161 related articles for article (PubMed ID: 35365657)
1. PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.
Schmid MC; Kang SW; Chen H; Paradise M; Ghebremedhin A; Kaneda MM; Chin SM; Do A; Watterson DM; Varner JA
Nat Commun; 2022 Apr; 13(1):1768. PubMed ID: 35365657
[TBL] [Abstract][Full Text] [Related]
2. PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
Schmid MC; Franco I; Kang SW; Hirsch E; Quilliam LA; Varner JA
PLoS One; 2013; 8(4):e60226. PubMed ID: 23565202
[TBL] [Abstract][Full Text] [Related]
3. PI3Kγ Activates Integrin α
Foubert P; Kaneda MM; Varner JA
Cancer Immunol Res; 2017 Nov; 5(11):957-968. PubMed ID: 28963139
[TBL] [Abstract][Full Text] [Related]
4. PI3Kγ is a molecular switch that controls immune suppression.
Kaneda MM; Messer KS; Ralainirina N; Li H; Leem CJ; Gorjestani S; Woo G; Nguyen AV; Figueiredo CC; Foubert P; Schmid MC; Pink M; Winkler DG; Rausch M; Palombella VJ; Kutok J; McGovern K; Frazer KA; Wu X; Karin M; Sasik R; Cohen EE; Varner JA
Nature; 2016 Nov; 539(7629):437-442. PubMed ID: 27642729
[TBL] [Abstract][Full Text] [Related]
5. Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Kaneda MM; Cappello P; Nguyen AV; Ralainirina N; Hardamon CR; Foubert P; Schmid MC; Sun P; Mose E; Bouvet M; Lowy AM; Valasek MA; Sasik R; Novelli F; Hirsch E; Varner JA
Cancer Discov; 2016 Aug; 6(8):870-85. PubMed ID: 27179037
[TBL] [Abstract][Full Text] [Related]
6. Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.
Schmid MC; Avraamides CJ; Dippold HC; Franco I; Foubert P; Ellies LG; Acevedo LM; Manglicmot JR; Song X; Wrasidlo W; Blair SL; Ginsberg MH; Cheresh DA; Hirsch E; Field SJ; Varner JA
Cancer Cell; 2011 Jun; 19(6):715-27. PubMed ID: 21665146
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation Regulates Interaction of 210-kDa Myosin Light Chain Kinase N-terminal Domain with Actin Cytoskeleton.
Vilitkevich EL; Khapchaev AY; Kudryashov DS; Nikashin AV; Schavocky JP; Lukas TJ; Watterson DM; Shirinsky VP
Biochemistry (Mosc); 2015 Oct; 80(10):1288-97. PubMed ID: 26567572
[TBL] [Abstract][Full Text] [Related]
8. Integrin alpha4beta1 promotes monocyte trafficking and angiogenesis in tumors.
Jin H; Su J; Garmy-Susini B; Kleeman J; Varner J
Cancer Res; 2006 Feb; 66(4):2146-52. PubMed ID: 16489015
[TBL] [Abstract][Full Text] [Related]
9. Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke.
Jin R; Song Z; Yu S; Piazza A; Nanda A; Penninger JM; Granger DN; Li G
Stroke; 2011 Jul; 42(7):2033-44. PubMed ID: 21546487
[TBL] [Abstract][Full Text] [Related]
10. Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions.
Wang C; Jin R; Nanda A; Yan J; Li G
PLoS One; 2015; 10(6):e0129265. PubMed ID: 26053836
[TBL] [Abstract][Full Text] [Related]
11. Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth.
Schmid MC; Avraamides CJ; Foubert P; Shaked Y; Kang SW; Kerbel RS; Varner JA
Cancer Res; 2011 Nov; 71(22):6965-75. PubMed ID: 21948958
[TBL] [Abstract][Full Text] [Related]
12. Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A.
Arora PD; Conti MA; Ravid S; Sacks DB; Kapus A; Adelstein RS; Bresnick AR; McCulloch CA
Mol Biol Cell; 2008 Dec; 19(12):5032-46. PubMed ID: 18799623
[TBL] [Abstract][Full Text] [Related]
13. Phosphoinositide-3 kinase gamma regulates caspase-1 activation and leukocyte recruitment in acute murine gout.
Tavares LD; Galvão I; Costa VV; Batista NV; Rossi LCR; Brito CB; Reis AC; Queiroz-Junior CM; Braga AD; Coelho FM; Dias AC; Zamboni DS; Pinho V; Teixeira MM; Amaral FA; Souza DG
J Leukoc Biol; 2019 Sep; 106(3):619-629. PubMed ID: 31392775
[TBL] [Abstract][Full Text] [Related]
14. Phosphatidylinositol-3-kinase-gamma is integral to homing functions of progenitor cells.
Chavakis E; Carmona G; Urbich C; Göttig S; Henschler R; Penninger JM; Zeiher AM; Chavakis T; Dimmeler S
Circ Res; 2008 Apr; 102(8):942-9. PubMed ID: 18323525
[TBL] [Abstract][Full Text] [Related]
15. The effect of pharmacological PI3Kγ inhibitor on eotaxin-induced human eosinophil functions.
Saito Y; Takeda M; Nishikawa J; Konno Y; Tamaki M; Itoga M; Kobayashi Y; Moritoki Y; Ito W; Chihara J; Ueki S
Pulm Pharmacol Ther; 2014 Apr; 27(2):164-9. PubMed ID: 24333185
[TBL] [Abstract][Full Text] [Related]
16. Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.
Shymanets A; Prajwal ; Vadas O; Czupalla C; LoPiccolo J; Brenowitz M; Ghigo A; Hirsch E; Krause E; Wetzker R; Williams RL; Harteneck C; Nürnberg B
Biochem J; 2015 Jul; 469(1):59-69. PubMed ID: 26173259
[TBL] [Abstract][Full Text] [Related]
17. Modified Jian-pi-yang-zheng decoction inhibits gastric cancer progression via the macrophage immune checkpoint PI3Kγ.
Yuan M; Zou X; Liu S; Xu X; Wang H; Zhu M; Xie X; Wang H; Wu J; Sun Q
Biomed Pharmacother; 2020 Sep; 129():110440. PubMed ID: 32768942
[TBL] [Abstract][Full Text] [Related]
18. Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition.
Carnevalli LS; Taylor MA; King M; Coenen-Stass AML; Hughes AM; Bell S; Proia TA; Wang Y; Ramos-Montoya A; Wali N; Carroll D; Singh M; Moschetta M; Gutierrez PM; Gardelli C; Critchlow SE; Klinowska T; Fawell SE; Barry ST
Mol Cancer Ther; 2021 Jun; 20(6):1080-1091. PubMed ID: 33785652
[TBL] [Abstract][Full Text] [Related]
19. Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia.
Braun DJ; Bachstetter AD; Sudduth TL; Wilcock DM; Watterson DM; Van Eldik LJ
Geroscience; 2019 Oct; 41(5):671-679. PubMed ID: 31104189
[TBL] [Abstract][Full Text] [Related]
20. Phosphoinositide 3 Kinase γ Plays a Critical Role in Acute Kidney Injury.
Jin X; Chu Q; Sun L; Tran M; Wang Y
Cells; 2022 Feb; 11(5):. PubMed ID: 35269396
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]