BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 35351864)

  • 1. Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice.
    Miranda AM; Ashok A; Chan RB; Zhou B; Xu Y; McIntire LB; Area-Gomez E; Di Paolo G; Duff KE; Oliveira TG; Nuriel T
    Transl Psychiatry; 2022 Mar; 12(1):129. PubMed ID: 35351864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apolipoprotein E ε4 modulates astrocyte neuronal support functions in the presence of amyloid-β.
    Fleeman RM; Kuhn MK; Chan DC; Proctor EA
    J Neurochem; 2023 May; 165(4):536-549. PubMed ID: 36762973
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice.
    Larramona-Arcas R; González-Arias C; Perea G; Gutiérrez A; Vitorica J; García-Barrera T; Gómez-Ariza JL; Pascua-Maestro R; Ganfornina MD; Kara E; Hudry E; Martinez-Vicente M; Vila M; Galea E; Masgrau R
    Mol Neurodegener; 2020 Jun; 15(1):35. PubMed ID: 32517777
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
    Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
    Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.
    Area-Gomez E; Larrea D; Pera M; Agrawal RR; Guilfoyle DN; Pirhaji L; Shannon K; Arain HA; Ashok A; Chen Q; Dillman AA; Figueroa HY; Cookson MR; Gross SS; Fraenkel E; Duff KE; Nuriel T
    Sci Rep; 2020 Mar; 10(1):4277. PubMed ID: 32152337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired Autophagy in APOE4 Astrocytes.
    Simonovitch S; Schmukler E; Bespalko A; Iram T; Frenkel D; Holtzman DM; Masliah E; Michaelson DM; Pinkas-Kramarski R
    J Alzheimers Dis; 2016; 51(3):915-27. PubMed ID: 26923027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
    Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
    J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Detection of early Alzheimer's disease-like molecular alterations in a mouse model expressing human ApoE4.
    Rai A; Ojiakor OA; Rylett RJ
    J Neurochem; 2023 Aug; 166(3):572-587. PubMed ID: 37415276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
    Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
    J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
    Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
    Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calcium-dependent cytosolic phospholipase A
    Wang S; Li B; Solomon V; Fonteh A; Rapoport SI; Bennett DA; Arvanitakis Z; Chui HC; Miller C; Sullivan PM; Wang HY; Yassine HN
    Mol Neurodegener; 2021 Apr; 16(1):26. PubMed ID: 33863362
    [TBL] [Abstract][Full Text] [Related]  

  • 12. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
    Deane R; Sagare A; Hamm K; Parisi M; Lane S; Finn MB; Holtzman DM; Zlokovic BV
    J Clin Invest; 2008 Dec; 118(12):4002-13. PubMed ID: 19033669
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits.
    Belinson H; Lev D; Masliah E; Michaelson DM
    J Neurosci; 2008 Apr; 28(18):4690-701. PubMed ID: 18448646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
    Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
    J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology.
    Nuriel T; Angulo SL; Khan U; Ashok A; Chen Q; Figueroa HY; Emrani S; Liu L; Herman M; Barrett G; Savage V; Buitrago L; Cepeda-Prado E; Fung C; Goldberg E; Gross SS; Hussaini SA; Moreno H; Small SA; Duff KE
    Nat Commun; 2017 Nov; 8(1):1464. PubMed ID: 29133888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
    Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
    Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Butterfield DA; Mattson MP
    Neurobiol Dis; 2020 May; 138():104795. PubMed ID: 32036033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice.
    Lattanzio F; Carboni L; Carretta D; Rimondini R; Candeletti S; Romualdi P
    Neuroscience; 2014 Jan; 256():360-9. PubMed ID: 24161275
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reversal of ApoE4-Driven Brain Pathology by Vascular Endothelial Growth Factor Treatment.
    Salomon-Zimri S; Glat MJ; Barhum Y; Luz I; Boehm-Cagan A; Liraz O; Ben-Zur T; Offen D; Michaelson DM
    J Alzheimers Dis; 2016 Jun; 53(4):1443-58. PubMed ID: 27372644
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.
    Prasad H; Rao R
    Proc Natl Acad Sci U S A; 2018 Jul; 115(28):E6640-E6649. PubMed ID: 29946028
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.