These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 35405106)

  • 1. Synergistic FRET assays for drug discovery targeting RyR2 channels.
    Rebbeck R; Ginsburg KS; Ko CY; Fasoli A; Rusch K; Cai GF; Dong X; Thomas DD; Bers DM; Cornea RL
    J Mol Cell Cardiol; 2022 Jul; 168():13-23. PubMed ID: 35405106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State.
    Svensson B; Nitu FR; Rebbeck RT; McGurran LM; Oda T; Thomas DD; Bers DM; Cornea RL
    Int J Mol Sci; 2023 Aug; 24(16):. PubMed ID: 37628726
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding.
    Oda T; Yang Y; Nitu FR; Svensson B; Lu X; Fruen BR; Cornea RL; Bers DM
    Circ Res; 2013 Feb; 112(3):487-97. PubMed ID: 23233753
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.
    Oda T; Yang Y; Uchinoumi H; Thomas DD; Chen-Izu Y; Kato T; Yamamoto T; Yano M; Cornea RL; Bers DM
    J Mol Cell Cardiol; 2015 Aug; 85():240-8. PubMed ID: 26092277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.
    Guo T; Fruen BR; Nitu FR; Nguyen TD; Yang Y; Cornea RL; Bers DM
    Biophys J; 2011 Nov; 101(9):2170-7. PubMed ID: 22067155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State.
    Svensson B; Nitu FR; Rebbeck RT; McGurran LM; Oda T; Thomas DD; Bers DM; Cornea RL
    bioRxiv; 2023 Jul; ():. PubMed ID: 37461514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.
    Uchinoumi H; Yang Y; Oda T; Li N; Alsina KM; Puglisi JL; Chen-Izu Y; Cornea RL; Wehrens XHT; Bers DM
    J Mol Cell Cardiol; 2016 Sep; 98():62-72. PubMed ID: 27318036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FRET-based trilateration of probes bound within functional ryanodine receptors.
    Svensson B; Oda T; Nitu FR; Yang Y; Cornea I; Chen-Izu Y; Fessenden JD; Bers DM; Thomas DD; Cornea RL
    Biophys J; 2014 Nov; 107(9):2037-48. PubMed ID: 25418089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.
    Yang Y; Guo T; Oda T; Chakraborty A; Chen L; Uchinoumi H; Knowlton AA; Fruen BR; Cornea RL; Meissner G; Bers DM
    Circ Res; 2014 Jan; 114(2):295-306. PubMed ID: 24186966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels.
    Rebbeck RT; Essawy MM; Nitu FR; Grant BD; Gillispie GD; Thomas DD; Bers DM; Cornea RL
    SLAS Discov; 2017 Feb; 22(2):176-186. PubMed ID: 27760856
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.
    Ono M; Yano M; Hino A; Suetomi T; Xu X; Susa T; Uchinoumi H; Tateishi H; Oda T; Okuda S; Doi M; Kobayashi S; Yamamoto T; Koseki N; Kyushiki H; Ikemoto N; Matsuzaki M
    Cardiovasc Res; 2010 Sep; 87(4):609-17. PubMed ID: 20388639
    [TBL] [Abstract][Full Text] [Related]  

  • 12. S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.
    Rebbeck RT; Nitu FR; Rohde D; Most P; Bers DM; Thomas DD; Cornea RL
    J Biol Chem; 2016 Jul; 291(30):15896-907. PubMed ID: 27226555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts.
    Tateishi H; Yano M; Mochizuki M; Suetomi T; Ono M; Xu X; Uchinoumi H; Okuda S; Oda T; Kobayashi S; Yamamoto T; Ikeda Y; Ohkusa T; Ikemoto N; Matsuzaki M
    Cardiovasc Res; 2009 Feb; 81(3):536-45. PubMed ID: 18996969
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2.
    Klipp RC; Li N; Wang Q; Word TA; Sibrian-Vazquez M; Strongin RM; Wehrens XHT; Abramson JJ
    Heart Rhythm; 2018 Apr; 15(4):578-586. PubMed ID: 29248564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening.
    Zhang J; Singh DP; Ko CY; Nikolaienko R; Wong King Yuen SM; Schwarz JA; Treinen LM; Tung CC; Rožman K; Svensson B; Aldrich CC; Zima AV; Thomas DD; Bers DM; Launikonis BS; Van Petegem F; Cornea RL
    J Biol Chem; 2022 Jan; 298(1):101412. PubMed ID: 34793835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.
    Ai X; Curran JW; Shannon TR; Bers DM; Pogwizd SM
    Circ Res; 2005 Dec; 97(12):1314-22. PubMed ID: 16269653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Toll-like receptor 4-induced ryanodine receptor 2 oxidation and sarcoplasmic reticulum Ca
    Yang J; Zhang R; Jiang X; Lv J; Li Y; Ye H; Liu W; Wang G; Zhang C; Zheng N; Dong M; Wang Y; Chen P; Santosh K; Jiang Y; Liu J
    J Biol Chem; 2018 Jan; 293(3):794-807. PubMed ID: 29150444
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes.
    Yang Z; Ikemoto N; Lamb GD; Steele DS
    Cardiovasc Res; 2006 Jun; 70(3):475-85. PubMed ID: 16624262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
    Guo T; Cornea RL; Huke S; Camors E; Yang Y; Picht E; Fruen BR; Bers DM
    Circ Res; 2010 Jun; 106(11):1743-52. PubMed ID: 20431056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
    Shan J; Xie W; Betzenhauser M; Reiken S; Chen BX; Wronska A; Marks AR
    Circ Res; 2012 Aug; 111(6):708-17. PubMed ID: 22828895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.