104 related articles for article (PubMed ID: 35442672)
1. Discovery of First-in-Class TAK1-MKK3 Protein-Protein Interaction (PPI) Inhibitor
Tang ML; Li H; Ning JF; Shen X; Sun X
J Med Chem; 2022 May; 65(9):6690-6709. PubMed ID: 35442672
[TBL] [Abstract][Full Text] [Related]
2. TGF-beta-activated kinase 1 and TAK1-binding protein 1 cooperate to mediate TGF-beta1-induced MKK3-p38 MAPK activation and stimulation of type I collagen.
Kim SI; Kwak JH; Zachariah M; He Y; Wang L; Choi ME
Am J Physiol Renal Physiol; 2007 May; 292(5):F1471-8. PubMed ID: 17299140
[TBL] [Abstract][Full Text] [Related]
3. APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.
Xin X; Zhou L; Reyes CM; Liu F; Dong LQ
Am J Physiol Endocrinol Metab; 2011 Jan; 300(1):E103-10. PubMed ID: 20978232
[TBL] [Abstract][Full Text] [Related]
4. Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis.
Inoue T; Boyle DL; Corr M; Hammaker D; Davis RJ; Flavell RA; Firestein GS
Proc Natl Acad Sci U S A; 2006 Apr; 103(14):5484-9. PubMed ID: 16567640
[TBL] [Abstract][Full Text] [Related]
5. Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.
Edlund S; Bu S; Schuster N; Aspenström P; Heuchel R; Heldin NE; ten Dijke P; Heldin CH; Landström M
Mol Biol Cell; 2003 Feb; 14(2):529-44. PubMed ID: 12589052
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.
Qi Z; Shen L; Zhou H; Jiang Y; Lan L; Luo L; Yin Z
Cell Signal; 2014 Jul; 26(7):1616-25. PubMed ID: 24686082
[TBL] [Abstract][Full Text] [Related]
7. Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL.
Huang H; Ryu J; Ha J; Chang EJ; Kim HJ; Kim HM; Kitamura T; Lee ZH; Kim HH
Cell Death Differ; 2006 Nov; 13(11):1879-91. PubMed ID: 16498455
[TBL] [Abstract][Full Text] [Related]
8. TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
Nishimura M; Shin MS; Singhirunnusorn P; Suzuki S; Kawanishi M; Koizumi K; Saiki I; Sakurai H
Mol Cell Biol; 2009 Oct; 29(20):5529-39. PubMed ID: 19687304
[TBL] [Abstract][Full Text] [Related]
9. MKK3/6-p38 MAPK signaling is required for IL-1beta and TNF-alpha-induced RANKL expression in bone marrow stromal cells.
Rossa C; Ehmann K; Liu M; Patil C; Kirkwood KL
J Interferon Cytokine Res; 2006 Oct; 26(10):719-29. PubMed ID: 17032166
[TBL] [Abstract][Full Text] [Related]
10. Fragment-based drug discovery of potent and selective MKK3/6 inhibitors.
Adams M; Kobayashi T; Lawson JD; Saitoh M; Shimokawa K; Bigi SV; Hixon MS; Smith CR; Tatamiya T; Goto M; Russo J; Grimshaw CE; Swann S
Bioorg Med Chem Lett; 2016 Feb; 26(3):1086-1089. PubMed ID: 26704264
[TBL] [Abstract][Full Text] [Related]
11. Cross interference with TNF-alpha-induced TAK1 activation via EGFR-mediated p38 phosphorylation of TAK1-binding protein 1.
Shin MS; Shinghirunnusorn P; Sugishima Y; Nishimura M; Suzuki S; Koizumi K; Saiki I; Sakurai H
Biochim Biophys Acta; 2009 Jul; 1793(7):1156-64. PubMed ID: 19393267
[TBL] [Abstract][Full Text] [Related]
12. Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-α actions in human adipose tissue-derived stromal cells.
Lee SY; Lee JH; Shin KK; Kim DS; Kim YS; Bae YC; Jung JS
Stem Cells Dev; 2015 Apr; 24(7):836-45. PubMed ID: 25350220
[TBL] [Abstract][Full Text] [Related]
13. Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.
Yang X; Fan D; Troha AH; Ahn HM; Qian K; Liang B; Du Y; Fu H; Ivanov AA
Bioorg Med Chem; 2021 Sep; 45():116324. PubMed ID: 34333394
[TBL] [Abstract][Full Text] [Related]
14. Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia.
Tanno M; Bassi R; Gorog DA; Saurin AT; Jiang J; Heads RJ; Martin JL; Davis RJ; Flavell RA; Marber MS
Circ Res; 2003 Aug; 93(3):254-61. PubMed ID: 12829618
[TBL] [Abstract][Full Text] [Related]
15. Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
Totzke J; Gurbani D; Raphemot R; Hughes PF; Bodoor K; Carlson DA; Loiselle DR; Bera AK; Eibschutz LS; Perkins MM; Eubanks AL; Campbell PL; Fox DA; Westover KD; Haystead TAJ; Derbyshire ER
Cell Chem Biol; 2017 Aug; 24(8):1029-1039.e7. PubMed ID: 28820959
[TBL] [Abstract][Full Text] [Related]
16. MiR-92b-3p ameliorates inflammation and autophagy by targeting TRAF3 and suppressing MKK3-p38 pathway in caerulein-induced AR42J cells.
Sun H; Tian J; Li J
Int Immunopharmacol; 2020 Nov; 88():106691. PubMed ID: 32822908
[TBL] [Abstract][Full Text] [Related]
17. The aryl hydrocarbon receptor is a novel negative regulator of interleukin-17-mediated signaling and inflammation in vitro.
Li H; Hong W; Jin X; Li G; Zhou G; Fan L
FEBS Lett; 2019 May; 593(9):952-961. PubMed ID: 30953345
[TBL] [Abstract][Full Text] [Related]
18. The in vitro and in vivo anti-inflammatory effect of osthole, the major natural coumarin from Cnidium monnieri (L.) Cuss, via the blocking of the activation of the NF-κB and MAPK/p38 pathways.
Fan H; Gao Z; Ji K; Li X; Wu J; Liu Y; Wang X; Liang H; Liu Y; Li X; Liu P; Chen D; Zhao F
Phytomedicine; 2019 May; 58():152864. PubMed ID: 30878874
[TBL] [Abstract][Full Text] [Related]
19. OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc.
Ivanov AA; Gonzalez-Pecchi V; Khuri LF; Niu Q; Wang Y; Xu Y; Bai Y; Mo X; Prochownik EV; Johns MA; Du Y; Khuri FR; Fu H
Oncogene; 2017 Oct; 36(42):5852-5860. PubMed ID: 28628118
[TBL] [Abstract][Full Text] [Related]
20. RACK1 antagonizes TNF-α-induced cell death by promoting p38 activation.
Wang Q; Zhou S; Wang JY; Cao J; Zhang X; Wang J; Han K; Cheng Q; Qiu G; Zhao Y; Li X; Qiao C; Li Y; Hou C; Zhang J
Sci Rep; 2015 Sep; 5():14298. PubMed ID: 26381936
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
