197 related articles for article (PubMed ID: 35331738)
1. Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
He J; Zou LN; Pareek V; Benkovic SJ
J Biol Chem; 2022 May; 298(5):101853. PubMed ID: 35331738
[TBL] [Abstract][Full Text] [Related]
2. Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
Goswami MT; Chen G; Chakravarthi BV; Pathi SS; Anand SK; Carskadon SL; Giordano TJ; Chinnaiyan AM; Thomas DG; Palanisamy N; Beer DG; Varambally S
Oncotarget; 2015 Sep; 6(27):23445-61. PubMed ID: 26140362
[TBL] [Abstract][Full Text] [Related]
3. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.
Ng A; Uribe RA; Yieh L; Nuckels R; Gross JM
Development; 2009 Aug; 136(15):2601-11. PubMed ID: 19570845
[TBL] [Abstract][Full Text] [Related]
4. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
[TBL] [Abstract][Full Text] [Related]
5. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
Li SX; Tong YP; Xie XC; Wang QH; Zhou HN; Han Y; Zhang ZY; Gao W; Li SG; Zhang XC; Bi RC
J Mol Biol; 2007 Mar; 366(5):1603-14. PubMed ID: 17224163
[TBL] [Abstract][Full Text] [Related]
6. PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
Pelet A; Skopova V; Steuerwald U; Baresova V; Zarhrate M; Plaza JM; Hnizda A; Krijt M; Souckova O; Wibrand F; Andorsdóttir G; Joensen F; Sedlak D; Bleyer AJ; Kmoch S; Lyonnet S; Zikanova M
Hum Mol Genet; 2019 Nov; 28(22):3805-3814. PubMed ID: 31600779
[TBL] [Abstract][Full Text] [Related]
7. PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly.
Chou MC; Wang YH; Chen FY; Kung CY; Wu KP; Kuo JC; Chan SJ; Cheng ML; Lin CY; Chou YC; Ho MC; Firestine S; Huang JR; Chen RH
Mol Cell; 2023 Nov; 83(22):4123-4140.e12. PubMed ID: 37848033
[TBL] [Abstract][Full Text] [Related]
8. Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis.
Zhao H; Chiaro CR; Zhang L; Smith PB; Chan CY; Pedley AM; Pugh RJ; French JB; Patterson AD; Benkovic SJ
J Biol Chem; 2015 Mar; 290(11):6705-13. PubMed ID: 25605736
[TBL] [Abstract][Full Text] [Related]
9. Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
Chakravarthi BV; Goswami MT; Pathi SS; Dodson M; Chandrashekar DS; Agarwal S; Nepal S; Hodigere Balasubramanya SA; Siddiqui J; Lonigro RJ; Chinnaiyan AM; Kunju LP; Palanisamy N; Varambally S
Prostate; 2017 Jan; 77(1):10-21. PubMed ID: 27550065
[TBL] [Abstract][Full Text] [Related]
10. Human de novo purine biosynthesis.
Pareek V; Pedley AM; Benkovic SJ
Crit Rev Biochem Mol Biol; 2021 Feb; 56(1):1-16. PubMed ID: 33179964
[TBL] [Abstract][Full Text] [Related]
11. Dynamic architecture of the purinosome involved in human de novo purine biosynthesis.
Kyoung M; Russell SJ; Kohnhorst CL; Esemoto NN; An S
Biochemistry; 2015 Jan; 54(3):870-80. PubMed ID: 25540829
[TBL] [Abstract][Full Text] [Related]
12. Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of
Shon H; Matveeva EA; Jull EC; Hu Y; Coupet TA; Lee YS
Biochemistry; 2022 Apr; 61(7):575-582. PubMed ID: 35285625
[TBL] [Abstract][Full Text] [Related]
13. Purinosome formation as a function of the cell cycle.
Chan CY; Zhao H; Pugh RJ; Pedley AM; French J; Jones SA; Zhuang X; Jinnah H; Huang TJ; Benkovic SJ
Proc Natl Acad Sci U S A; 2015 Feb; 112(5):1368-73. PubMed ID: 25605889
[TBL] [Abstract][Full Text] [Related]
14. PAICS as a potential target for cancer therapy linking purine biosynthesis to cancer progression.
Huo A; Xiong X
Life Sci; 2023 Oct; 331():122070. PubMed ID: 37673296
[TBL] [Abstract][Full Text] [Related]
15. A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
Chakravarthi BVSK; Rodriguez Pena MDC; Agarwal S; Chandrashekar DS; Hodigere Balasubramanya SA; Jabboure FJ; Matoso A; Bivalacqua TJ; Rezaei K; Chaux A; Grizzle WE; Sonpavde G; Gordetsky J; Netto GJ; Varambally S
Neoplasia; 2018 Sep; 20(9):894-904. PubMed ID: 30121007
[TBL] [Abstract][Full Text] [Related]
16. The Purinosome: A Case Study for a Mammalian Metabolon.
Pedley AM; Pareek V; Benkovic SJ
Annu Rev Biochem; 2022 Jun; 91():89-106. PubMed ID: 35320684
[TBL] [Abstract][Full Text] [Related]
17. Mapping of the bovine genes of the de novo AMP synthesis pathway.
Bønsdorff T; Gautier M; Farstad W; Rønningen K; Lingaas F; Olsaker I
Anim Genet; 2004 Dec; 35(6):438-44. PubMed ID: 15566465
[TBL] [Abstract][Full Text] [Related]
18. Detecting Purinosome Metabolon Formation with Fluorescence Microscopy.
Pedley AM; Benkovic SJ
Methods Mol Biol; 2018; 1764():279-289. PubMed ID: 29605921
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
[TBL] [Abstract][Full Text] [Related]
20. Generation of a Rat Monoclonal Antibody for Human PAICS, a
Yokoyama C; Bando K; Yamagata M; Nagasaki T; Tachibana T
Monoclon Antib Immunodiagn Immunother; 2024 Jun; ():. PubMed ID: 38836825
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
