These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 35416431)

  • 1. Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition.
    Demarta-Gatsi C; Donini C; Duffy J; Sadler C; Stewart J; Barber JA; Tornesi B
    Birth Defects Res; 2022 Jun; 114(10):487-498. PubMed ID: 35416431
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of
    Dziwornu GA; Seanego D; Fienberg S; Clements M; Ferreira J; Sypu VS; Samanta S; Bhana AD; Korkor CM; Garnie LF; Teixeira N; Wicht KJ; Taylor D; Olckers R; Njoroge M; Gibhard L; Salomane N; Wittlin S; Mahato R; Chakraborty A; Sevilleno N; Coyle R; Lee MCS; Godoy LC; Pasaje CF; Niles JC; Reader J; van der Watt M; Birkholtz LM; Bolscher JM; de Bruijni MHC; Coulson LB; Basarab GS; Ghorpade SR; Chibale K
    J Med Chem; 2024 Jul; 67(13):11401-11420. PubMed ID: 38918002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
    Brunschwig C; Lawrence N; Taylor D; Abay E; Njoroge M; Basarab GS; Le Manach C; Paquet T; Cabrera DG; Nchinda AT; de Kock C; Wiesner L; Denti P; Waterson D; Blasco B; Leroy D; Witty MJ; Donini C; Duffy J; Wittlin S; White KL; Charman SA; Jiménez-Díaz MB; Angulo-Barturen I; Herreros E; Gamo FJ; Rochford R; Mancama D; Coetzer TL; van der Watt ME; Reader J; Birkholtz LM; Marsh KC; Solapure SM; Burke JE; McPhail JA; Vanaerschot M; Fidock DA; Fish PV; Siegl P; Smith DA; Wirjanata G; Noviyanti R; Price RN; Marfurt J; Silue KD; Street LJ; Chibale K
    Antimicrob Agents Chemother; 2018 Sep; 62(9):. PubMed ID: 29941635
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of 6'-chloro-N-methyl-5'-(phenylsulfonamido)-[3,3'-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium.
    Liang X; Jiang Z; Huang Z; Li F; Chen C; Hu C; Wang W; Hu Z; Liu Q; Wang B; Wang L; Qi Z; Liu J; Jiang L; Liu Q
    Eur J Med Chem; 2020 Feb; 188():112012. PubMed ID: 31911293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of
    Cheuka PM; Centani L; Arendse LB; Fienberg S; Wambua L; Renga SS; Dziwornu GA; Kumar M; Lawrence N; Taylor D; Wittlin S; Coertzen D; Reader J; van der Watt M; Birkholtz LM; Chibale K
    ACS Infect Dis; 2021 Jan; 7(1):34-46. PubMed ID: 33319990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antimalarial efficacy of MMV390048, an inhibitor of
    Paquet T; Le Manach C; Cabrera DG; Younis Y; Henrich PP; Abraham TS; Lee MCS; Basak R; Ghidelli-Disse S; Lafuente-Monasterio MJ; Bantscheff M; Ruecker A; Blagborough AM; Zakutansky SE; Zeeman AM; White KL; Shackleford DM; Mannila J; Morizzi J; Scheurer C; Angulo-Barturen I; Martínez MS; Ferrer S; Sanz LM; Gamo FJ; Reader J; Botha M; Dechering KJ; Sauerwein RW; Tungtaeng A; Vanachayangkul P; Lim CS; Burrows J; Witty MJ; Marsh KC; Bodenreider C; Rochford R; Solapure SM; Jiménez-Díaz MB; Wittlin S; Charman SA; Donini C; Campo B; Birkholtz LM; Hanson KK; Drewes G; Kocken CHM; Delves MJ; Leroy D; Fidock DA; Waterson D; Street LJ; Chibale K
    Sci Transl Med; 2017 Apr; 9(387):. PubMed ID: 28446690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Research progress of phosphatidylinositol 4-kinase and its inhibitors in inflammatory diseases.
