Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 35305671)

  • 1. Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin-proteasome pathway.
    Gong RH; Chen M; Huang C; Wong HLX; Kwan HY; Bian Z
    Cell Commun Signal; 2022 Mar; 20(1):34. PubMed ID: 35305671
    [TBL] [Abstract][Full Text] [Related]  

  • 2. beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.
    Li X; Liu J; Gao T
    Mol Cell Biol; 2009 Dec; 29(23):6192-205. PubMed ID: 19797085
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LPS impairs phospholipid synthesis by triggering beta-transducin repeat-containing protein (beta-TrCP)-mediated polyubiquitination and degradation of the surfactant enzyme acyl-CoA:lysophosphatidylcholine acyltransferase I (LPCAT1).
    Zou C; Butler PL; Coon TA; Smith RM; Hammen G; Zhao Y; Chen BB; Mallampalli RK
    J Biol Chem; 2011 Jan; 286(4):2719-27. PubMed ID: 21068446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation.
    Shanzer M; Adler J; Ricardo-Lax I; Reuven N; Shaul Y
    Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1678-1683. PubMed ID: 28154141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization.
    Ding Q; He X; Hsu JM; Xia W; Chen CT; Li LY; Lee DF; Liu JC; Zhong Q; Wang X; Hung MC
    Mol Cell Biol; 2007 Jun; 27(11):4006-17. PubMed ID: 17387146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCF
    Ci Y; Li X; Chen M; Zhong J; North BJ; Inuzuka H; He X; Li Y; Guo J; Dai X
    Protein Cell; 2018 Oct; 9(10):879-889. PubMed ID: 29497989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells.
    Wei S; Yang HC; Chuang HC; Yang J; Kulp SK; Lu PJ; Lai MD; Chen CS
    J Biol Chem; 2008 Sep; 283(39):26759-70. PubMed ID: 18650423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UV-induced degradation of securin is mediated by SKP1-CUL1-beta TrCP E3 ubiquitin ligase.
    Limón-Mortés MC; Mora-Santos M; Espina A; Pintor-Toro JA; López-Román A; Tortolero M; Romero F
    J Cell Sci; 2008 Jun; 121(11):1825-31. PubMed ID: 18460583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Long noncoding RNA SNHG14 accelerates cell proliferation, migration, invasion and suppresses apoptosis in colorectal cancer cells by targeting miR-944/KRAS axis through PI3K/AKT pathway.
    Pei Q; Liu GS; Li HP; Zhang Y; Xu XC; Gao H; Zhang W; Li T
    Eur Rev Med Pharmacol Sci; 2019 Nov; 23(22):9871-9881. PubMed ID: 31799655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KCTD1 suppresses canonical Wnt signaling pathway by enhancing β-catenin degradation.
    Li X; Chen C; Wang F; Huang W; Liang Z; Xiao Y; Wei K; Wan Z; Hu X; Xiang S; Ding X; Zhang J
    PLoS One; 2014; 9(4):e94343. PubMed ID: 24736394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis.
    Ren H; Koo J; Guan B; Yue P; Deng X; Chen M; Khuri FR; Sun SY
    Mol Cancer; 2013 Nov; 12():146. PubMed ID: 24261825
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
    Rada P; Rojo AI; Chowdhry S; McMahon M; Hayes JD; Cuadrado A
    Mol Cell Biol; 2011 Mar; 31(6):1121-33. PubMed ID: 21245377
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression.
    He F; Chen H; Yang P; Wu Q; Zhang T; Wang C; Wei J; Chen Z; Hu H; Li W; Cao J
    Oncotarget; 2016 Dec; 7(49):81156-81171. PubMed ID: 27835604
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING Ligases.
    Davis KA; Morelli M; Patton JT
    mBio; 2017 Aug; 8(4):. PubMed ID: 28851847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
    Tu W; Liu J; Qian F; Zhu L; Li M; Zheng H; Zhu C
    J Med Virol; 2023 Mar; 95(3):e28620. PubMed ID: 36846904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the molecular mechanism of δ-catenin ubiquitination: Implication of β-TrCP-1 as a potential E3 ligase.
    Shrestha H; Yuan T; He Y; Moon PG; Shrestha N; Ryu T; Park SY; Cho YC; Lee CH; Baek MC; Cho S; Simkhada S; Kim H; Kim K
    Biochim Biophys Acta; 2016 Sep; 1863(9):2311-21. PubMed ID: 27316454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.
    Morelli M; Dennis AF; Patton JT
    mBio; 2015 Jan; 6(1):. PubMed ID: 25626907
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Andrographolide sensitizes KRAS-mutant colorectal cancer cells to cetuximab by inhibiting the EGFR/AKT and PDGFRβ/AKT signaling pathways.
    Liu YF; Feng ZQ; Chu TH; Yi B; Liu J; Yu H; Xue J; Wang YJ; Zhang CZ
    Phytomedicine; 2024 Apr; 126():155462. PubMed ID: 38394734
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SIRT1 suppresses cellular accumulation of β-TrCP E3 ligase via protein degradation.
    Woo SR; Byun JG; Kim YH; Park ER; Joo HY; Yun M; Shin HJ; Kim SH; Shen YN; Park JE; Park GH; Lee KH
    Biochem Biophys Res Commun; 2013 Nov; 441(4):831-7. PubMed ID: 24211209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.
    Wu K; Fuchs SY; Chen A; Tan P; Gomez C; Ronai Z; Pan ZQ
    Mol Cell Biol; 2000 Feb; 20(4):1382-93. PubMed ID: 10648623
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.