BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 35409154)

  • 1. Overcoming Steroid Resistance in Pediatric Acute Lymphoblastic Leukemia-The State-of-the-Art Knowledge and Future Prospects.
    Kośmider K; Karska K; Kozakiewicz A; Lejman M; Zawitkowska J
    Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35409154
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
    van der Zwet JCG; Buijs-Gladdines JGCAM; Cordo' V; Debets DO; Smits WK; Chen Z; Dylus J; Zaman GJR; Altelaar M; Oshima K; Bornhauser B; Bourquin JP; Cools J; Ferrando AA; Vormoor J; Pieters R; Vormoor B; Meijerink JPP
    Leukemia; 2021 Dec; 35(12):3394-3405. PubMed ID: 34007050
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.
    Li Y; Buijs-Gladdines JG; Canté-Barrett K; Stubbs AP; Vroegindeweij EM; Smits WK; van Marion R; Dinjens WN; Horstmann M; Kuiper RP; Buijsman RC; Zaman GJ; van der Spek PJ; Pieters R; Meijerink JP
    PLoS Med; 2016 Dec; 13(12):e1002200. PubMed ID: 27997540
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM.
    Rambal AA; Panaguiton ZL; Kramer L; Grant S; Harada H
    Leukemia; 2009 Oct; 23(10):1744-54. PubMed ID: 19404317
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.
    Serafin V; Capuzzo G; Milani G; Minuzzo SA; Pinazza M; Bortolozzi R; Bresolin S; Porcù E; Frasson C; Indraccolo S; Basso G; Accordi B
    Blood; 2017 Dec; 130(25):2750-2761. PubMed ID: 29101238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting steroid resistance in T-cell acute lymphoblastic leukemia.
    De Smedt R; Morscio J; Goossens S; Van Vlierberghe P
    Blood Rev; 2019 Nov; 38():100591. PubMed ID: 31353059
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the mitogen-activated protein kinase-extracellular signal-regulated kinase pathway in childhood B-cell acute lymphoblastic leukemia.
    Pillai PM; Mallory N; Pierro J; Saliba J; Newman D; Hu J; Bhatla T; Raetz E; Carroll WL; Evensen NA
    Pediatr Blood Cancer; 2022 Oct; 69(10):e29771. PubMed ID: 35593589
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [P38 mitogen-activated protein kinase mediates glucocorticoid receptor function induced by dexamethasone in acute lymphoblastic leukemia cells].
    He L; Li D; Hou KZ; Liu YP
    Zhonghua Er Ke Za Zhi; 2007 Sep; 45(9):687-91. PubMed ID: 18021564
    [TBL] [Abstract][Full Text] [Related]  

  • 10. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.
    Delgado-Martin C; Meyer LK; Huang BJ; Shimano KA; Zinter MS; Nguyen JV; Smith GA; Taunton J; Winter SS; Roderick JR; Kelliher MA; Horton TM; Wood BL; Teachey DT; Hermiston ML
    Leukemia; 2017 Dec; 31(12):2568-2576. PubMed ID: 28484265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TCF7L2 activated HOXA-AS2 decreased the glucocorticoid sensitivity in acute lymphoblastic leukemia through regulating HOXA3/EGFR/Ras/Raf/MEK/ERK pathway.
    Zhao Q; Zhao S; Li J; Zhang H; Qian C; Wang H; Liu J; Zhao Y
    Biomed Pharmacother; 2019 Jan; 109():1640-1649. PubMed ID: 30551418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Stam RW; Den Boer ML; Schneider P; de Boer J; Hagelstein J; Valsecchi MG; de Lorenzo P; Sallan SE; Brady HJ; Armstrong SA; Pieters R
    Blood; 2010 Feb; 115(5):1018-25. PubMed ID: 19965632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.
    Möricke A; Zimmermann M; Valsecchi MG; Stanulla M; Biondi A; Mann G; Locatelli F; Cazzaniga G; Niggli F; Aricò M; Bartram CR; Attarbaschi A; Silvestri D; Beier R; Basso G; Ratei R; Kulozik AE; Lo Nigro L; Kremens B; Greiner J; Parasole R; Harbott J; Caruso R; von Stackelberg A; Barisone E; Rössig C; Conter V; Schrappe M
    Blood; 2016 Apr; 127(17):2101-12. PubMed ID: 26888258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Philadelphia chromosome-positive (Ph+) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome.
    Schrappe M; Aricò M; Harbott J; Biondi A; Zimmermann M; Conter V; Reiter A; Valsecchi MG; Gadner H; Basso G; Bartram CR; Lampert F; Riehm H; Masera G
    Blood; 1998 Oct; 92(8):2730-41. PubMed ID: 9763557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia.
    Case M; Matheson E; Minto L; Hassan R; Harrison CJ; Bown N; Bailey S; Vormoor J; Hall AG; Irving JA
    Cancer Res; 2008 Aug; 68(16):6803-9. PubMed ID: 18701506
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.
    Heidari N; Miller AV; Hicks MA; Marking CB; Harada H
    Cell Death Dis; 2012 Jul; 3(7):e349. PubMed ID: 22825467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Low-dose anisomycin sensitizes glucocorticoid-resistant T-acute lymphoblastic leukemia CEM-C1 cells to dexamethasone-induced apoptosis through activation of glucocorticoid receptor and p38-MAPK/JNK.
    Liu Y; Ge J; Li Q; Guo X; Gu L; Ma ZG; Li XH; Zhu YP
    Leuk Lymphoma; 2014 Sep; 55(9):2179-88. PubMed ID: 24597985
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma.
    Landmann E; Burkhardt B; Zimmermann M; Meyer U; Woessmann W; Klapper W; Wrobel G; Rosolen A; Pillon M; Escherich G; Attarbaschi A; Beishuizen A; Mellgren K; Wynn R; Ratei R; Plesa A; Schrappe M; Reiter A; Bergeron C; Patte C; Bertrand Y
    Haematologica; 2017 Dec; 102(12):2086-2096. PubMed ID: 28983060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.
    Matheson EC; Thomas H; Case M; Blair H; Jackson RK; Masic D; Veal G; Halsey C; Newell DR; Vormoor J; Irving JAE
    Haematologica; 2019 Sep; 104(9):1804-1811. PubMed ID: 30655370
    [TBL] [Abstract][Full Text] [Related]  

  • 20. STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of
    Van der Zwet JCG; Cordo' V; Buijs-Gladdines JGCAM; Hagelaar R; Smits WK; Vroegindeweij E; Graus LTM; Poort V; Nulle M; Pieters R; Meijerink JPP
    Haematologica; 2023 Mar; 108(3):732-746. PubMed ID: 35734930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.