    Li YP; Mikrani R; Hu YF; Faran Ashraf Baig MM; Abbas M; Akhtar F; Xu M
    Eur J Pharmacol; 2021 Sep; 907():174300. PubMed ID: 34217706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Phase 1, Placebo-controlled, Randomized, Single Ascending Dose Study and a Volunteer Infection Study to Characterize the Safety, Pharmacokinetics, and Antimalarial Activity of the Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048.
    McCarthy JS; Donini C; Chalon S; Woodford J; Marquart L; Collins KA; Rozenberg FD; Fidock DA; Cherkaoui-Rbati MH; Gobeau N; Möhrle JJ
    Clin Infect Dis; 2020 Dec; 71(10):e657-e664. PubMed ID: 32239164
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Basis for Inhibitor Potency and Selectivity of
    Fienberg S; Eyermann CJ; Arendse LB; Basarab GS; McPhail JA; Burke JE; Chibale K
    ACS Infect Dis; 2020 Nov; 6(11):3048-3063. PubMed ID: 32966036
    [No Abstract]   [Full Text] [Related]  

  • 10. An assessment of the reliability of 52 enhanced preliminary embryofetal development studies to detect developmental toxicity.
    Barrow P
    Birth Defects Res; 2023 Jan; 115(2):218-223. PubMed ID: 36331145
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of rat and rabbit embryofetal development studies with pharmaceuticals: the added value of a second species.
    Roos P; Anggasta C; Piersma AH; van Meer PJK; Theunissen PT
    Crit Rev Toxicol; 2024 Oct; 54(9):619-633. PubMed ID: 39093553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of PI3-kinase and PI4-kinase in actin polymerization during bovine sperm capacitation.
    Etkovitz N; Rubinstein S; Daniel L; Breitbart H
    Biol Reprod; 2007 Aug; 77(2):263-73. PubMed ID: 17494916
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plasmodial Kinase Inhibitors: License to Cure?
    Cabrera DG; Horatscheck A; Wilson CR; Basarab G; Eyermann CJ; Chibale K
    J Med Chem; 2018 Sep; 61(18):8061-8077. PubMed ID: 29771541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of phosphatidylinositol 4-kinase results in a significant reduced respiratory burst in formyl-methionyl-leucyl-phenylalanine-stimulated human neutrophils.
    Yue J; Liu J; Shen X
    J Biol Chem; 2001 Dec; 276(52):49093-9. PubMed ID: 11592957
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Developing kinase inhibitors for malaria: an opportunity or liability?
    Mogwera KSP; Chibale K; Arendse LB
    Trends Parasitol; 2023 Sep; 39(9):720-731. PubMed ID: 37385921
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pathophysiological concentrations of amyloid beta proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activity.
    Wu B; Kitagawa K; Zhang NY; Liu B; Inagaki C
    J Neurochem; 2004 Dec; 91(5):1164-70. PubMed ID: 15569259
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors.
    Sorensen SD; Linseman DA; McEwen EL; Heacock AM; Fisher SK
    Mol Pharmacol; 1998 May; 53(5):827-36. PubMed ID: 9584208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells.
    Zhao X; Várnai P; Tuymetova G; Balla A; Tóth ZE; Oker-Blom C; Roder J; Jeromin A; Balla T
    J Biol Chem; 2001 Oct; 276(43):40183-9. PubMed ID: 11526106
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Phosphatidylinositol 4-Kinase IIIα for Radiosensitization: A Potential Model of Drug Repositioning Using an Anti-Hepatitis C Viral Agent.
    Kwon J; Kim DH; Park JM; Park YH; Hwang YH; Wu HG; Shin KH; Kim IA
    Int J Radiat Oncol Biol Phys; 2016 Nov; 96(4):867-876. PubMed ID: 27788957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fertility and Embryo-Fetal Development Assessment in Rats and Rabbits with Evacetrapib: A Cholesteryl Ester Transfer Protein Inhibitor.
    Breslin WJ; Hilbish KG; Cannady EA; Edwards TL
    Birth Defects Res; 2017 Apr; 109(7):513-527. PubMed ID: 28398618
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.