These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
148 related articles for article (PubMed ID: 35404139)
1. Elimination of Off-Target Effect by Chemical Modification of 5'-End of siRNA. Shiohama Y; Fujita R; Sonokawa M; Hisano M; Kotake Y; Krstic-Demonacos M; Demonacos C; Kashiwazaki G; Kitayama T; Fujii M Nucleic Acid Ther; 2022 Oct; 32(5):438-447. PubMed ID: 35404139 [TBL] [Abstract][Full Text] [Related]
2. Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. Chen PY; Weinmann L; Gaidatzis D; Pei Y; Zavolan M; Tuschl T; Meister G RNA; 2008 Feb; 14(2):263-74. PubMed ID: 18094121 [TBL] [Abstract][Full Text] [Related]
3. Investigation of Strand-Selective Interaction of SNA-Modified siRNA with AGO2-MID. Kamiya Y; Takeyama Y; Mizuno T; Satoh F; Asanuma H Int J Mol Sci; 2020 Jul; 21(15):. PubMed ID: 32717920 [TBL] [Abstract][Full Text] [Related]
4. Effect of siRNA with an asymmetric RNA/dTdT overhang on RNA interference activity. Park JH; Hong SW; Yun S; Lee DK; Shin C Nucleic Acid Ther; 2014 Oct; 24(5):364-71. PubMed ID: 25211666 [TBL] [Abstract][Full Text] [Related]
5. Competition potency of siRNA is specified by the 5'-half sequence of the guide strand. Yoo JW; Kim S; Lee DK Biochem Biophys Res Commun; 2008 Feb; 367(1):78-83. PubMed ID: 18164261 [TBL] [Abstract][Full Text] [Related]
6. Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency. Mobergslien A; Sioud M Methods Mol Biol; 2020; 2115():163-170. PubMed ID: 32006400 [TBL] [Abstract][Full Text] [Related]
7. siRNA potency enhancement via chemical modifications of nucleotide bases at the 5'-end of the siRNA guide strand. Shinohara F; Oashi T; Harumoto T; Nishikawa T; Takayama Y; Miyagi H; Takahashi Y; Nakajima T; Sawada T; Koda Y; Makino A; Sato A; Hamaguchi K; Suzuki M; Yamamoto J; Tomari Y; Saito JI RNA; 2021 Feb; 27(2):163-173. PubMed ID: 33177188 [TBL] [Abstract][Full Text] [Related]
8. Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection. Sano M; Sierant M; Miyagishi M; Nakanishi M; Takagi Y; Sutou S Nucleic Acids Res; 2008 Oct; 36(18):5812-21. PubMed ID: 18782830 [TBL] [Abstract][Full Text] [Related]
9. A systematic study on the influence of thermodynamic asymmetry of 5'-ends of siRNA duplexes in relation to their silencing potency. Lisowiec-Wąchnicka J; Bartyś N; Pasternak A Sci Rep; 2019 Feb; 9(1):2477. PubMed ID: 30792489 [TBL] [Abstract][Full Text] [Related]
10. Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex. Datta D; Theile CS; Wassarman K; Qin J; Racie T; Schmidt K; Jiang Y; Sigel R; Janas MM; Egli M; Manoharan M Chem Commun (Camb); 2023 May; 59(42):6347-6350. PubMed ID: 37144553 [TBL] [Abstract][Full Text] [Related]
11. Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs. Hamada M; Ohtsuka T; Kawaida R; Koizumi M; Morita K; Furukawa H; Imanishi T; Miyagishi M; Taira K Antisense Nucleic Acid Drug Dev; 2002 Oct; 12(5):301-9. PubMed ID: 12477280 [TBL] [Abstract][Full Text] [Related]
12. Modification of the siRNA passenger strand by 5-nitroindole dramatically reduces its off-target effects. Zhang J; Zheng J; Lu C; Du Q; Liang Z; Xi Z Chembiochem; 2012 Sep; 13(13):1940-5. PubMed ID: 22887813 [TBL] [Abstract][Full Text] [Related]
13. Relative Quantification of siRNA Strand Loading into Ago2 for Design of Highly Active siRNAs. Angart PA; Adu-Berchie K; Carlson RJ; Vocelle DB; Chan C; Walton SP Methods Mol Biol; 2019; 1974():41-56. PubMed ID: 31098994 [TBL] [Abstract][Full Text] [Related]
15. Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila. Preall JB; He Z; Gorra JM; Sontheimer EJ Curr Biol; 2006 Mar; 16(5):530-5. PubMed ID: 16527750 [TBL] [Abstract][Full Text] [Related]
16. Mechanistic analysis of the enhanced RNAi activity by 6-mCEPh-purine at the 5' end of the siRNA guide strand. Brechin V; Shinohara F; Saito JI; Seitz H; Tomari Y RNA; 2021 Feb; 27(2):151-162. PubMed ID: 33177187 [TBL] [Abstract][Full Text] [Related]
18. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Rand TA; Petersen S; Du F; Wang X Cell; 2005 Nov; 123(4):621-9. PubMed ID: 16271385 [TBL] [Abstract][Full Text] [Related]