; Boro A; Rechfeld F; Lopez-Garcia LA; Gierisch ME; Schäfer BW; Niggli FK Oncotarget; 2015 Oct; 6(30):28895-910. PubMed ID: 26336820 [TBL] [Abstract][Full Text] [Related]
12. EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma. Showpnil IA; Selich-Anderson J; Taslim C; Boone MA; Crow JC; Theisen ER; Lessnick SL Nucleic Acids Res; 2022 Sep; 50(17):9814-9837. PubMed ID: 36124657 [TBL] [Abstract][Full Text] [Related]
13. FOXM1 is an oncogenic mediator in Ewing Sarcoma. Christensen L; Joo J; Lee S; Wai D; Triche TJ; May WA PLoS One; 2013; 8(1):e54556. PubMed ID: 23365673 [TBL] [Abstract][Full Text] [Related]
14. Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma. Stegmaier K; Wong JS; Ross KN; Chow KT; Peck D; Wright RD; Lessnick SL; Kung AL; Golub TR PLoS Med; 2007 Apr; 4(4):e122. PubMed ID: 17425403 [TBL] [Abstract][Full Text] [Related]
15. Catalytic inhibition of KDM1A in Ewing sarcoma is insufficient as a therapeutic strategy. Romo-Morales A; Aladowicz E; Blagg J; Gatz SA; Shipley JM Pediatr Blood Cancer; 2019 Sep; 66(9):e27888. PubMed ID: 31207107 [TBL] [Abstract][Full Text] [Related]
17. EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth. Issaq SH; Mendoza A; Kidner R; Rosales TI; Duveau DY; Heske CM; Rohde JM; Boxer MB; Thomas CJ; DeBerardinis RJ; Helman LJ Mol Cancer Ther; 2020 Jul; 19(7):1520-1529. PubMed ID: 32371575 [TBL] [Abstract][Full Text] [Related]
18. EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance. Robin TP; Smith A; McKinsey E; Reaves L; Jedlicka P; Ford HL Mol Cancer Res; 2012 Aug; 10(8):1098-108. PubMed ID: 22723308 [TBL] [Abstract][Full Text] [Related]
19. EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma. Shimizu R; Tanaka M; Tsutsumi S; Aburatani H; Yamazaki Y; Homme M; Kitagawa Y; Nakamura T Cancer Sci; 2018 Sep; 109(9):2907-2918. PubMed ID: 29945296 [TBL] [Abstract][Full Text] [Related]
20. EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphology. Zhou Z; Yu L; Kleinerman ES Cancer; 2014 Feb; 120(4):579-88. PubMed ID: 24415532 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]