BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 35411506)

  • 41. Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates.
    Nagaya Y; Nozaki Y; Kobayashi K; Takenaka O; Nakatani Y; Kusano K; Yoshimura T; Kusuhara H
    Drug Metab Pharmacokinet; 2014; 29(5):419-26. PubMed ID: 24806821
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution.
    Langthaler K; Jones CR; Saaby L; Bundgaard C; Brodin B
    Fluids Barriers CNS; 2024 Jan; 21(1):11. PubMed ID: 38273301
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.
    Uchida Y; Wakayama K; Ohtsuki S; Chiba M; Ohe T; Ishii Y; Terasaki T
    J Pharmacol Exp Ther; 2014 Sep; 350(3):578-88. PubMed ID: 24947467
    [TBL] [Abstract][Full Text] [Related]  

  • 44. QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, K
    Dolgikh E; Watson IA; Desai PV; Sawada GA; Morton S; Jones TM; Raub TJ
    J Chem Inf Model; 2016 Nov; 56(11):2225-2233. PubMed ID: 27684523
    [TBL] [Abstract][Full Text] [Related]  

  • 45. In silico prediction of unbound brain-to-plasma concentration ratio using machine learning algorithms.
    Chen H; Winiwarter S; Fridén M; Antonsson M; Engkvist O
    J Mol Graph Model; 2011 Aug; 29(8):985-95. PubMed ID: 21571561
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The brain slice method for studying drug distribution in the CNS.
    Loryan I; Fridén M; Hammarlund-Udenaes M
    Fluids Barriers CNS; 2013 Jan; 10(1):6. PubMed ID: 23336814
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Active-site concentrations of chemicals - are they a better predictor of effect than plasma/organ/tissue concentrations?
    Hammarlund-Udenaes M
    Basic Clin Pharmacol Toxicol; 2010 Mar; 106(3):215-20. PubMed ID: 20050843
    [TBL] [Abstract][Full Text] [Related]  

  • 48.
    Zhang W; Oh JH; Zhang W; Aldrich CC; Sirianni RW; Elmquist WF
    J Pharmacol Exp Ther; 2024 Apr; ():. PubMed ID: 38670802
    [TBL] [Abstract][Full Text] [Related]  

  • 49. CNS Penetration of Cyclophosphamide and Metabolites in Mice Bearing Group 3 Medulloblastoma and Non-Tumor Bearing Mice.
    Campagne O; Davis A; Zhong B; Nair S; Haberman V; T Patel Y; Janke L; F Roussel M; Stewart C
    J Pharm Pharm Sci; 2019; 22(1):612-629. PubMed ID: 31815662
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Insight into tissue unbound concentration: utility in drug discovery and development.
    Mariappan TT; Mandlekar S; Marathe P
    Curr Drug Metab; 2013 Mar; 14(3):324-40. PubMed ID: 23167621
    [TBL] [Abstract][Full Text] [Related]  

  • 51. In Vivo Quantitative Understanding of PEGylated Liposome's Influence on Brain Delivery of Diphenhydramine.
    Hu Y; Gaillard PJ; Rip J; de Lange ECM; Hammarlund-Udenaes M
    Mol Pharm; 2018 Dec; 15(12):5493-5500. PubMed ID: 30376346
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.
    Uchida Y; Ohtsuki S; Kamiie J; Terasaki T
    J Pharmacol Exp Ther; 2011 Nov; 339(2):579-88. PubMed ID: 21828264
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Morphine brain pharmacokinetics at very low concentrations studied with accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.
    Sadiq MW; Salehpour M; Forsgard N; Possnert G; Hammarlund-Udenaes M
    Drug Metab Dispos; 2011 Feb; 39(2):174-9. PubMed ID: 21059857
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer.
    Samala R; Thorsheim HR; Goda S; Taskar K; Gril B; Steeg PS; Smith QR
    Pharm Res; 2016 Dec; 33(12):2904-2919. PubMed ID: 27541873
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology.
    Gustafsson S; Lindström V; Ingelsson M; Hammarlund-Udenaes M; Syvänen S
    Neuropharmacology; 2018 Jan; 128():482-491. PubMed ID: 28797721
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: K(p), K(p,u), and K(p,uu).
    Gupta A; Chatelain P; Massingham R; Jonsson EN; Hammarlund-Udenaes M
    Drug Metab Dispos; 2006 Feb; 34(2):318-23. PubMed ID: 16303872
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Are capecitabine and the active metabolite 5-Fu CNS penetrable to treat breast cancer brain metastasis?
    Zhang J; Zhang L; Yan Y; Li S; Xie L; Zhong W; Lv J; Zhang X; Bai Y; Cheng Z
    Drug Metab Dispos; 2015 Mar; 43(3):411-7. PubMed ID: 25547867
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Pharmacokinetics of pericyte involvement in small-molecular drug transport across the blood-brain barrier.
    Mihajlica N; Betsholtz C; Hammarlund-Udenaes M
    Eur J Pharm Sci; 2018 Sep; 122():77-84. PubMed ID: 29933077
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening.
    Kadoguchi M; Arakawa H; Honda R; Hotta K; Shirasaka Y; Deguchi Y; Tamai I
    Pharm Res; 2022 Jul; 39(7):1549-1559. PubMed ID: 35314999
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Perspectives on Nanodelivery to the Brain: Prerequisites for Successful Brain Treatment.
    Hu Y; Hammarlund-Udenaes M
    Mol Pharm; 2020 Nov; 17(11):4029-4039. PubMed ID: 33064009
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.