BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 35414769)

  • 1. Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway.
    Zhang Z; Yao T; Zhao N; Liu H; Cheng H; Gonzalez FJ; Wang H; Wang G; Qu A; Wang Y
    Int J Biol Sci; 2022; 18(6):2317-2328. PubMed ID: 35414769
    [No Abstract]   [Full Text] [Related]  

  • 2. Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.
    Patterson AD; Shah YM; Matsubara T; Krausz KW; Gonzalez FJ
    Hepatology; 2012 Jul; 56(1):281-90. PubMed ID: 22318764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FGF21 mediates the protective effect of fenofibrate against acetaminophen -induced hepatotoxicity via activating autophagy in mice.
    Zhang Y; Pan Y; Xiong R; Zheng J; Li Q; Zhang S; Li X; Pan X; Yang S
    Biochem Biophys Res Commun; 2018 Sep; 503(2):474-481. PubMed ID: 29730296
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
    Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity.
    Li D; Du Y; Yuan X; Han X; Dong Z; Chen X; Wu H; Zhang J; Xu L; Han C; Zhang M; Xia Q
    Free Radic Biol Med; 2017 Sep; 110():102-116. PubMed ID: 28583670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Myeloid peroxisome proliferator-activated receptor α deficiency accelerates liver regeneration via IL-6/STAT3 pathway after 2/3 partial hepatectomy in mice.
    Xie G; Song Y; Li N; Zhang Z; Wang X; Liu Y; Jiao S; Wei M; Yu B; Wang Y; Wang H; Qu A
    Hepatobiliary Surg Nutr; 2022 Apr; 11(2):199-211. PubMed ID: 35464270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pectolinarigenin ameliorates acetaminophen-induced acute liver injury via attenuating oxidative stress and inflammatory response in Nrf2 and PPARa dependent manners.
    Li Q; Zhang W; Cheng N; Zhu Y; Li H; Zhang S; Guo W; Ge G
    Phytomedicine; 2023 May; 113():154726. PubMed ID: 36863308
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
    McCarthy TC; Pollak PT; Hanniman EA; Sinal CJ
    J Pharmacol Exp Ther; 2004 Dec; 311(3):864-73. PubMed ID: 15265979
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3.
    Kim JH; Qu A; Reddy JK; Gao B; Gonzalez FJ
    Hepatology; 2014 Feb; 59(2):695-704. PubMed ID: 23939942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport.
    Xie C; Takahashi S; Brocker CN; He S; Chen L; Xie G; Jang K; Gao X; Krausz KW; Qu A; Levi M; Gonzalez FJ
    Biochim Biophys Acta Mol Cell Biol Lipids; 2019 Oct; 1864(10):1396-1411. PubMed ID: 31195146
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.
    Ferreira DW; Goedken MJ; Rommelaere S; Chasson L; Galland F; Naquet P; Manautou JE
    Biochim Biophys Acta; 2016 Apr; 1862(4):662-669. PubMed ID: 26850476
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.
    Chen C; Krausz KW; Shah YM; Idle JR; Gonzalez FJ
    Chem Res Toxicol; 2009 Apr; 22(4):699-707. PubMed ID: 19256530
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice.
    Ye D; Wang Y; Li H; Jia W; Man K; Lo CM; Wang Y; Lam KS; Xu A
    Hepatology; 2014 Sep; 60(3):977-89. PubMed ID: 24590984
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of suppressor of cytokine signaling-3 in T cells exacerbates acetaminophen-induced hepatotoxicity.
    Numata K; Kubo M; Watanabe H; Takagi K; Mizuta H; Okada S; Kunkel SL; Ito T; Matsukawa A
    J Immunol; 2007 Mar; 178(6):3777-85. PubMed ID: 17339476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The TGFβ1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice.
    McMillin M; Grant S; Frampton G; Petrescu AD; Williams E; Jefferson B; DeMorrow S
    Toxicol Sci; 2019 May; 170(2):549-561. PubMed ID: 31132129
    [TBL] [Abstract][Full Text] [Related]  

  • 16. M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.
    Urrunaga NH; Jadeja RN; Rachakonda V; Ahmad D; McLean LP; Cheng K; Shah V; Twaddell WS; Raufman JP; Khurana S
    Free Radic Biol Med; 2015 Jan; 78():66-81. PubMed ID: 25452146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
    Zhu XX; Wang X; Jiao SY; Liu Y; Shi L; Xu Q; Wang JJ; Chen YE; Zhang Q; Song YT; Wei M; Yu BQ; Fielitz J; Gonzalez FJ; Du J; Qu AJ
    Acta Pharmacol Sin; 2023 Nov; 44(11):2184-2200. PubMed ID: 37328648
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatocyte-specific Mas activation enhances lipophagy and fatty acid oxidation to protect against acetaminophen-induced hepatotoxicity in mice.
    Chen S; Lu Z; Jia H; Yang B; Liu C; Yang Y; Zhang S; Wang Z; Yang L; Li S; Li J; Yang C
    J Hepatol; 2023 Mar; 78(3):543-557. PubMed ID: 36368597
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Omega‑3 polyunsaturated fatty acids inhibit IL‑11/STAT3 signaling in hepatocytes during acetaminophen hepatotoxicity.
    Liu Y; Lin J; Chen Y; Li Z; Zhou J; Lu X; Chen Z; Zuo D
    Int J Mol Med; 2021 Oct; 48(4):. PubMed ID: 34414450
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling.
    Liu A; Tanaka N; Sun L; Guo B; Kim JH; Krausz KW; Fang Z; Jiang C; Yang J; Gonzalez FJ
    Chem Biol Interact; 2014 Nov; 223():80-6. PubMed ID: 25265579
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.