198 related articles for article (PubMed ID: 35399514)
1. c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
Marín T; Dulcey AE; Campos F; de la Fuente C; Acuña M; Castro J; Pinto C; Yañez MJ; Cortez C; McGrath DW; Sáez PJ; Gorshkov K; Zheng W; Southall N; Carmo-Fonseca M; Marugán J; Alvarez AR; Zanlungo S
Front Cell Dev Biol; 2022; 10():844297. PubMed ID: 35399514
[TBL] [Abstract][Full Text] [Related]
2. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
Long Y; Xu M; Li R; Dai S; Beers J; Chen G; Soheilian F; Baxa U; Wang M; Marugan JJ; Muro S; Li Z; Brady R; Zheng W
Stem Cells Transl Med; 2016 Dec; 5(12):1644-1655. PubMed ID: 27484861
[TBL] [Abstract][Full Text] [Related]
3. Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease.
Pascua-Maestro R; Corraliza-Gomez M; Fadrique-Rojo C; Ledesma MD; Schuchman EH; Sanchez D; Ganfornina MD
Neurobiol Dis; 2020 Oct; 144():105046. PubMed ID: 32798728
[TBL] [Abstract][Full Text] [Related]
4. Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A.
Carsana EV; Lunghi G; Prioni S; Mauri L; Loberto N; Prinetti A; Zucca FA; Bassi R; Sonnino S; Chiricozzi E; Duga S; Straniero L; Asselta R; Soldà G; Samarani M; Aureli M
J Mol Neurosci; 2022 Jul; 72(7):1482-1499. PubMed ID: 35727525
[TBL] [Abstract][Full Text] [Related]
5. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A.
Gabandé-Rodríguez E; Boya P; Labrador V; Dotti CG; Ledesma MD
Cell Death Differ; 2014 Jun; 21(6):864-75. PubMed ID: 24488099
[TBL] [Abstract][Full Text] [Related]
6. Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease.
Pérez-Cañamás A; Benvegnù S; Rueda CB; Rábano A; Satrústegui J; Ledesma MD
Mol Psychiatry; 2017 May; 22(5):711-723. PubMed ID: 27620840
[TBL] [Abstract][Full Text] [Related]
7. Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.
Contreras PS; Gonzalez-Zuñiga M; González-Hódar L; Yáñez MJ; Dulcey A; Marugan J; Seto E; Alvarez AR; Zanlungo S
Biochim Biophys Acta; 2016 Feb; 1859(2):269-79. PubMed ID: 26603102
[TBL] [Abstract][Full Text] [Related]
8. Nanoreporter Identifies Lysosomal Storage Disease Lipid Accumulation Intracranially.
Antman-Passig M; Yaari Z; Goerzen D; Parikh R; Chatman S; Komer LE; Chen C; Grabarnik E; Mathieu M; Haimovitz-Friedman A; Heller DA
Nano Lett; 2023 Dec; 23(23):10687-10695. PubMed ID: 37889874
[TBL] [Abstract][Full Text] [Related]
9. Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease.
Alvarez AR; Klein A; Castro J; Cancino GI; Amigo J; Mosqueira M; Vargas LM; Yévenes LF; Bronfman FC; Zanlungo S
FASEB J; 2008 Oct; 22(10):3617-27. PubMed ID: 18591368
[TBL] [Abstract][Full Text] [Related]
10. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
[TBL] [Abstract][Full Text] [Related]
11. Lipid-induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders.
Gabandé-Rodríguez E; Pérez-Cañamás A; Soto-Huelin B; Mitroi DN; Sánchez-Redondo S; Martínez-Sáez E; Venero C; Peinado H; Ledesma MD
EMBO J; 2019 Jan; 38(2):. PubMed ID: 30530526
[TBL] [Abstract][Full Text] [Related]
12. An Early-Onset Neuronopathic Form of Acid Sphingomyelinase Deficiency: A SMPD1 p.C133Y Mutation in the Saposin Domain of Acid Sphingomyelinase.
Ota S; Noguchi A; Kondo D; Nakajima Y; Ito T; Arai H; Takahashi T
Tohoku J Exp Med; 2020 Jan; 250(1):5-11. PubMed ID: 31941852
[TBL] [Abstract][Full Text] [Related]
13. Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease.
Torres S; Balboa E; Zanlungo S; Enrich C; Garcia-Ruiz C; Fernandez-Checa JC
Front Physiol; 2017; 8():982. PubMed ID: 29249985
[TBL] [Abstract][Full Text] [Related]
14. Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.
Argüello G; Balboa E; Tapia PJ; Castro J; Yañez MJ; Mattar P; Pulgar R; Zanlungo S
Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33921734
[TBL] [Abstract][Full Text] [Related]
15. Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann-Pick A disease.
Dodge JC; Clarke J; Treleaven CM; Taksir TV; Griffiths DA; Yang W; Fidler JA; Passini MA; Karey KP; Schuchman EH; Cheng SH; Shihabuddin LS
Exp Neurol; 2009 Feb; 215(2):349-57. PubMed ID: 19059399
[TBL] [Abstract][Full Text] [Related]
16. Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice.
Marín T; Contreras P; Castro JF; Chamorro D; Balboa E; Bosch-Morató M; Muñoz FJ; Alvarez AR; Zanlungo S
Nutrients; 2014 Jul; 6(8):3000-17. PubMed ID: 25079853
[TBL] [Abstract][Full Text] [Related]
17. Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y; Chen J; Wu X; Gui C; Mao K; Zou F; Li W
Toxicol Sci; 2018 Sep; 165(1):232-243. PubMed ID: 30165626
[TBL] [Abstract][Full Text] [Related]
18. Accurate differentiation of neuronopathic and nonneuronopathic forms of Niemann-Pick disease by evaluation of the effective residual lysosomal sphingomyelinase activity in intact cells.
Graber D; Salvayre R; Levade T
J Neurochem; 1994 Sep; 63(3):1060-8. PubMed ID: 8051547
[TBL] [Abstract][Full Text] [Related]
19. c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder.
Contreras PS; Tapia PJ; González-Hódar L; Peluso I; Soldati C; Napolitano G; Matarese M; Heras ML; Valls C; Martinez A; Balboa E; Castro J; Leal N; Platt FM; Sobota A; Winter D; Klein AD; Medina DL; Ballabio A; Alvarez AR; Zanlungo S
iScience; 2020 Nov; 23(11):101691. PubMed ID: 33163944
[TBL] [Abstract][Full Text] [Related]
20. AAV vector-mediated correction of brain pathology in a mouse model of Niemann-Pick A disease.
Passini MA; Macauley SL; Huff MR; Taksir TV; Bu J; Wu IH; Piepenhagen PA; Dodge JC; Shihabuddin LS; O'Riordan CR; Schuchman EH; Stewart GR
Mol Ther; 2005 May; 11(5):754-62. PubMed ID: 15851014
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]