128 related articles for article (PubMed ID: 35434831)
1. U2AF1 mutation connects DNA damage to the alternative splicing of RAD51 in lung adenocarcinomas.
Chen C; Zhou P; Zhang Z; Liu Y
Clin Exp Pharmacol Physiol; 2022 Jul; 49(7):740-747. PubMed ID: 35434831
[TBL] [Abstract][Full Text] [Related]
2. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.
Esfahani MS; Lee LJ; Jeon YJ; Flynn RA; Stehr H; Hui AB; Ishisoko N; Kildebeck E; Newman AM; Bratman SV; Porteus MH; Chang HY; Alizadeh AA; Diehn M
Nat Commun; 2019 Dec; 10(1):5712. PubMed ID: 31836708
[TBL] [Abstract][Full Text] [Related]
3. Integrative Profiling of Alternative Splicing Induced by
Kim S; Park C; Jun Y; Lee S; Jung Y; Kim J
Mol Cells; 2018 Aug; 41(8):733-741. PubMed ID: 29991672
[TBL] [Abstract][Full Text] [Related]
4. Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.
Fei DL; Motowski H; Chatrikhi R; Prasad S; Yu J; Gao S; Kielkopf CL; Bradley RK; Varmus H
PLoS Genet; 2016 Oct; 12(10):e1006384. PubMed ID: 27776121
[TBL] [Abstract][Full Text] [Related]
5. Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice.
Kim SP; Srivatsan SN; Chavez M; Shirai CL; White BS; Ahmed T; Alberti MO; Shao J; Nunley R; White LS; Bednarski J; Pehrson JR; Walter MJ
Cell Rep; 2021 Aug; 36(9):109626. PubMed ID: 34469727
[TBL] [Abstract][Full Text] [Related]
6. Full-length transcript alterations in human bronchial epithelial cells with
Soulette CM; Hrabeta-Robinson E; Arevalo C; Felton C; Tang AD; Marin MG; Brooks AN
Life Sci Alliance; 2023 Oct; 6(10):. PubMed ID: 37487637
[No Abstract] [Full Text] [Related]
7. Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene
Fei DL; Zhen T; Durham B; Ferrarone J; Zhang T; Garrett L; Yoshimi A; Abdel-Wahab O; Bradley RK; Liu P; Varmus H
Proc Natl Acad Sci U S A; 2018 Oct; 115(44):E10437-E10446. PubMed ID: 30322915
[TBL] [Abstract][Full Text] [Related]
8. Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes.
Nguyen HD; Leong WY; Li W; Reddy PNG; Sullivan JD; Walter MJ; Zou L; Graubert TA
Cancer Res; 2018 Sep; 78(18):5363-5374. PubMed ID: 30054334
[TBL] [Abstract][Full Text] [Related]
9. A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.
Brooks AN; Choi PS; de Waal L; Sharifnia T; Imielinski M; Saksena G; Pedamallu CS; Sivachenko A; Rosenberg M; Chmielecki J; Lawrence MS; DeLuca DS; Getz G; Meyerson M
PLoS One; 2014; 9(1):e87361. PubMed ID: 24498085
[TBL] [Abstract][Full Text] [Related]
10. U2AF1 mutation promotes tumorigenicity through facilitating autophagy flux mediated by FOXO3a activation in myelodysplastic syndromes.
Zhu Y; Song D; Guo J; Jin J; Tao Y; Zhang Z; Xu F; He Q; Li X; Chang C; Wu L
Cell Death Dis; 2021 Jun; 12(7):655. PubMed ID: 34183647
[TBL] [Abstract][Full Text] [Related]
11. Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation.
Akef A; McGraw K; Cappell SD; Larson DR
PLoS Biol; 2020 Nov; 18(11):e3000920. PubMed ID: 33137094
[TBL] [Abstract][Full Text] [Related]
12. A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.
Warnasooriya C; Feeney CF; Laird KM; Ermolenko DN; Kielkopf CL
Nucleic Acids Res; 2020 Jun; 48(10):5695-5709. PubMed ID: 32343311
[TBL] [Abstract][Full Text] [Related]
13. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Shirai CL; White BS; Tripathi M; Tapia R; Ley JN; Ndonwi M; Kim S; Shao J; Carver A; Saez B; Fulton RS; Fronick C; O'Laughlin M; Lagisetti C; Webb TR; Graubert TA; Walter MJ
Nat Commun; 2017 Jan; 8():14060. PubMed ID: 28067246
[TBL] [Abstract][Full Text] [Related]
14. U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.
Okeyo-Owuor T; White BS; Chatrikhi R; Mohan DR; Kim S; Griffith M; Ding L; Ketkar-Kulkarni S; Hundal J; Laird KM; Kielkopf CL; Ley TJ; Walter MJ; Graubert TA
Leukemia; 2015 Apr; 29(4):909-17. PubMed ID: 25311244
[TBL] [Abstract][Full Text] [Related]
15. The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation.
Palangat M; Anastasakis DG; Fei DL; Lindblad KE; Bradley R; Hourigan CS; Hafner M; Larson DR
Genes Dev; 2019 May; 33(9-10):482-497. PubMed ID: 30842218
[TBL] [Abstract][Full Text] [Related]
16. U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice.
Wadugu BA; Nonavinkere Srivatsan S; Heard A; Alberti MO; Ndonwi M; Liu J; Grieb S; Bradley J; Shao J; Ahmed T; Shirai CL; Khanna A; Fei DL; Miller CA; Graubert TA; Walter MJ
J Clin Invest; 2021 Nov; 131(21):. PubMed ID: 34546980
[TBL] [Abstract][Full Text] [Related]
17. Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Biancon G; Joshi P; Zimmer JT; Hunck T; Gao Y; Lessard MD; Courchaine E; Barentine AES; Machyna M; Botti V; Qin A; Gbyli R; Patel A; Song Y; Kiefer L; Viero G; Neuenkirchen N; Lin H; Bewersdorf J; Simon MD; Neugebauer KM; Tebaldi T; Halene S
Mol Cell; 2022 Mar; 82(6):1107-1122.e7. PubMed ID: 35303483
[TBL] [Abstract][Full Text] [Related]
18. High expression of RAD51 promotes DNA damage repair and survival in KRAS-mutant lung cancer cells.
Hu J; Zhang Z; Zhao L; Li L; Zuo W; Han L
BMB Rep; 2019 Feb; 52(2):151-156. PubMed ID: 30638176
[TBL] [Abstract][Full Text] [Related]
19. Mutant U2AF1-Induced Mis-Splicing of mRNA Translation Genes Confers Resistance to Chemotherapy in Acute Myeloid Leukemia.
Jin P; Wang X; Jin Q; Zhang Y; Shen J; Jiang G; Zhu H; Zhao M; Wang D; Li Z; Zhou Y; Li W; Zhang W; Liu Y; Wang S; Jin W; Cao Y; Sheng G; Dong F; Wu S; Li X; Jin Z; He M; Liu X; Chen L; Zhang Y; Wang K; Li J
Cancer Res; 2024 May; 84(10):1583-1596. PubMed ID: 38417135
[TBL] [Abstract][Full Text] [Related]
20. Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes.
Martínez-Valiente C; Garcia-Ruiz C; Rosón B; Liquori A; González-Romero E; Fernández-González R; Gómez-Redondo I; Cervera J; Gutiérrez-Adán A; Sanjuan-Pla A
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34203454
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
