285 related articles for article (PubMed ID: 35418677)
1. Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Xiao P; Guo S; Wen X; He QT; Lin H; Huang SM; Gou L; Zhang C; Yang Z; Zhong YN; Yang CC; Li Y; Gong Z; Tao XN; Yang ZS; Lu Y; Li SL; He JY; Wang C; Zhang L; Kong L; Sun JP; Yu X
Nature; 2022 Apr; 604(7907):771-778. PubMed ID: 35418677
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the tethered peptide activation of adhesion GPCRs.
Ping YQ; Xiao P; Yang F; Zhao RJ; Guo SC; Yan X; Wu X; Zhang C; Lu Y; Zhao F; Zhou F; Xi YT; Yin W; Liu FZ; He DF; Zhang DL; Zhu ZL; Jiang Y; Du L; Feng SQ; Schöneberg T; Liebscher I; Xu HE; Sun JP
Nature; 2022 Apr; 604(7907):763-770. PubMed ID: 35418678
[TBL] [Abstract][Full Text] [Related]
3. Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology.
Sun Y; Zhang D; Ma ML; Lin H; Song Y; Wang J; Ma C; Yu K; An W; Guo S; He D; Yang Z; Xiao P; Hou G; Yu X; Sun JP
J Biol Chem; 2021; 296():100174. PubMed ID: 33303626
[TBL] [Abstract][Full Text] [Related]
4. Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2.
Gad AA; Azimzadeh P; Balenga N
Sci Rep; 2021 Jul; 11(1):14060. PubMed ID: 34234254
[TBL] [Abstract][Full Text] [Related]
5. Activation of Adhesion G Protein-coupled Receptors: AGONIST SPECIFICITY OF STACHEL SEQUENCE-DERIVED PEPTIDES.
Demberg LM; Winkler J; Wilde C; Simon KU; Schön J; Rothemund S; Schöneberg T; Prömel S; Liebscher I
J Biol Chem; 2017 Mar; 292(11):4383-4394. PubMed ID: 28154189
[TBL] [Abstract][Full Text] [Related]
6. 7TM Domain Structure of Adhesion GPCRs.
de Graaf C; Nijmeijer S; Wolf S; Ernst OP
Handb Exp Pharmacol; 2016; 234():43-66. PubMed ID: 27832483
[TBL] [Abstract][Full Text] [Related]
7. 7TM domain structures of adhesion GPCRs: what's new and what's missing?
Seufert F; Chung YK; Hildebrand PW; Langenhan T
Trends Biochem Sci; 2023 Aug; 48(8):726-739. PubMed ID: 37349240
[TBL] [Abstract][Full Text] [Related]
8. Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2.
Demberg LM; Rothemund S; Schöneberg T; Liebscher I
Biochem Biophys Res Commun; 2015 Aug; 464(3):743-7. PubMed ID: 26188515
[TBL] [Abstract][Full Text] [Related]
9. Mechanistic Insights into Peptide Binding and Deactivation of an Adhesion G Protein-Coupled Receptor.
Adediwura VA; Miao Y
Molecules; 2023 Dec; 29(1):. PubMed ID: 38202747
[TBL] [Abstract][Full Text] [Related]
10. The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist.
Wilde C; Fischer L; Lede V; Kirchberger J; Rothemund S; Schöneberg T; Liebscher I
FASEB J; 2016 Feb; 30(2):666-73. PubMed ID: 26499266
[TBL] [Abstract][Full Text] [Related]
11. Conformational transitions and activation of the adhesion receptor CD97.
Mao C; Zhao RJ; Dong YJ; Gao M; Chen LN; Zhang C; Xiao P; Guo J; Qin J; Shen DD; Ji SY; Zang SK; Zhang H; Wang WW; Shen Q; Sun JP; Zhang Y
Mol Cell; 2024 Feb; 84(3):570-583.e7. PubMed ID: 38215752
[TBL] [Abstract][Full Text] [Related]
12. Structural clarity is brought to adhesion G protein-coupled receptor tethered agonism.
Gupta C; Bernadyn TF; Tall GG
Basic Clin Pharmacol Toxicol; 2023 Oct; 133(4):295-300. PubMed ID: 36585032
[TBL] [Abstract][Full Text] [Related]
13. Structures of the ADGRG2-G
Lin H; Xiao P; Bu RQ; Guo S; Yang Z; Yuan D; Zhu ZL; Zhang CX; He QT; Zhang C; Ping YQ; Zhao RJ; Ma CS; Liu CH; Zhang XN; Jiang D; Huang S; Xi YT; Zhang DL; Xue CY; Yang BS; Li JY; Lin HC; Zeng XH; Zhao H; Xu WM; Yi F; Liu Z; Sun JP; Yu X
Nat Chem Biol; 2022 Nov; 18(11):1196-1203. PubMed ID: 35982227
[TBL] [Abstract][Full Text] [Related]
14. Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs.
Liebscher I; Schöneberg T
Handb Exp Pharmacol; 2016; 234():111-125. PubMed ID: 27832486
[TBL] [Abstract][Full Text] [Related]
15. Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain.
Beliu G; Altrichter S; Guixà-González R; Hemberger M; Brauer I; Dahse AK; Scholz N; Wieduwild R; Kuhlemann A; Batebi H; Seufert F; Pérez-Hernández G; Hildebrand PW; Sauer M; Langenhan T
Mol Cell; 2021 Mar; 81(5):905-921.e5. PubMed ID: 33497605
[TBL] [Abstract][Full Text] [Related]
16. Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information.
Kleinau G; Ali AH; Wiechert F; Szczepek M; Schmidt A; Spahn CMT; Liebscher I; Schöneberg T; Scheerer P
Pharmacol Res; 2023 Nov; 197():106971. PubMed ID: 38032292
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of adhesion G protein-coupled receptor activation.
Vizurraga A; Adhikari R; Yeung J; Yu M; Tall GG
J Biol Chem; 2020 Oct; 295(41):14065-14083. PubMed ID: 32763969
[TBL] [Abstract][Full Text] [Related]
18. A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133.
Liebscher I; Schön J; Petersen SC; Fischer L; Auerbach N; Demberg LM; Mogha A; Cöster M; Simon KU; Rothemund S; Monk KR; Schöneberg T
Cell Rep; 2014 Dec; 9(6):2018-26. PubMed ID: 25533341
[TBL] [Abstract][Full Text] [Related]
19. GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist.
Zhu B; Luo R; Jin P; Li T; Oak HC; Giera S; Monk KR; Lak P; Shoichet BK; Piao X
J Biol Chem; 2019 Dec; 294(50):19246-19254. PubMed ID: 31628191
[TBL] [Abstract][Full Text] [Related]
20. Structural basis of CD97 activation and G-protein coupling.
Wang N; Qian Y; Xia R; Zhu X; Xiong Y; Zhang A; Guo C; He Y
Cell Chem Biol; 2023 Nov; 30(11):1343-1353.e5. PubMed ID: 37673067
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
