218 related articles for article (PubMed ID: 35394496)
1. Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR; Ostrander EL; Kukhar O; Mallaney C; Sun J; Haussler E; Celik H; Koh WK; King KY; Gontarz P; Challen GA
Blood Cancer Discov; 2022 May; 3(3):220-239. PubMed ID: 35394496
[TBL] [Abstract][Full Text] [Related]
2. Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling.
Hormaechea-Agulla D; Matatall KA; Le DT; Kain B; Long X; Kus P; Jaksik R; Challen GA; Kimmel M; King KY
Cell Stem Cell; 2021 Aug; 28(8):1428-1442.e6. PubMed ID: 33743191
[TBL] [Abstract][Full Text] [Related]
3. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.
Jeong M; Park HJ; Celik H; Ostrander EL; Reyes JM; Guzman A; Rodriguez B; Lei Y; Lee Y; Ding L; Guryanova OA; Li W; Goodell MA; Challen GA
Cell Rep; 2018 Apr; 23(1):1-10. PubMed ID: 29617651
[TBL] [Abstract][Full Text] [Related]
4. Heterozygous Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool.
Higo T; Suzuki Y; Sato M; Koya J; Mizuno H; Miyauchi M; Masamoto Y; Kataoka K; Sumitomo Y; Tsuruta-Kishino T; Sato T; Kurokawa M
Exp Hematol; 2022 May; 109():45-54. PubMed ID: 35245608
[TBL] [Abstract][Full Text] [Related]
5. Dnmt3a-Mutant Hematopoietic Stem Cell Rewire IFNγ Signaling to Gain Clonal Advantage.
De Dominici M; DeGregori J
Blood Cancer Discov; 2022 May; 3(3):178-180. PubMed ID: 35394495
[TBL] [Abstract][Full Text] [Related]
6. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Tovy A; Reyes JM; Gundry MC; Brunetti L; Lee-Six H; Petljak M; Park HJ; Guzman AG; Rosas C; Jeffries AR; Baple E; Mill J; Crosby AH; Sency V; Xin B; Machado HE; Castillo D; Weitzel JN; Li W; Stratton MR; Campbell PJ; Wang H; Sanders MA; Goodell MA
Cell Stem Cell; 2020 Aug; 27(2):326-335.e4. PubMed ID: 32673568
[TBL] [Abstract][Full Text] [Related]
7. Sowing the Seeds of Clonal Hematopoiesis.
Liggett LA; Voit RA; Sankaran VG
Cell Stem Cell; 2020 Aug; 27(2):195-197. PubMed ID: 32763180
[TBL] [Abstract][Full Text] [Related]
8. Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
Zioni N; Bercovich AA; Chapal-Ilani N; Bacharach T; Rappoport N; Solomon A; Avraham R; Kopitman E; Porat Z; Sacma M; Hartmut G; Scheller M; Muller-Tidow C; Lipka D; Shlush E; Minden M; Kaushansky N; Shlush LI
Nat Commun; 2023 Apr; 14(1):2070. PubMed ID: 37045808
[TBL] [Abstract][Full Text] [Related]
9. Dnmt3a-null hematopoietic stem and progenitor cells expand after busulfan treatment.
Chen J; Matatall KA; Feng X; Hormaechea-Agulla D; Maharjan M; Young N; King KY
Exp Hematol; 2020 Nov; 91():39-45.e2. PubMed ID: 32961298
[TBL] [Abstract][Full Text] [Related]
10. Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis.
SanMiguel JM; Eudy E; Loberg MA; Young KA; Mistry JJ; Mujica KD; Schwartz LS; Stearns TM; Challen GA; Trowbridge JJ
Cancer Discov; 2022 Dec; 12(12):2763-2773. PubMed ID: 36169447
[TBL] [Abstract][Full Text] [Related]
11. Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells.
