These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 35310840)

  • 1. Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase.
    Wang C; Krüger A; Du X; Wrenger C; Groves MR
    Front Cell Infect Microbiol; 2022; 12():841833. PubMed ID: 35310840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
    Lunev S; Bosch SS; Batista Fde A; Wrenger C; Groves MR
    Acta Crystallogr F Struct Biol Commun; 2016 Jul; 72(Pt 7):523-33. PubMed ID: 27380369
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
    Lunev S; Bosch SS; Batista FA; Wang C; Li J; Linzke M; Kruithof P; Chamoun G; Dömling ASS; Wrenger C; Groves MR
    Biochem Biophys Res Commun; 2018 Mar; 497(3):835-842. PubMed ID: 29476738
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Target Validation of Aspartate Transcarbamoylase from
    Bosch SS; Lunev S; Batista FA; Linzke M; Kronenberger T; Dömling ASS; Groves MR; Wrenger C
    ACS Infect Dis; 2020 May; 6(5):986-999. PubMed ID: 32129597
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development.
    Lei Z; Wang B; Lu Z; Wang N; Tan H; Zheng J; Jia Z
    FEBS J; 2020 Aug; 287(16):3579-3599. PubMed ID: 31967710
    [TBL] [Abstract][Full Text] [Related]  

  • 6. T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition.
    Heng S; Stieglitz KA; Eldo J; Xia J; Cardia JP; Kantrowitz ER
    Biochemistry; 2006 Aug; 45(33):10062-71. PubMed ID: 16906764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells.
    Wang C; Zhang B; Cong Y; Du X; Chen S; Visser L; Ruiz-Moreno AJ; Zhang L; Reggiori F; Dömling ASS; Groves MR
    ChemMedChem; 2024 Jul; 19(13):e202300688. PubMed ID: 38602859
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors of Aspartate Transcarbamoylase Inhibit Mycobacterium tuberculosis Growth.
    Du X; Sonawane V; Zhang B; Wang C; de Ruijter B; Dömling ASS; Reiling N; Groves MR
    ChemMedChem; 2023 Sep; 18(17):e202300279. PubMed ID: 37294060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure and mechanisms of Escherichia coli aspartate transcarbamoylase.
    Lipscomb WN; Kantrowitz ER
    Acc Chem Res; 2012 Mar; 45(3):444-53. PubMed ID: 22011033
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain.
    Serre V; Guy H; Penverne B; Lux M; Rotgeri A; Evans D; Hervé G
    J Biol Chem; 1999 Aug; 274(34):23794-801. PubMed ID: 10446140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystallographic snapshots of the complete catalytic cycle of the unregulated aspartate transcarbamoylase from Bacillus subtilis.
    Harris KM; Cockrell GM; Puleo DE; Kantrowitz ER
    J Mol Biol; 2011 Aug; 411(1):190-200. PubMed ID: 21663747
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystallization and preliminary X-ray analysis of aspartate transcarbamoylase from the parasitic protist Trypanosoma cruzi.
    Matoba K; Nara T; Aoki T; Honma T; Tanaka A; Inoue M; Matsuoka S; Inaoka DK; Kita K; Harada S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Sep; 65(Pt 9):933-6. PubMed ID: 19724137
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystallization and structure determination of the catalytic trimer of Methanococcus jannaschii aspartate transcarbamoylase.
    Vitali J; Vorobyova T; Webster G; Kantrowitz ER
    Acta Crystallogr D Biol Crystallogr; 2000 Aug; 56(Pt 8):1061-3. PubMed ID: 10944354
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A reciprocal allosteric mechanism for efficient transfer of labile intermediates between active sites in CAD, the mammalian pyrimidine-biosynthetic multienzyme polypeptide.
    Irvine HS; Shaw SM; Paton A; Carrey EA
    Eur J Biochem; 1997 Aug; 247(3):1063-73. PubMed ID: 9288932
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
    Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
    Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-phosphonacetyl-L-isoasparagine a potent and specific inhibitor of Escherichia coli aspartate transcarbamoylase.
    Eldo J; Cardia JP; O'Day EM; Xia J; Tsuruta H; Kantrowitz ER
    J Med Chem; 2006 Oct; 49(20):5932-8. PubMed ID: 17004708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of Small-Molecule Allosteric Inhibitors of
    Wang C; Zhang B; Krüger A; Du X; Visser L; Dömling ASS; Wrenger C; Groves MR
    J Am Chem Soc; 2022 Oct; 144(41):19070-19077. PubMed ID: 36195578
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-tumoral Drug PALA.
    Ruiz-Ramos A; Velázquez-Campoy A; Grande-García A; Moreno-Morcillo M; Ramón-Maiques S
    Structure; 2016 Jul; 24(7):1081-94. PubMed ID: 27265852
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression, purification, crystallization and preliminary X-ray crystallographic studies of a cold-adapted aspartate carbamoyltransferase from Moritella profunda.
    De Vos D; Hulpiau P; Vergauwen B; Savvides SN; Van Beeumen J
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Mar; 61(Pt 3):279-81. PubMed ID: 16511017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pathway of product release from the R state of aspartate transcarbamoylase.
    Mendes KR; Kantrowitz ER
    J Mol Biol; 2010 Sep; 401(5):940-8. PubMed ID: 20620149
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.