BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 35449157)

  • 1. USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma.
    Ning Z; Guo X; Liu X; Lu C; Wang A; Wang X; Wang W; Chen H; Qin W; Liu X; Zhou L; Ma C; Du J; Lin Z; Luo H; Otkur W; Qi H; Chen D; Xia T; Liu J; Tan G; Xu G; Piao HL
    Nat Commun; 2022 Apr; 13(1):2187. PubMed ID: 35449157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.
    Bhalla K; Hwang BJ; Dewi RE; Ou L; Twaddel W; Fang HB; Vafai SB; Vazquez F; Puigserver P; Boros L; Girnun GD
    Cancer Res; 2011 Nov; 71(21):6888-98. PubMed ID: 21914785
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis.
    Gu L; Zhu Y; Lin X; Lu B; Zhou X; Zhou F; Zhao Q; Prochownik EV; Li Y
    Hepatology; 2021 Jan; 73(1):160-174. PubMed ID: 32221968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma.
    Wen X; Ling S; Wu W; Shan Q; Liu P; Wang C; Wei X; Ding W; Teng X; Xu X
    Dig Dis Sci; 2020 Apr; 65(4):1064-1073. PubMed ID: 31587155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways.
    Li J; Huang Q; Long X; Zhang J; Huang X; Aa J; Yang H; Chen Z; Xing J
    J Hepatol; 2015 Dec; 63(6):1378-89. PubMed ID: 26282231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATP-citrate lyase regulates stemness and metastasis in hepatocellular carcinoma via the Wnt/β-catenin signaling pathway.
    Han Q; Chen CA; Yang W; Liang D; Lv HW; Lv GS; Zong QN; Wang HY
    Hepatobiliary Pancreat Dis Int; 2021 Jun; 20(3):251-261. PubMed ID: 33129711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polymorphisms in genes of the de novo lipogenesis pathway and overall survival of hepatocellular carcinoma patients undergoing transarterial chemoembolization.
    Wu YS; Bao DK; Dai JY; Chen C; Zhang HX; Yang Y; Xing JL; Huang XJ; Wan SG
    Asian Pac J Cancer Prev; 2015; 16(3):1051-6. PubMed ID: 25735330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
    Nelson ME; Lahiri S; Chow JD; Byrne FL; Hargett SR; Breen DS; Olzomer EM; Wu LE; Cooney GJ; Turner N; James DE; Slack-Davis JK; Lackner C; Caldwell SH; Hoehn KL
    Nat Commun; 2017 Mar; 8():14689. PubMed ID: 28290443
    [TBL] [Abstract][Full Text] [Related]  

  • 9. USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation.
    Ling S; Shan Q; Zhan Q; Ye Q; Liu P; Xu S; He X; Ma J; Xiang J; Jiang G; Wen X; Feng Z; Wu Y; Feng T; Xu L; Chen K; Zhang X; Wei R; Zhang C; Cen B; Xie H; Song P; Liu J; Zheng S; Xu X
    Gut; 2020 Jul; 69(7):1322-1334. PubMed ID: 31776228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipogenesis inhibitors: therapeutic opportunities and challenges.
    Batchuluun B; Pinkosky SL; Steinberg GR
    Nat Rev Drug Discov; 2022 Apr; 21(4):283-305. PubMed ID: 35031766
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression.
    Noh KH; Kang HM; Yoo W; Min Y; Kim D; Kim M; Wang S; Lim JH; Jung CR
    Metabolism; 2020 Sep; 110():154302. PubMed ID: 32589900
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATP citrate lyase inhibitor triggers endoplasmic reticulum stress to induce hepatocellular carcinoma cell apoptosis via p-eIF2α/ATF4/CHOP axis.
    Zheng Y; Zhou Q; Zhao C; Li J; Yu Z; Zhu Q
    J Cell Mol Med; 2021 Feb; 25(3):1468-1479. PubMed ID: 33393219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.
    Morrow MR; Batchuluun B; Wu J; Ahmadi E; Leroux JM; Mohammadi-Shemirani P; Desjardins EM; Wang Z; Tsakiridis EE; Lavoie DCT; Reihani A; Smith BK; Kwiecien JM; Lally JSV; Nero TL; Parker MW; Ask K; Scott JW; Jiang L; Paré G; Pinkosky SL; Steinberg GR
    Cell Metab; 2022 Jun; 34(6):919-936.e8. PubMed ID: 35675800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.
    Calvisi DF; Wang C; Ho C; Ladu S; Lee SA; Mattu S; Destefanis G; Delogu S; Zimmermann A; Ericsson J; Brozzetti S; Staniscia T; Chen X; Dombrowski F; Evert M
    Gastroenterology; 2011 Mar; 140(3):1071-83. PubMed ID: 21147110
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway.
    Lee JH; Jang H; Lee SM; Lee JE; Choi J; Kim TW; Cho EJ; Youn HD
    FEBS J; 2015 Jan; 282(2):361-71. PubMed ID: 25367309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells.
    Bort A; Sánchez BG; de Miguel I; Mateos-Gómez PA; Diaz-Laviada I
    Mol Biol Rep; 2020 Apr; 47(4):2635-2647. PubMed ID: 32125560
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance.
    Chang YS; Su CW; Chen SC; Chen YY; Liang YJ; Wu JC
    Cells; 2022 Feb; 11(4):. PubMed ID: 35203285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity.
    Lee KW; Cho JG; Kim CM; Kang AY; Kim M; Ahn BY; Chung SS; Lim KH; Baek KH; Sung JH; Park KS; Park SG
    J Biol Chem; 2013 Nov; 288(46):32886-96. PubMed ID: 24072712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms.
    Zaidi N; Royaux I; Swinnen JV; Smans K
    Mol Cancer Ther; 2012 Sep; 11(9):1925-35. PubMed ID: 22718913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitin-specific protease 22 promotes lipogenesis contributing to Hepatocellular Carcinoma pathogenesis.
    Xu Y; Dalamaga M; Liu J
    Metabol Open; 2022 Dec; 16():100218. PubMed ID: 36506939
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.