130 related articles for article (PubMed ID: 35385803)
1. Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.
Xiang Q; Luo G; Zhang C; Hu Q; Wang C; Wu T; Xu H; Hu J; Zhuang X; Zhang M; Wu S; Xu J; Zhang Y; Liu J; Xu Y
Eur J Med Chem; 2022 Jun; 236():114311. PubMed ID: 35385803
[TBL] [Abstract][Full Text] [Related]
2. Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Palmer WS; Poncet-Montange G; Liu G; Petrocchi A; Reyna N; Subramanian G; Theroff J; Yau A; Kost-Alimova M; Bardenhagen JP; Leo E; Shepard HE; Tieu TN; Shi X; Zhan Y; Zhao S; Barton MC; Draetta G; Toniatti C; Jones P; Geck Do M; Andersen JN
J Med Chem; 2016 Feb; 59(4):1440-54. PubMed ID: 26061247
[TBL] [Abstract][Full Text] [Related]
3. Development of small molecule inhibitors of BRPF1 and TRIM24 bromodomains.
Palmer WS
Drug Discov Today Technol; 2016 Mar; 19():65-71. PubMed ID: 27769360
[TBL] [Abstract][Full Text] [Related]
4. Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J; Fedorov O; Tallant C; Monteiro O; Meier J; Gamble V; Savitsky P; Nunez-Alonso GA; Haendler B; Rogers C; Brennan PE; Müller S; Knapp S
J Med Chem; 2016 Feb; 59(4):1642-7. PubMed ID: 25974391
[TBL] [Abstract][Full Text] [Related]
5. Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activities.
Hu Q; Wang C; Xiang Q; Wang R; Zhang C; Zhang M; Xue X; Luo G; Liu X; Wu X; Zhang Y; Wu D; Xu Y
Bioorg Chem; 2020 Jan; 94():103424. PubMed ID: 31776034
[TBL] [Abstract][Full Text] [Related]
6. Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Zhu J; Zhou C; Caflisch A
Eur J Med Chem; 2018 Jul; 155():337-352. PubMed ID: 29902720
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
Ghazy E; Zeyen P; Herp D; Hügle M; Schmidtkunz K; Erdmann F; Robaa D; Schmidt M; Morales ER; Romier C; Günther S; Jung M; Sippl W
Eur J Med Chem; 2020 Aug; 200():112338. PubMed ID: 32497960
[TBL] [Abstract][Full Text] [Related]
8. Integrated virtual screening and MD simulation approaches toward discovering potential inhibitors for targeting BRPF1 bromodomain in hepatocellular carcinoma.
Barman S; Bardhan I; Padhan J; Sudhamalla B
J Mol Graph Model; 2024 Jan; 126():108642. PubMed ID: 37797430
[TBL] [Abstract][Full Text] [Related]
9. Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.
Poplawski A; Hu K; Lee W; Natesan S; Peng D; Carlson S; Shi X; Balaz S; Markley JL; Glass KC
J Mol Biol; 2014 Apr; 426(8):1661-76. PubMed ID: 24333487
[TBL] [Abstract][Full Text] [Related]
10. Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer.
Cheng CL; Tsang FH; Wei L; Chen M; Chin DW; Shen J; Law CT; Lee D; Wong CC; Ng IO; Wong CM
Commun Biol; 2021 Jul; 4(1):888. PubMed ID: 34285329
[TBL] [Abstract][Full Text] [Related]
11. The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.
Liu J; Li F; Bao H; Jiang Y; Zhang S; Ma R; Gao J; Wu J; Ruan K
FEBS J; 2017 Apr; 284(7):1082-1095. PubMed ID: 28207202
[TBL] [Abstract][Full Text] [Related]
12. Uncovering the non-histone interactome of the BRPF1 bromodomain using site-specific azide-acetyllysine photochemistry.
Barman S; Padhan J; Sudhamalla B
J Biol Chem; 2024 Jan; 300(1):105551. PubMed ID: 38072045
[TBL] [Abstract][Full Text] [Related]
13. Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Lubula MY; Eckenroth BE; Carlson S; Poplawski A; Chruszcz M; Glass KC
FEBS Lett; 2014 Nov; 588(21):3844-54. PubMed ID: 25281266
[TBL] [Abstract][Full Text] [Related]
14. Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.
Lubula MY; Poplawaski A; Glass KC
Acta Crystallogr F Struct Biol Commun; 2014 Oct; 70(Pt 10):1389-93. PubMed ID: 25286946
[TBL] [Abstract][Full Text] [Related]
15. 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.
Demont EH; Bamborough P; Chung CW; Craggs PD; Fallon D; Gordon LJ; Grandi P; Hobbs CI; Hussain J; Jones EJ; Le Gall A; Michon AM; Mitchell DJ; Prinjha RK; Roberts AD; Sheppard RJ; Watson RJ
ACS Med Chem Lett; 2014 Nov; 5(11):1190-5. PubMed ID: 25408830
[TBL] [Abstract][Full Text] [Related]
16. Mutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone Acetylation.
Yan K; Rousseau J; Littlejohn RO; Kiss C; Lehman A; Rosenfeld JA; Stumpel CTR; Stegmann APA; Robak L; Scaglia F; Nguyen TTM; Fu H; Ajeawung NF; Camurri MV; Li L; Gardham A; Panis B; Almannai M; Sacoto MJG; Baskin B; Ruivenkamp C; Xia F; Bi W; ; ; Cho MT; Potjer TP; Santen GWE; Parker MJ; Canham N; McKinnon M; Potocki L; MacKenzie JJ; Roeder ER; Campeau PM; Yang XJ
Am J Hum Genet; 2017 Jan; 100(1):91-104. PubMed ID: 27939640
[TBL] [Abstract][Full Text] [Related]
17. Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer.
Xiang Q; Wang C; Wu T; Zhang C; Hu Q; Luo G; Hu J; Zhuang X; Zou L; Shen H; Wu X; Zhang Y; Kong X; Liu J; Xu Y
J Med Chem; 2022 Jan; 65(1):785-810. PubMed ID: 34962793
[TBL] [Abstract][Full Text] [Related]
18. The BRPF1 bromodomain is a molecular reader of di-acetyllysine.
Obi JO; Lubula MY; Cornilescu G; Henrickson A; McGuire K; Evans CM; Phillips M; Boyson SP; Demeler B; Markley JL; Glass KC
Curr Res Struct Biol; 2020; 2():104-115. PubMed ID: 33554132
[TBL] [Abstract][Full Text] [Related]
19. Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesion.
Appikonda S; Thakkar KN; Shah PK; Dent SYR; Andersen JN; Barton MC
J Biol Chem; 2018 May; 293(19):7476-7485. PubMed ID: 29523690
[TBL] [Abstract][Full Text] [Related]
20. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.
Gechijian LN; Buckley DL; Lawlor MA; Reyes JM; Paulk J; Ott CJ; Winter GE; Erb MA; Scott TG; Xu M; Seo HS; Dhe-Paganon S; Kwiatkowski NP; Perry JA; Qi J; Gray NS; Bradner JE
Nat Chem Biol; 2018 Apr; 14(4):405-412. PubMed ID: 29507391
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
