These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 35414100)

  • 1. Flap endonuclease 1 and DNA-PKcs synergistically participate in stabilizing replication fork to encounter replication stress in glioma cells.
    Zhang J; Chen M; Pang Y; Cheng M; Huang B; Xu S; Liu M; Lian H; Zhong C
    J Exp Clin Cancer Res; 2022 Apr; 41(1):140. PubMed ID: 35414100
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.
    Ward TA; McHugh PJ; Durant ST
    PLoS One; 2017; 12(6):e0179278. PubMed ID: 28628639
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.
    Guo E; Ishii Y; Mueller J; Srivatsan A; Gahman T; Putnam CD; Wang JYJ; Kolodner RD
    Proc Natl Acad Sci U S A; 2020 Aug; 117(32):19415-19424. PubMed ID: 32719125
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
    Xu X; Shi R; Zheng L; Guo Z; Wang L; Zhou M; Zhao Y; Tian B; Truong K; Chen Y; Shen B; Hua Y; Xu H
    J Mol Cell Biol; 2018 Oct; 10(5):460-474. PubMed ID: 30184152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA-PKcs promotes fork reversal and chemoresistance.
    Dibitetto D; Marshall S; Sanchi A; Liptay M; Badar J; Lopes M; Rottenberg S; Smolka MB
    Mol Cell; 2022 Oct; 82(20):3932-3942.e6. PubMed ID: 36130596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.
    He L; Zhang Y; Sun H; Jiang F; Yang H; Wu H; Zhou T; Hu S; Kathera CS; Wang X; Chen H; Li H; Shen B; Zhu Y; Guo Z
    EBioMedicine; 2016 Dec; 14():32-43. PubMed ID: 27852524
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
    Hromas R; Kim HS; Sidhu G; Williamson E; Jaiswal A; Totterdale TA; Nole J; Lee SH; Nickoloff JA; Kong KY
    Breast Cancer Res; 2017 Nov; 19(1):122. PubMed ID: 29145865
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
    Mengwasser KE; Adeyemi RO; Leng Y; Choi MY; Clairmont C; D'Andrea AD; Elledge SJ
    Mol Cell; 2019 Mar; 73(5):885-899.e6. PubMed ID: 30686591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flap endonuclease 1 contributes to telomere stability.
    Saharia A; Guittat L; Crocker S; Lim A; Steffen M; Kulkarni S; Stewart SA
    Curr Biol; 2008 Apr; 18(7):496-500. PubMed ID: 18394896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FEN1 ensures telomere stability by facilitating replication fork re-initiation.
    Saharia A; Teasley DC; Duxin JP; Dao B; Chiappinelli KB; Stewart SA
    J Biol Chem; 2010 Aug; 285(35):27057-27066. PubMed ID: 20551483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.
    Przetocka S; Porro A; Bolck HA; Walker C; Lezaja A; Trenner A; von Aesch C; Himmels SF; D'Andrea AD; Ceccaldi R; Altmeyer M; Sartori AA
    Mol Cell; 2018 Nov; 72(3):568-582.e6. PubMed ID: 30344097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Post-translational Modifications by Acyl Groups Regulate FEN1's Activities and Play Essential Roles in Cell Proliferation and DNA Repair.
    Xiao Y; Yin M; Wang Y; Shi R; Mao S; Hua Y; Xu H
    Protein Pept Lett; 2023; 30(7):597-607. PubMed ID: 37254539
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy.
    Yang F; Hu Z; Guo Z
    Biomolecules; 2022 Jul; 12(7):. PubMed ID: 35883563
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks.
    Schilling EM; Scherer M; Rothemund F; Stamminger T
    PLoS Pathog; 2021 Mar; 17(3):e1009460. PubMed ID: 33770148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
    Shi R; Wang Y; Gao Y; Xu X; Mao S; Xiao Y; Song S; Wang L; Tian B; Zhao Y; Hua Y; Xu H
    Am J Physiol Cell Physiol; 2020 Oct; 319(4):C657-C666. PubMed ID: 32783654
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Flap endonuclease 1: a central component of DNA metabolism.
    Liu Y; Kao HI; Bambara RA
    Annu Rev Biochem; 2004; 73():589-615. PubMed ID: 15189154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand.
    Teasley DC; Parajuli S; Nguyen M; Moore HR; Alspach E; Lock YJ; Honaker Y; Saharia A; Piwnica-Worms H; Stewart SA
    J Biol Chem; 2015 Jun; 290(24):15133-45. PubMed ID: 25922071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25773776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
    Wu Y; Lee SH; Williamson EA; Reinert BL; Cho JH; Xia F; Jaiswal AS; Srinivasan G; Patel B; Brantley A; Zhou D; Shao L; Pathak R; Hauer-Jensen M; Singh S; Kong K; Wu X; Kim HS; Beissbarth T; Gaedcke J; Burma S; Nickoloff JA; Hromas RA
    PLoS Genet; 2015 Dec; 11(12):e1005675. PubMed ID: 26684013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.