Schwartz LS; Young KA; Stearns TM; Boyer N; Mujica KD; Trowbridge JJ
Exp Hematol; 2024 Feb; 130():104131. PubMed ID: 38000729
[TBL] [Abstract][Full Text] [Related]
12. Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Nam AS; Dusaj N; Izzo F; Murali R; Myers RM; Mouhieddine TH; Sotelo J; Benbarche S; Waarts M; Gaiti F; Tahri S; Levine R; Abdel-Wahab O; Godley LA; Chaligne R; Ghobrial I; Landau DA
Nat Genet; 2022 Oct; 54(10):1514-1526. PubMed ID: 36138229
[TBL] [Abstract][Full Text] [Related]
13. Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Scheller M; Ludwig AK; Göllner S; Rohde C; Krämer S; Stäble S; Janssen M; Müller JA; He L; Bäumer N; Arnold C; Gerß J; Schönung M; Thiede C; Niederwieser C; Niederwieser D; Serve H; Berdel WE; Thiem U; Hemmerling I; Leuschner F; Plass C; Schlesner M; Zaugg J; Milsom MD; Trumpp A; Pabst C; Lipka DB; Müller-Tidow C
Nat Cancer; 2021 May; 2(5):527-544. PubMed ID: 35122024
[TBL] [Abstract][Full Text] [Related]
14. Clonal hematopoiesis in frequent whole blood donors.
Karpova D
Hematology Am Soc Hematol Educ Program; 2023 Dec; 2023(1):299-304. PubMed ID: 38066913
[TBL] [Abstract][Full Text] [Related]
15. CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease.
Sano S; Oshima K; Wang Y; Katanasaka Y; Sano M; Walsh K
Circ Res; 2018 Jul; 123(3):335-341. PubMed ID: 29728415
[TBL] [Abstract][Full Text] [Related]
16. Metformin reduces the clonal fitness of
Hosseini M; Voisin V; Chegini A; Varesi A; Cathelin S; Ayyathan DM; Liu ACH; Yang Y; Wang V; Maher A; Grignano E; Reisz JA; D'Alessandro A; Young K; Wu Y; Fiumara M; Ferrari S; Naldini L; Gaiti F; Pai S; Schimmer AD; Bader GD; Dick JE; Xie SZ; Trowbridge JJ; Chan SM
Res Sq; 2024 Feb; ():. PubMed ID: 38405837
[TBL] [Abstract][Full Text] [Related]
17. Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.
Loberg MA; Bell RK; Goodwin LO; Eudy E; Miles LA; SanMiguel JM; Young K; Bergstrom DE; Levine RL; Schneider RK; Trowbridge JJ
Leukemia; 2019 Jul; 33(7):1635-1649. PubMed ID: 30692594
[TBL] [Abstract][Full Text] [Related]
18. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Fujino T; Goyama S; Sugiura Y; Inoue D; Asada S; Yamasaki S; Matsumoto A; Yamaguchi K; Isobe Y; Tsuchiya A; Shikata S; Sato N; Morinaga H; Fukuyama T; Tanaka Y; Fukushima T; Takeda R; Yamamoto K; Honda H; Nishimura EK; Furukawa Y; Shibata T; Abdel-Wahab O; Suematsu M; Kitamura T
Nat Commun; 2021 Mar; 12(1):1826. PubMed ID: 33758188
[TBL] [Abstract][Full Text] [Related]
19. Oncostatin M is a Master Regulator of an Inflammatory Network in
Schwartz LS; Young KA; Stearns TM; Boyer N; Mujica KD; Trowbridge JJ
bioRxiv; 2023 Jul; ():. PubMed ID: 37502912
[TBL] [Abstract][Full Text] [Related]
20. Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness.
Ostrander EL; Kramer AC; Mallaney C; Celik H; Koh WK; Fairchild J; Haussler E; Zhang CRC; Challen GA
Stem Cell Reports; 2020 Apr; 14(4):551-560. PubMed ID: 32220332
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
