These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
172 related articles for article (PubMed ID: 35317680)
1. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. Fioravanti R; Rodriguez V; Caroli J; Chianese U; Benedetti R; Di Bello E; Noce B; Zwergel C; Corinti D; Viña D; Altucci L; Mattevi A; Valente S; Mai A J Enzyme Inhib Med Chem; 2022 Dec; 37(1):973-985. PubMed ID: 35317680 [TBL] [Abstract][Full Text] [Related]
2. Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors. Ji YY; Lin SD; Wang YJ; Su MB; Zhang W; Gunosewoyo H; Yang F; Li J; Tang J; Zhou YB; Yu LF Eur J Med Chem; 2017 Dec; 141():101-112. PubMed ID: 29031059 [TBL] [Abstract][Full Text] [Related]
3. Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation. Fioravanti R; Romanelli A; Mautone N; Di Bello E; Rovere A; Corinti D; Zwergel C; Valente S; Rotili D; Botrugno OA; Dessanti P; Vultaggio S; Vianello P; Cappa A; Binda C; Mattevi A; Minucci S; Mercurio C; Varasi M; Mai A ChemMedChem; 2020 Apr; 15(7):643-658. PubMed ID: 32003940 [TBL] [Abstract][Full Text] [Related]
4. New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation. Liang L; Wang H; Du Y; Luo B; Meng N; Cen M; Huang P; Ganesan A; Wen S Bioorg Chem; 2020 Jun; 99():103808. PubMed ID: 32334189 [TBL] [Abstract][Full Text] [Related]
5. Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts. Valente S; Rodriguez V; Mercurio C; Vianello P; Saponara B; Cirilli R; Ciossani G; Labella D; Marrocco B; Monaldi D; Ruoppolo G; Tilset M; Botrugno OA; Dessanti P; Minucci S; Mattevi A; Varasi M; Mai A Eur J Med Chem; 2015 Apr; 94():163-74. PubMed ID: 25768700 [TBL] [Abstract][Full Text] [Related]
6. Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors. Benelkebir H; Hodgkinson C; Duriez PJ; Hayden AL; Bulleid RA; Crabb SJ; Packham G; Ganesan A Bioorg Med Chem; 2011 Jun; 19(12):3709-16. PubMed ID: 21382717 [TBL] [Abstract][Full Text] [Related]
7. Discovery of new tranylcypromine derivatives as highly potent LSD1 inhibitors. Huang MJ; Guo JW; Fu YD; You YZ; Xu WY; Song TY; Li R; Chen ZT; Huang LH; Liu HM Bioorg Med Chem Lett; 2021 Jun; 41():127993. PubMed ID: 33775841 [TBL] [Abstract][Full Text] [Related]
8. Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia. Teresa Borrello M; Benelkebir H; Lee A; Hin Tam C; Shafat M; Rushworth SA; Bowles KM; Douglas L; Duriez PJ; Bailey S; Crabb SJ; Packham G; Ganesan A ChemMedChem; 2021 Apr; 16(8):1316-1324. PubMed ID: 33533576 [TBL] [Abstract][Full Text] [Related]
9. Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation. Schulz-Fincke J; Hau M; Barth J; Robaa D; Willmann D; Kürner A; Haas J; Greve G; Haydn T; Fulda S; Lübbert M; Lüdeke S; Berg T; Sippl W; Schüle R; Jung M Eur J Med Chem; 2018 Jan; 144():52-67. PubMed ID: 29247860 [TBL] [Abstract][Full Text] [Related]
10. Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity. Ourailidou ME; Lenoci A; Zwergel C; Rotili D; Mai A; Dekker FJ Bioorg Med Chem; 2017 Feb; 25(3):847-856. PubMed ID: 27989416 [TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment. Duan YC; Ma YC; Qin WP; Ding LN; Zheng YC; Zhu YL; Zhai XY; Yang J; Ma CY; Guan YY Eur J Med Chem; 2017 Nov; 140():392-402. PubMed ID: 28987602 [TBL] [Abstract][Full Text] [Related]
13. Novel Tranylcypromine/Hydroxylcinnamic Acid Hybrids as Lysine-Specific Demethylase 1 Inhibitors with Potent Antitumor Activity. Han Y; Wu C; Lv H; Liu N; Deng H Chem Pharm Bull (Tokyo); 2015; 63(11):882-9. PubMed ID: 26521853 [TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer. Duan YC; Jin LF; Ren HM; Zhang SJ; Liu YJ; Xu YT; He ZH; Song Y; Yuan H; Chen SH; Guan YY Eur J Med Chem; 2021 Aug; 220():113453. PubMed ID: 33957387 [TBL] [Abstract][Full Text] [Related]
15. Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment. Zheng YC; Yu B; Jiang GZ; Feng XJ; He PX; Chu XY; Zhao W; Liu HM Curr Top Med Chem; 2016; 16(19):2179-88. PubMed ID: 26881714 [TBL] [Abstract][Full Text] [Related]
16. Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective. Dai XJ; Liu Y; Xiong XP; Xue LP; Zheng YC; Liu HM J Med Chem; 2020 Dec; 63(23):14197-14215. PubMed ID: 32931269 [TBL] [Abstract][Full Text] [Related]
17. [1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors. Li ZH; Ma JL; Liu GZ; Zhang XH; Qin TT; Ren WH; Zhao TQ; Chen XH; Zhang ZQ Eur J Med Chem; 2020 Feb; 187():111989. PubMed ID: 31881456 [TBL] [Abstract][Full Text] [Related]
18. Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor. Wang X; Su M; Li Y; Liu T; Wang Y; Chen Y; Tang L; He YP; Ding X; Yu F; Shen J; Li J; Zhou Y; Chen YL; Xiong B Bioorg Med Chem Lett; 2019 Mar; 29(6):844-847. PubMed ID: 30713023 [TBL] [Abstract][Full Text] [Related]
19. Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. Binda C; Valente S; Romanenghi M; Pilotto S; Cirilli R; Karytinos A; Ciossani G; Botrugno OA; Forneris F; Tardugno M; Edmondson DE; Minucci S; Mattevi A; Mai A J Am Chem Soc; 2010 May; 132(19):6827-33. PubMed ID: 20415477 [TBL] [Abstract][Full Text] [Related]