These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 35412314)

  • 41. An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery.
    Parrott N; Paquereau N; Coassolo P; Lavé T
    J Pharm Sci; 2005 Oct; 94(10):2327-43. PubMed ID: 16136543
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Evaluating the Use of Graph Neural Networks and Transfer Learning for Oral Bioavailability Prediction.
    Ng SSS; Lu Y
    J Chem Inf Model; 2023 Aug; 63(16):5035-5044. PubMed ID: 37582507
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Prediction of Compound Plasma Concentration-Time Profiles in Mice Using Random Forest.
    Handa K; Wright P; Yoshimura S; Kageyama M; Iijima T; Bender A
    Mol Pharm; 2023 Jun; 20(6):3060-3072. PubMed ID: 37096989
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Advances in Predictions of Oral Bioavailability of Candidate Drugs in Man with New Machine Learning Methodology.
    Fagerholm U; Hellberg S; Spjuth O
    Molecules; 2021 Apr; 26(9):. PubMed ID: 33925103
    [TBL] [Abstract][Full Text] [Related]  

  • 45. A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans.
    Li Y; Wang Z; Li Y; Du J; Gao X; Li Y; Lai L
    Pharm Res; 2024 Jun; ():. PubMed ID: 38918309
    [TBL] [Abstract][Full Text] [Related]  

  • 46.
    Fagerholm U; Hellberg S; Alvarsson J; Spjuth O
    Xenobiotica; 2022 Feb; 52(2):113-118. PubMed ID: 35238270
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.
    Yamazaki S; Skaptason J; Romero D; Vekich S; Jones HM; Tan W; Wilner KD; Koudriakova T
    Drug Metab Dispos; 2011 Mar; 39(3):383-93. PubMed ID: 21098644
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Estimation of drug exposure by machine learning based on simulations from published pharmacokinetic models: The example of tacrolimus.
    Woillard JB; Labriffe M; Prémaud A; Marquet P
    Pharmacol Res; 2021 May; 167():105578. PubMed ID: 33775863
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Modelling and PBPK simulation in drug discovery.
    Jones HM; Gardner IB; Watson KJ
    AAPS J; 2009 Mar; 11(1):155-66. PubMed ID: 19280352
    [TBL] [Abstract][Full Text] [Related]  

  • 50. In silico drug absorption tract: An agent-based biomimetic model for human oral drug absorption.
    Deng J; Jhandey A; Zhu X; Yang Z; Yik KFP; Zuo Z; Lam TN
    PLoS One; 2018; 13(8):e0203361. PubMed ID: 30169515
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery.
    Van den Bergh A; Sinha V; Gilissen R; Straetemans R; Wuyts K; Morrison D; Bijnens L; Mackie C
    Clin Pharmacokinet; 2011 Aug; 50(8):505-17. PubMed ID: 21740074
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Integration of In Silico Pharmacokinetic Modeling Approaches Into In Vitro Dissolution Profiles to Predict Bioavailability of a Poorly Soluble Compound.
    Kato T; Watanabe T; Nakamura K; Ando S
    J Pharm Sci; 2019 Nov; 108(11):3723-3728. PubMed ID: 31278915
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Technologies for Measuring Pharmacokinetic Profiles.
    Heller AA; Lockwood SY; Janes TM; Spence DM
    Annu Rev Anal Chem (Palo Alto Calif); 2018 Jun; 11(1):79-100. PubMed ID: 29324183
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.
    Chen Y; Jin JY; Mukadam S; Malhi V; Kenny JR
    Biopharm Drug Dispos; 2012 Mar; 33(2):85-98. PubMed ID: 22228214
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.
    Poulin P; Theil FP
    J Pharm Sci; 2002 May; 91(5):1358-70. PubMed ID: 11977112
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Evaluation of an integrated in vitro-in silico PBPK (physiologically based pharmacokinetic) model to provide estimates of human bioavailability.
    Cai H; Stoner C; Reddy A; Freiwald S; Smith D; Winters R; Stankovic C; Surendran N
    Int J Pharm; 2006 Feb; 308(1-2):133-9. PubMed ID: 16352407
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Identification of intestinal loss of a drug through physiologically based pharmacokinetic simulation of plasma concentration-time profiles.
    Peters SA
    Clin Pharmacokinet; 2008; 47(4):245-59. PubMed ID: 18336054
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Model-based Target Pharmacology Assessment (mTPA): An Approach Using PBPK/PD Modeling and Machine Learning to Design Medicinal Chemistry and DMPK Strategies in Early Drug Discovery.
    Chen EP; Bondi RW; Michalski PJ
    J Med Chem; 2021 Mar; 64(6):3185-3196. PubMed ID: 33719432
    [TBL] [Abstract][Full Text] [Related]  

  • 59. N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerations.
    He K; Qian M; Wong H; Bai SA; He B; Brogdon B; Grace JE; Xin B; Wu J; Ren SX; Zeng H; Deng Y; Graden DM; Olah TV; Unger SE; Luettgen JM; Knabb RM; Pinto DJ; Lam PY; Duan J; Wexler RR; Decicco CP; Christ DD; Grossman SJ
    J Pharm Sci; 2008 Jul; 97(7):2568-80. PubMed ID: 17914718
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Prediction of drug disposition on the basis of its chemical structure.
    Stepensky D
    Clin Pharmacokinet; 2013 Jun; 52(6):415-31. PubMed ID: 23463353
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.