254 related articles for article (PubMed ID: 35352880)
1. AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.
Marino M; Zhou L; Rincon MY; Callaerts-Vegh Z; Verhaert J; Wahis J; Creemers E; Yshii L; Wierda K; Saito T; Marneffe C; Voytyuk I; Wouters Y; Dewilde M; Duqué SI; Vincke C; Levites Y; Golde TE; Saido TC; Muyldermans S; Liston A; De Strooper B; Holt MG
EMBO Mol Med; 2022 Apr; 14(4):e09824. PubMed ID: 35352880
[TBL] [Abstract][Full Text] [Related]
2. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
Dorresteijn B; Rotman M; Faber D; Schravesande R; Suidgeest E; van der Weerd L; van der Maarel SM; Verrips CT; El Khattabi M
FEBS J; 2015 Sep; 282(18):3618-31. PubMed ID: 26147692
[TBL] [Abstract][Full Text] [Related]
3. VHHs as tools for therapeutic protein delivery to the central nervous system.
Wouters Y; Jaspers T; Rué L; Serneels L; De Strooper B; Dewilde M
Fluids Barriers CNS; 2022 Oct; 19(1):79. PubMed ID: 36192747
[TBL] [Abstract][Full Text] [Related]
4. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
5. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
6. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ; Fernandez CG; Stanley M; Jiang H; Nguyen P; Rice RC; Buggia-Prévot V; De Rossi P; Vetrivel KS; Lamb R; Argemi A; Allaert ES; Rathbun EM; Krause SV; Wagner SL; Parent AT; Holtzman DM; Thinakaran G
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):E9665-E9674. PubMed ID: 29078331
[TBL] [Abstract][Full Text] [Related]
7. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
Kimura R; Devi L; Ohno M
J Neurochem; 2010 Apr; 113(1):248-61. PubMed ID: 20089133
[TBL] [Abstract][Full Text] [Related]
8. MiR-361-3p inhibits β-amyloid accumulation and attenuates cognitive deficits through targeting BACE1 in Alzheimer's disease.
Ji Y; Wang D; Zhang B; Lu H
J Integr Neurosci; 2019 Sep; 18(3):285-291. PubMed ID: 31601077
[TBL] [Abstract][Full Text] [Related]
9. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.
Sadleir KR; Eimer WA; Kaufman RJ; Osten P; Vassar R
PLoS One; 2014; 9(7):e101643. PubMed ID: 24992504
[TBL] [Abstract][Full Text] [Related]
10. Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease.
Wang P; Zheng X; Guo Q; Yang P; Pang X; Qian K; Lu W; Zhang Q; Jiang X
J Control Release; 2018 Jun; 279():220-233. PubMed ID: 29679667
[TBL] [Abstract][Full Text] [Related]
11. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
[TBL] [Abstract][Full Text] [Related]
12. Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases.
Cai Z; Wang C; He W; Chen Y
Curr Alzheimer Res; 2018; 15(11):1045-1052. PubMed ID: 29962345
[TBL] [Abstract][Full Text] [Related]
13. Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer's related amyloid-beta pathology.
Su S; Esparza TJ; Brody DL
PLoS One; 2022; 17(10):e0276107. PubMed ID: 36256604
[TBL] [Abstract][Full Text] [Related]
14. Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer's disease transgenic mice.
Arbel-Ornath M; Becker M; Rabinovich-Toidman P; Gartner M; Solomon B
J Alzheimers Dis; 2010; 22(2):469-82. PubMed ID: 20847413
[TBL] [Abstract][Full Text] [Related]
15. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
[TBL] [Abstract][Full Text] [Related]
16. Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level.
Sadleir KR; Eimer WA; Cole SL; Vassar R
Mol Neurodegener; 2015 Jan; 10():1. PubMed ID: 25567526
[TBL] [Abstract][Full Text] [Related]
17. A short peptide from sAPPα binding to BACE1-APP action site rescues Alzheimer-like pathology.
Lai X; Hu J; Liu H; Lan L; Long Y; Gao X; Deng J
Neurosci Lett; 2022 Jan; 770():136397. PubMed ID: 34915100
[TBL] [Abstract][Full Text] [Related]
18. Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Rotman M; Welling MM; van den Boogaard ML; Moursel LG; van der Graaf LM; van Buchem MA; van der Maarel SM; van der Weerd L
Nucl Med Biol; 2015 Aug; 42(8):695-702. PubMed ID: 25960433
[TBL] [Abstract][Full Text] [Related]
19. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
Sadleir KR; Kandalepas PC; Buggia-Prévot V; Nicholson DA; Thinakaran G; Vassar R
Acta Neuropathol; 2016 Aug; 132(2):235-256. PubMed ID: 26993139
[TBL] [Abstract][Full Text] [Related]
20. MiR-340 Reduces the Accumulation of Amyloid-β Through Targeting BACE1 (β-site Amyloid Precursor Protein Cleaving Enzyme 1) in Alzheimer's Disease.
Tan X; Luo Y; Pi D; Xia L; Li Z; Tu Q
Curr Neurovasc Res; 2020; 17(1):86-92. PubMed ID: 31957613
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
