212 related articles for article (PubMed ID: 35299278)
1. Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme.
Rajabi N; Hansen TN; Nielsen AL; Nguyen HT; Baek M; Bolding JE; Bahlke OØ; Petersen SEG; Bartling CRO; Strømgaard K; Olsen CA
Angew Chem Int Ed Engl; 2022 May; 61(22):e202115805. PubMed ID: 35299278
[TBL] [Abstract][Full Text] [Related]
2. Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase.
Bolding JE; Martín-Gago P; Rajabi N; Gamon LF; Hansen TN; Bartling CRO; Strømgaard K; Davies MJ; Olsen CA
Angew Chem Int Ed Engl; 2022 Nov; 61(47):e202204565. PubMed ID: 36130196
[TBL] [Abstract][Full Text] [Related]
3. Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme.
Madsen AS; Olsen CA
J Med Chem; 2012 Jun; 55(11):5582-90. PubMed ID: 22583019
[TBL] [Abstract][Full Text] [Related]
4. Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5.
Fiorentino F; Castiello C; Mai A; Rotili D
J Med Chem; 2022 Jul; 65(14):9580-9606. PubMed ID: 35802779
[TBL] [Abstract][Full Text] [Related]
5. Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M; Peng C; Anderson KA; Chhoy P; Xie Z; Dai L; Park J; Chen Y; Huang H; Zhang Y; Ro J; Wagner GR; Green MF; Madsen AS; Schmiesing J; Peterson BS; Xu G; Ilkayeva OR; Muehlbauer MJ; Braulke T; Mühlhausen C; Backos DS; Olsen CA; McGuire PJ; Pletcher SD; Lombard DB; Hirschey MD; Zhao Y
Cell Metab; 2014 Apr; 19(4):605-17. PubMed ID: 24703693
[TBL] [Abstract][Full Text] [Related]
6. Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors.
Liu S; Ji S; Yu ZJ; Wang HL; Cheng X; Li WJ; Jing L; Yu Y; Chen Q; Yang LL; Li GB; Wu Y
Chem Biol Drug Des; 2018 Jan; 91(1):257-268. PubMed ID: 28756638
[TBL] [Abstract][Full Text] [Related]
7. New ε-N-thioglutaryl-lysine derivatives as SIRT5 inhibitors: Chemical synthesis, kinetic and crystallographic studies.
Deng J; Liu ZM; Zhu KR; Cui GL; Liu LX; Yan YH; Ning XL; Yu ZJ; Li GB; Qi QR
Bioorg Chem; 2023 Jun; 135():106487. PubMed ID: 36996510
[TBL] [Abstract][Full Text] [Related]
8. Cyclic Tripeptide-based Potent and Selective Human SIRT5 Inhibitors.
Jiang Y; Zheng W
Med Chem; 2020; 16(3):358-367. PubMed ID: 31161996
[TBL] [Abstract][Full Text] [Related]
9. Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology.
Kumar S; Lombard DB
Crit Rev Biochem Mol Biol; 2018 Jun; 53(3):311-334. PubMed ID: 29637793
[TBL] [Abstract][Full Text] [Related]
10. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight.
Rajabi N; Auth M; Troelsen KR; Pannek M; Bhatt DP; Fontenas M; Hirschey MD; Steegborn C; Madsen AS; Olsen CA
Angew Chem Int Ed Engl; 2017 Nov; 56(47):14836-14841. PubMed ID: 29044784
[TBL] [Abstract][Full Text] [Related]
11. Discovery of new human Sirtuin 5 inhibitors by mimicking glutaryl-lysine substrates.
Yang F; Su H; Deng J; Mou L; Wang H; Li R; Dai QQ; Yan YH; Qian S; Wang Z; Li GB; Yang L
Eur J Med Chem; 2021 Dec; 225():113803. PubMed ID: 34461505
[TBL] [Abstract][Full Text] [Related]
12. Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Yang LL; Wang HL; Yan YH; Liu S; Yu ZJ; Huang MY; Luo Y; Zheng X; Yu Y; Li GB
Eur J Med Chem; 2020 Apr; 192():112201. PubMed ID: 32163813
[TBL] [Abstract][Full Text] [Related]
13. Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors.
Yao J; Yin Y; Han H; Chen S; Zheng Y; Liang B; Wu M; Shu K; Debnath B; Lombard DB; Wang Q; Cheng K; Neamati N; Liu Y
Eur J Med Chem; 2023 Feb; 247():115024. PubMed ID: 36543033
[TBL] [Abstract][Full Text] [Related]
14. Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants.
Kalous KS; Wynia-Smith SL; Summers SB; Smith BC
J Biol Chem; 2020 Jun; 295(25):8524-8536. PubMed ID: 32371394
[TBL] [Abstract][Full Text] [Related]
15. Generation and Purification of Catalytically Active Recombinant Sirtuin5 (SIRT5) Protein.
Kumar S; Lombard DB
Methods Mol Biol; 2016; 1436():241-57. PubMed ID: 27246219
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of the human deacylase Sirtuin 5 by the indole GW5074.
Suenkel B; Fischer F; Steegborn C
Bioorg Med Chem Lett; 2013 Jan; 23(1):143-6. PubMed ID: 23195732
[TBL] [Abstract][Full Text] [Related]
17. Thiosuccinyl peptides as Sirt5-specific inhibitors.
He B; Du J; Lin H
J Am Chem Soc; 2012 Feb; 134(4):1922-5. PubMed ID: 22263694
[TBL] [Abstract][Full Text] [Related]
18. Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection.
Fabbrizi E; Fiorentino F; Carafa V; Altucci L; Mai A; Rotili D
Cells; 2023 Mar; 12(6):. PubMed ID: 36980194
[TBL] [Abstract][Full Text] [Related]
19. Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.
Sadhukhan S; Liu X; Ryu D; Nelson OD; Stupinski JA; Li Z; Chen W; Zhang S; Weiss RS; Locasale JW; Auwerx J; Lin H
Proc Natl Acad Sci U S A; 2016 Apr; 113(16):4320-5. PubMed ID: 27051063
[TBL] [Abstract][Full Text] [Related]
20. Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.
Bhatt DP; Mills CA; Anderson KA; Henriques BJ; Lucas TG; Francisco S; Liu J; Ilkayeva OR; Adams AE; Kulkarni SR; Backos DS; Major MB; Grimsrud PA; Gomes CM; Hirschey MD
J Biol Chem; 2022 Apr; 298(4):101723. PubMed ID: 35157847
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
