These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 35326469)

  • 1. A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.
    Marchand A; Sarchione A; Athanasopoulos PS; Roy HB; Goveas L; Magnez R; Drouyer M; Emanuele M; Ho FY; Liberelle M; Melnyk P; Lebègue N; Thuru X; Nichols RJ; Greggio E; Kortholt A; Galli T; Chartier-Harlin MC; Taymans JM
    Cells; 2022 Mar; 11(6):. PubMed ID: 35326469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.
    Unapanta A; Shavarebi F; Porath J; Shen Y; Balen C; Nguyen A; Tseng J; Leong WS; Liu M; Lis P; Di Pietro SM; Hiniker A
    J Biol Chem; 2023 Oct; 299(10):105192. PubMed ID: 37625589
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRRK2 Phosphorylation.
    Nichols RJ
    Adv Neurobiol; 2017; 14():51-70. PubMed ID: 28353278
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRRK2 Phosphorylation: Behind the Scenes.
    De Wit T; Baekelandt V; Lobbestael E
    Neuroscientist; 2018 Oct; 24(5):486-500. PubMed ID: 29385885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation.
    Drouyer M; Bolliger MF; Lobbestael E; Van den Haute C; Emanuele M; Lefebvre R; Sibran W; De Wit T; Leghay C; Mutez E; Dzamko N; Halliday GM; Murayama S; Martoriati A; Cailliau K; Bodart JF; Chartier-Harlin MC; Baekelandt V; Nichols RJ; Taymans JM
    Neurobiol Dis; 2021 Sep; 157():105426. PubMed ID: 34144124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes.
    Wang X; Bondar VV; Davis OB; Maloney MT; Agam M; Chin MY; Cheuk-Nga Ho A; Ghosh R; Leto DE; Joy D; Calvert MEK; Lewcock JW; Di Paolo G; Thorne RG; Sweeney ZK; Henry AG
    Elife; 2023 Oct; 12():. PubMed ID: 37874617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
    Purlyte E; Dhekne HS; Sarhan AR; Gomez R; Lis P; Wightman M; Martinez TN; Tonelli F; Pfeffer SR; Alessi DR
    EMBO J; 2018 Jan; 37(1):1-18. PubMed ID: 29212815
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner.
    Kania E; Long JS; McEwan DG; Welkenhuyzen K; La Rovere R; Luyten T; Halpin J; Lobbestael E; Baekelandt V; Bultynck G; Ryan KM; Parys JB
    Cell Death Dis; 2023 Jul; 14(7):436. PubMed ID: 37454104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of Rab29 at Ser185 regulates its localization and role in the lysosomal stress response in concert with LRRK2.
    Komori T; Kuwahara T; Fujimoto T; Sakurai M; Koyama-Honda I; Fukuda M; Iwatsubo T
    J Cell Sci; 2023 Jul; 136(14):. PubMed ID: 37365944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of phospho-specific Rab protein antibodies to monitor
    Lis P; Burel S; Steger M; Mann M; Brown F; Diez F; Tonelli F; Holton JL; Ho PW; Ho SL; Chou MY; Polinski NK; Martinez TN; Davies P; Alessi DR
    Biochem J; 2018 Jan; 475(1):1-22. PubMed ID: 29127256
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.
    Rivero-Ríos P; Romo-Lozano M; Madero-Pérez J; Thomas AP; Biosa A; Greggio E; Hilfiker S
    J Biol Chem; 2019 Mar; 294(13):4738-4758. PubMed ID: 30709905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
    Mir R; Tonelli F; Lis P; Macartney T; Polinski NK; Martinez TN; Chou MY; Howden AJM; König T; Hotzy C; Milenkovic I; Brücke T; Zimprich A; Sammler E; Alessi DR
    Biochem J; 2018 Jun; 475(11):1861-1883. PubMed ID: 29743203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Parkinson's disease-associated mutant LRRK2 phosphorylates Rab7L1 and modifies trans-Golgi morphology.
    Fujimoto T; Kuwahara T; Eguchi T; Sakurai M; Komori T; Iwatsubo T
    Biochem Biophys Res Commun; 2018 Jan; 495(2):1708-1715. PubMed ID: 29223392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation.
    Madero-Pérez J; Fdez E; Fernández B; Lara Ordóñez AJ; Blanca Ramírez M; Gómez-Suaga P; Waschbüsch D; Lobbestael E; Baekelandt V; Nairn AC; Ruiz-Martínez J; Aiastui A; López de Munain A; Lis P; Comptdaer T; Taymans JM; Chartier-Harlin MC; Beilina A; Gonnelli A; Cookson MR; Greggio E; Hilfiker S
    Mol Neurodegener; 2018 Jan; 13(1):3. PubMed ID: 29357897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation.
    Kuwahara T; Funakawa K; Komori T; Sakurai M; Yoshii G; Eguchi T; Fukuda M; Iwatsubo T
    Neurobiol Dis; 2020 Nov; 145():105081. PubMed ID: 32919031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Cell Biology of LRRK2 in Parkinson's Disease.
    Usmani A; Shavarebi F; Hiniker A
    Mol Cell Biol; 2021 Apr; 41(5):. PubMed ID: 33526455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression.
    Henry AG; Aghamohammadzadeh S; Samaroo H; Chen Y; Mou K; Needle E; Hirst WD
    Hum Mol Genet; 2015 Nov; 24(21):6013-28. PubMed ID: 26251043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Two Methods to Analyze LRRK2 Functions Under Lysosomal Stress: The Measurements of Cathepsin Release and Lysosomal Enlargement.
    Sakurai M; Kuwahara T
    Methods Mol Biol; 2021; 2322():63-72. PubMed ID: 34043193
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lysosomal positioning regulates Rab10 phosphorylation at LRRK2
    Kluss JH; Beilina A; Williamson CD; Lewis PA; Cookson MR; Bonet-Ponce L
    Proc Natl Acad Sci U S A; 2022 Oct; 119(43):e2205492119. PubMed ID: 36256825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
    Snead DM; Matyszewski M; Dickey AM; Lin YX; Leschziner AE; Reck-Peterson SL
    Nat Struct Mol Biol; 2022 Dec; 29(12):1196-1207. PubMed ID: 36510024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.