These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase. Adedeji AO; Singh K; Calcaterra NE; DeDiego ML; Enjuanes L; Weiss S; Sarafianos SG Antimicrob Agents Chemother; 2012 Sep; 56(9):4718-28. PubMed ID: 22733076 [TBL] [Abstract][Full Text] [Related]
3. Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach. Romeo I; Ambrosio FA; Costa G; Corona A; Alkhatib M; Salpini R; Lemme S; Vergni D; Svicher V; Santoro MM; Tramontano E; Ceccherini-Silberstein F; Artese A; Alcaro S Molecules; 2022 Nov; 27(21):. PubMed ID: 36364347 [TBL] [Abstract][Full Text] [Related]
4. In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity. Mohammad TSH; Gupta Y; Reidl CT; Nicolaescu V; Gula H; Durvasula R; Kempaiah P; Becker DP Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982188 [TBL] [Abstract][Full Text] [Related]
5. The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity. Yue K; Yao B; Shi Y; Yang Y; Qian Z; Ci Y; Shi L Biochem Biophys Res Commun; 2022 Apr; 601():129-136. PubMed ID: 35245742 [TBL] [Abstract][Full Text] [Related]
6. Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13. Yu MS; Lee J; Lee JM; Kim Y; Chin YW; Jee JG; Keum YS; Jeong YJ Bioorg Med Chem Lett; 2012 Jun; 22(12):4049-54. PubMed ID: 22578462 [TBL] [Abstract][Full Text] [Related]
8. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. Yazdi AK; Pakarian P; Perveen S; Hajian T; Santhakumar V; Bolotokova A; Li F; Vedadi M ACS Infect Dis; 2022 Aug; 8(8):1533-1542. PubMed ID: 35822715 [TBL] [Abstract][Full Text] [Related]
9. Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions. Sommers JA; Loftus LN; Jones MP; Lee RA; Haren CE; Dumm AJ; Brosh RM J Biol Chem; 2023 Mar; 299(3):102980. PubMed ID: 36739951 [TBL] [Abstract][Full Text] [Related]
10. Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. Ivanov KA; Thiel V; Dobbe JC; van der Meer Y; Snijder EJ; Ziebuhr J J Virol; 2004 Jun; 78(11):5619-32. PubMed ID: 15140959 [TBL] [Abstract][Full Text] [Related]
11. SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts. Shu T; Huang M; Wu D; Ren Y; Zhang X; Han Y; Mu J; Wang R; Qiu Y; Zhang DY; Zhou X Virol Sin; 2020 Jun; 35(3):321-329. PubMed ID: 32500504 [TBL] [Abstract][Full Text] [Related]
12. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase. Zeng J; Weissmann F; Bertolin AP; Posse V; Canal B; Ulferts R; Wu M; Harvey R; Hussain S; Milligan JC; Roustan C; Borg A; McCoy L; Drury LS; Kjaer S; McCauley J; Howell M; Beale R; Diffley JFX Biochem J; 2021 Jul; 478(13):2405-2423. PubMed ID: 34198322 [TBL] [Abstract][Full Text] [Related]
14. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. Mickolajczyk KJ; Shelton PMM; Grasso M; Cao X; Warrington SR; Aher A; Liu S; Kapoor TM bioRxiv; 2020 Jul; ():. PubMed ID: 32766580 [TBL] [Abstract][Full Text] [Related]
15. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. Mickolajczyk KJ; Shelton PMM; Grasso M; Cao X; Warrington SE; Aher A; Liu S; Kapoor TM Biophys J; 2021 Mar; 120(6):1020-1030. PubMed ID: 33340543 [TBL] [Abstract][Full Text] [Related]
16. Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase. Weber R; McCullagh M J Phys Chem B; 2021 Aug; 125(31):8787-8796. PubMed ID: 34328740 [TBL] [Abstract][Full Text] [Related]
17. SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1. Fung SY; Siu KL; Lin H; Chan CP; Yeung ML; Jin DY Cell Biosci; 2022 Mar; 12(1):36. PubMed ID: 35317858 [TBL] [Abstract][Full Text] [Related]
18. Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Newman JA; Douangamath A; Yadzani S; Yosaatmadja Y; Aimon A; Brandão-Neto J; Dunnett L; Gorrie-Stone T; Skyner R; Fearon D; Schapira M; von Delft F; Gileadi O Nat Commun; 2021 Aug; 12(1):4848. PubMed ID: 34381037 [TBL] [Abstract][Full Text] [Related]
19. Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase. Mirza MU; Froeyen M J Pharm Anal; 2020 Aug; 10(4):320-328. PubMed ID: 32346490 [TBL] [Abstract][Full Text] [Related]
20. SARS-CoV-2 Nucleocapsid Protein Has DNA-Melting and Strand-Annealing Activities With Different Properties From SARS-CoV-2 Nsp13. Zhang B; Xie Y; Lan Z; Li D; Tian J; Zhang Q; Tian H; Yang J; Zhou X; Qiu S; Lu K; Liu Y Front Microbiol; 2022; 13():851202. PubMed ID: 35935242 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]