128 related articles for article (PubMed ID: 35445405)
1. The porcupine inhibitor WNT974 provokes ectodermal lineage differentiation of human embryonic stem cells.
Kalantary-Charvadeh A; Hosseini V; Mehdizadeh A; Nazari Soltan Ahmad S; Rahbarghazi R; Nozad Charoudeh H; Nouri M; Darabi M
Cell Biochem Funct; 2022 Jun; 40(4):359-368. PubMed ID: 35445405
[TBL] [Abstract][Full Text] [Related]
2. A small molecule modulating monounsaturated fatty acids and Wnt signaling confers maintenance to induced pluripotent stem cells against endodermal differentiation.
Hosseini V; Kalantary-Charvadeh A; Hajikarami M; Fayyazpour P; Rahbarghazi R; Totonchi M; Darabi M
Stem Cell Res Ther; 2021 Oct; 12(1):550. PubMed ID: 34674740
[TBL] [Abstract][Full Text] [Related]
3. Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
Li J; Wu G; Xu Y; Li J; Ruan N; Chen Y; Zhang Q; Xia Q
Biomed Res Int; 2020; 2020():2527643. PubMed ID: 32104684
[TBL] [Abstract][Full Text] [Related]
4. An
Asciolla JJ; Miele MM; Hendrickson RC; Resh MD
J Biol Chem; 2017 Aug; 292(33):13507-13513. PubMed ID: 28655768
[TBL] [Abstract][Full Text] [Related]
5. Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Liu Y; Qi X; Donnelly L; Elghobashi-Meinhardt N; Long T; Zhou RW; Sun Y; Wang B; Li X
Nature; 2022 Jul; 607(7920):816-822. PubMed ID: 35831507
[TBL] [Abstract][Full Text] [Related]
6. Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN).
Tuladhar R; Yarravarapu N; Ma Y; Zhang C; Herbert J; Kim J; Chen C; Lum L
J Biol Chem; 2019 Apr; 294(16):6273-6282. PubMed ID: 30737280
[TBL] [Abstract][Full Text] [Related]
7. Modulating Wnt signaling at the root: Porcupine and Wnt acylation.
Torres VI; Godoy JA; Inestrosa NC
Pharmacol Ther; 2019 Jun; 198():34-45. PubMed ID: 30790642
[TBL] [Abstract][Full Text] [Related]
8. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
Rao DM; Shackleford MT; Bordeaux EK; Sottnik JL; Ferguson RL; Yamamoto TM; Wellberg EA; Bitler BG; Sikora MJ
J Biol Chem; 2019 Dec; 294(52):19950-19966. PubMed ID: 31740580
[TBL] [Abstract][Full Text] [Related]
9. Identification of key residues and regions important for porcupine-mediated Wnt acylation.
Rios-Esteves J; Haugen B; Resh MD
J Biol Chem; 2014 Jun; 289(24):17009-19. PubMed ID: 24798332
[TBL] [Abstract][Full Text] [Related]
10.
Lee CJ; Rana MS; Bae C; Li Y; Banerjee A
J Biol Chem; 2019 Jan; 294(1):231-245. PubMed ID: 30420431
[TBL] [Abstract][Full Text] [Related]
11. Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist.
Moon J; Zhou H; Zhang LS; Tan W; Liu Y; Zhang S; Morlock LK; Bao X; Palecek SP; Feng JQ; Williams NS; Amatruda JF; Olson EN; Bassel-Duby R; Lum L
Proc Natl Acad Sci U S A; 2017 Feb; 114(7):1649-1654. PubMed ID: 28143939
[TBL] [Abstract][Full Text] [Related]
12. Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI.
Agarwal P; Zhang B; Ho Y; Cook A; Li L; Mikhail FM; Wang Y; McLaughlin ME; Bhatia R
Blood; 2017 Feb; 129(8):1008-1020. PubMed ID: 28011678
[TBL] [Abstract][Full Text] [Related]
13. Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells.
Xu Z; Robitaille AM; Berndt JD; Davidson KC; Fischer KA; Mathieu J; Potter JC; Ruohola-Baker H; Moon RT
Proc Natl Acad Sci U S A; 2016 Oct; 113(42):E6382-E6390. PubMed ID: 27698112
[TBL] [Abstract][Full Text] [Related]
14. Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine.
Cabrae R; Dubuquoy C; Caüzac M; Morzyglod L; Guilmeau S; Noblet B; Fève B; Postic C; Burnol AF; Moldes M
Sci Rep; 2020 Mar; 10(1):5186. PubMed ID: 32198362
[TBL] [Abstract][Full Text] [Related]
15. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Liu J; Pan S; Hsieh MH; Ng N; Sun F; Wang T; Kasibhatla S; Schuller AG; Li AG; Cheng D; Li J; Tompkins C; Pferdekamper A; Steffy A; Cheng J; Kowal C; Phung V; Guo G; Wang Y; Graham MP; Flynn S; Brenner JC; Li C; Villarroel MC; Schultz PG; Wu X; McNamara P; Sellers WR; Petruzzelli L; Boral AL; Seidel HM; McLaughlin ME; Che J; Carey TE; Vanasse G; Harris JL
Proc Natl Acad Sci U S A; 2013 Dec; 110(50):20224-9. PubMed ID: 24277854
[TBL] [Abstract][Full Text] [Related]
16. Loss of Porcupine impairs convergent extension during gastrulation in zebrafish.
Chen Q; Takada R; Takada S
J Cell Sci; 2012 May; 125(Pt 9):2224-34. PubMed ID: 22357957
[TBL] [Abstract][Full Text] [Related]
17. Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Shah K; Panchal S; Patel B
Pharmacol Res; 2021 May; 167():105532. PubMed ID: 33677106
[TBL] [Abstract][Full Text] [Related]
18. Application of porcupine inhibitors in stem cell fate determination.
Kalantary-Charvadeh A; Hosseini V; Mehdizadeh A; Darabi M
Chem Biol Drug Des; 2020 Oct; 96(4):1052-1068. PubMed ID: 32419352
[TBL] [Abstract][Full Text] [Related]
19. Precise regulation of porcupine activity is required for physiological Wnt signaling.
Proffitt KD; Virshup DM
J Biol Chem; 2012 Oct; 287(41):34167-78. PubMed ID: 22888000
[TBL] [Abstract][Full Text] [Related]
20. Chemical Modulation of WNT Signaling in Cancer.
Zhang LS; Lum L
Prog Mol Biol Transl Sci; 2018 Jan; 153():245-269. PubMed ID: 29389519
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
