These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 35355421)

  • 1. Design, Synthesis, and Biological Evaluation of Tetrahydro-α-carbolines as Akt1 Inhibitors That Inhibit Colorectal Cancer Cell Proliferation.
    Li G; He XH; Li HP; Zhao Q; Li DA; Zhu HP; Zhang YH; Zhan G; Huang W
    ChemMedChem; 2022 Jun; 17(11):e202200104. PubMed ID: 35355421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and Structure-Activity Relationships of Tetrahydro-β-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents.
    Zhang M; Park EJ; Kondratyuk TP; Pezzuto JM; Sun D
    Anticancer Res; 2018 Aug; 38(8):4425-4433. PubMed ID: 30061206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and evaluation of novel Akt1 inhibitors based on an indole scaffold.
    Yang D; Tong D; Zhang Q; Wang Y; Sun J; Zhang F; Zhao G
    Chem Biol Drug Des; 2017 Nov; 90(5):791-803. PubMed ID: 28390089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity.
    Tokala R; Sana S; Lakshmi UJ; Sankarana P; Sigalapalli DK; Gadewal N; Kode J; Shankaraiah N
    Bioorg Chem; 2020 Dec; 105():104357. PubMed ID: 33091673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
    Kovvuri J; Nagaraju B; Nayak VL; Akunuri R; Rao MPN; Ajitha A; Nagesh N; Kamal A
    Eur J Med Chem; 2018 Jan; 143():1563-1577. PubMed ID: 29129513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and molecular modeling of novel tetrahydro-β-carboline derivatives with phosphodiesterase 5 inhibitory and anticancer properties.
    Mohamed HA; Girgis NM; Wilcken R; Bauer MR; Tinsley HN; Gary BD; Piazza GA; Boeckler FM; Abadi AH
    J Med Chem; 2011 Jan; 54(2):495-509. PubMed ID: 21189023
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bivalent β-Carbolines Inhibit Colorectal Cancer Growth through Inducing Autophagy.
    Zhang H; Cao R; Zeng F; Fan W; Guo L; Ma Q; Ke S
    Chem Pharm Bull (Tokyo); 2021; 69(11):1104-1109. PubMed ID: 34719593
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-based design, synthesis and biological evaluation of diphenylmethylamine derivatives as novel Akt1 inhibitors.
    Liu T; Zhan W; Wang Y; Zhang L; Yang B; Dong X; Hu Y
    Eur J Med Chem; 2014 Feb; 73():167-76. PubMed ID: 24389511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, biological evaluation, and molecular docking of novel benzopyran and phenylpyrazole derivatives as Akt inhibitors.
    Zhan W; Lin S; Chen J; Dong X; Chu J; Du W
    Chem Biol Drug Des; 2015 Jun; 85(6):770-9. PubMed ID: 25453512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of novel 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole triazole derivatives as potent TRPV1 antagonists.
    Li J; Nie C; Qiao Y; Hu J; Li Q; Wang Q; Pu X; Yan L; Qian H
    Eur J Med Chem; 2019 Sep; 178():433-445. PubMed ID: 31202991
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
    Liu F; Yu LQ; Jiang C; Yang L; Wu WT; You QD
    Bioorg Med Chem; 2010 Jun; 18(12):4167-77. PubMed ID: 20537544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation.
    Xu G; Liu T; Zhou Y; Yang X; Fang H
    Bioorg Med Chem; 2017 Oct; 25(20):5548-5556. PubMed ID: 28866374
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In search of AKT kinase inhibitors as anticancer agents: structure-based design, docking, and molecular dynamics studies of 2,4,6-trisubstituted pyridines.
    Trejo-Soto PJ; Hernández-Campos A; Romo-Mancillas A; Medina-Franco JL; Castillo R
    J Biomol Struct Dyn; 2018 Feb; 36(2):423-442. PubMed ID: 28150530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.
    Zheng C; Fang Y; Tong W; Li G; Wu H; Zhou W; Lin Q; Yang F; Yang Z; Wang P; Peng Y; Pang X; Yi Z; Luo J; Liu M; Chen Y
    J Med Chem; 2014 Feb; 57(3):600-12. PubMed ID: 24417479
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of indolin-2-one derivatives as potent PAK4 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study.
    Guo J; Zhu M; Wu T; Hao C; Wang K; Yan Z; Huang W; Wang J; Zhao D; Cheng M
    Bioorg Med Chem; 2017 Jul; 25(13):3500-3511. PubMed ID: 28502459
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and Synthesis of DNA-Interactive β-Carboline-Oxindole Hybrids as Cytotoxic and Apoptosis-Inducing Agents.
    Tokala R; Thatikonda S; Vanteddu US; Sana S; Godugu C; Shankaraiah N
    ChemMedChem; 2018 Sep; 13(18):1909-1922. PubMed ID: 30010248
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure-activity relationship analysis.
    Zhong Y; Xue M; Zhao X; Yuan J; Liu X; Huang J; Zhao Z; Li H; Xu Y
    Bioorg Med Chem; 2013 Apr; 21(7):1724-34. PubMed ID: 23434140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and structure-activity relationship studies of novel 3,9-substituted α-carboline derivatives with high cytotoxic activity against colorectal cancer cells.
    Lin YC; Chen YF; Tseng LS; Lee YH; Morris-Natschke SL; Kuo SC; Yang NS; Lee KH; Huang LJ
    Eur J Med Chem; 2016 Mar; 110():98-114. PubMed ID: 26820553
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole-Indole Conjugates as Anticancer CDK Inhibitors.
    Al-Warhi T; El Kerdawy AM; Aljaeed N; Ismael OE; Ayyad RR; Eldehna WM; Abdel-Aziz HA; Al-Ansary GH
    Molecules; 2020 Apr; 25(9):. PubMed ID: 32349307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines.
    Jaromin A; Gryzło B; Jamrozik M; Parapini S; Basilico N; Cegła M; Taramelli D; Zagórska A
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948361
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.