BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 35305999)

  • 1. 9-Nitro-20(S)-carbonate-camptothecin (NCP4), a novel prodrug of 9-nitrocamptothecin (9-NC), exhibits potent chemotherapeutic efficacy and improved safety against hepatocarcinoma.
    Zhou H; Zhang Y; Tian Y; Sun Y; Chen Y; Zhang Y; Zhu Q; Pan J; Qing C
    Eur J Pharmacol; 2022 May; 923():174898. PubMed ID: 35305999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor efficacy, toxicity and pharmacokinetics of 9-nitrocamptothecin: role of lactone ratio.
    Chen J; Hu RR; Yang XX; Gu W; Tian R; Gong F; Luo L; Fang F; Chen ZP; Cai BC
    Cancer Chemother Pharmacol; 2013 Oct; 72(4):925-9. PubMed ID: 23934323
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.
    Endo M; Miwa M; Ura M; Tanimura H; Taniguchi K; Miyazaki Y; Ohwada J; Tsukazaki M; Niizuma S; Murata T; Ozawa S; Suda H; Ogawa K; Nanba E; Nagao S; Shimma N; Yamada-Okabe H
    Cancer Chemother Pharmacol; 2010 Jan; 65(2):363-71. PubMed ID: 19495753
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.
    Zheng S; Chang S; Lu J; Chen Z; Xie L; Nie Y; He B; Zou S; Gu Z
    PLoS One; 2011; 6(6):e21064. PubMed ID: 21695227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 9-nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats.
    Dadashzadeh S; Derakhshandeh K; Shirazi FH
    Anticancer Drugs; 2008 Sep; 19(8):805-11. PubMed ID: 18690092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy.
    Lu L; Li B; Lin C; Li K; Liu G; Xia Z; Luo Z; Cai K
    J Mater Chem B; 2020 May; 8(17):3918-3928. PubMed ID: 32227058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antitumor effect of DX-8951, a novel camptothecin analog, on human pancreatic tumor cells and their CPT-11-resistant variants cultured in vitro and xenografted into nude mice.
    Takiguchi S; Kumazawa E; Shimazoe T; Tohgo A; Kono A
    Jpn J Cancer Res; 1997 Aug; 88(8):760-9. PubMed ID: 9330608
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice.
    Lu JL; Wang JC; Zhao SX; Liu XY; Zhao H; Zhang X; Zhou SF; Zhang Q
    Eur J Pharm Biopharm; 2008 Aug; 69(3):899-907. PubMed ID: 18434109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lactone stability and tissue distribution of free and liposomal encapsulated 9-nitrocamptothecin in rats following intravenous injection.
    Chen J; Cai B; Ping Q; Liu M; Guo J
    Drug Dev Ind Pharm; 2008 Aug; 34(8):853-9. PubMed ID: 18686092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of 9-nitrocamptothecin-in-cyclodextrin-in-liposomes modified with transferrin for the treating of tumor.
    Chen J; Lu S; Gu W; Peng P; Dong J; Xu F; Yang X; Xiong Z; Yang X
    Int J Pharm; 2015 Jul; 490(1-2):219-28. PubMed ID: 26004006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of novel 7-ethyl-10-fluoro-20-O-(cinnamic acid ester)-camptothecin derivatives as potential high selectivity and low toxicity topoisomerase I inhibitors for hepatocellular carcinoma.
    Bai YP; Yang CJ; Deng N; Zhang M; Zhang ZJ; Li L; Zhou Y; Luo XF; Xu CR; Zhang BQ; Ma Y; Liu YQ
    Biochem Pharmacol; 2022 Jun; 200():115049. PubMed ID: 35469784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics of lactone, carboxylate and total 9-nitrocamptothecin with different doses and administration routes in rats.
    Chen J; Ping Q; Guo J; Chu X; Song M
    Biopharm Drug Dispos; 2006 Mar; 27(2):53-9. PubMed ID: 16299828
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative disposition of the antineoplastic agent 9-nitrocampotothecin and the inactive isomer 12-nitro camptothecin in CASE-bearing nude mice: effect of route of administration on tissue distribution.
    Ahmed AE; Jacob S; Giovanella BC; Kozielski AJ; Liehr JG; Stehlin JS
    Cancer Chemother Pharmacol; 1997; 41(1):29-36. PubMed ID: 9443611
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor potential of a novel camptothecin derivative, ZBH-ZM-06.
    Wu D; Zhao DW; Li YQ; Shi WG; Yin QL; Tu ZK; Yu YY; Zhong BH; Yu H; Bao WG
    Oncol Rep; 2018 Feb; 39(2):871-879. PubMed ID: 29251321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
    Zhang M; Zhu LZ; Yang CJ; Yan JX; Wang ZP; Bai YP; Peng LZ; Luo HB; Zhang ZJ; Li L; Xu CR; Liu YQ
    Bioorg Chem; 2023 Oct; 139():106652. PubMed ID: 37390632
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anticancer activity of new haloalkyl camptothecin esters against human cancer cell lines and human tumor xenografts grown in nude mice.
    Cao Z; Mendoza J; Kozielski A; Liu X; Dejesus A; Wang Y; Zhan CG; Vardeman D; Giovanella B
    Anticancer Agents Med Chem; 2012 Sep; 12(7):818-28. PubMed ID: 22583427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of injection routes on pharmacokinetics and lactone/carboxylate equilibrium of 9-Nitrocamptothecin in rats.
    Chen J; Ping Q; Guo J; Liu M; Cai B
    Int J Pharm; 2007 Aug; 340(1-2):29-33. PubMed ID: 17446016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Antitumor Properties of BQC-Glucuronide, a Camptothecin Prodrug for Selective Tumor Activation.
    Prijovich ZM; Burnouf PA; Chou HC; Huang PT; Chen KC; Cheng TL; Leu YL; Roffler SR
    Mol Pharm; 2016 Apr; 13(4):1242-50. PubMed ID: 26824303
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationship of alkyl camptothecin esters.
    Cao Z; Pantazis P; Mendoza J; Early J; Kozielski A; Harris N; Vardeman D; Liehr J; Stehlin JS; Giovanella B
    Ann N Y Acad Sci; 2000; 922():122-35. PubMed ID: 11193888
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin.
    Lu J; Liu C; Wang P; Ghazwani M; Xu J; Huang Y; Ma X; Zhang P; Li S
    Biomaterials; 2015 Sep; 62():176-87. PubMed ID: 26057133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.