BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 35449354)

  • 1. Deubiquitinase USP19 enhances phenylalanine hydroxylase protein stability and its enzymatic activity.
    Sarodaya N; Tyagi A; Kim HJ; Colaco JC; Kang JS; Kim WJ; Kim KS; Ramakrishna S
    Cell Biol Toxicol; 2023 Oct; 39(5):2295-2310. PubMed ID: 35449354
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deubiquitinase USP19 extends the residual enzymatic activity of phenylalanine hydroxylase variants.
    Sarodaya N; Tyagi A; Kim HJ; Kang JS; Singh V; Hong SH; Kim WJ; Kim KS; Ramakrishna S
    Sci Rep; 2022 Aug; 12(1):14243. PubMed ID: 35987969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. E3 Ubiquitin Ligase APC/C
    Tyagi A; Sarodaya N; Kaushal K; Chandrasekaran AP; Antao AM; Suresh B; Rhie BH; Kim KS; Ramakrishna S
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33260674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New protein structures provide an updated understanding of phenylketonuria.
    Jaffe EK
    Mol Genet Metab; 2017 Aug; 121(4):289-296. PubMed ID: 28645531
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6.
    Nakamura N; Harada K; Kato M; Hirose S
    Exp Cell Res; 2014 Oct; 328(1):207-216. PubMed ID: 25088257
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations.
    Scheller R; Stein A; Nielsen SV; Marin FI; Gerdes AM; Di Marco M; Papaleo E; Lindorff-Larsen K; Hartmann-Petersen R
    Hum Mutat; 2019 Apr; 40(4):444-457. PubMed ID: 30648773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phenylalanine hydroxylase deficiency in the Slovak population: genotype-phenotype correlations and genotype-based predictions of BH4-responsiveness.
    Polak E; Ficek A; Radvanszky J; Soltysova A; Urge O; Cmelova E; Kantarska D; Kadasi L
    Gene; 2013 Sep; 526(2):347-55. PubMed ID: 23764561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tetrahydrobiopterin protects phenylalanine hydroxylase activity in vivo: implications for tetrahydrobiopterin-responsive hyperphenylalaninemia.
    Thöny B; Ding Z; Martínez A
    FEBS Lett; 2004 Nov; 577(3):507-11. PubMed ID: 15556637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in the phenylalanine hydroxylase gene: genetic determinants for the phenotypic variability of hyperphenylalaninemia.
    Güttler F; Guldberg P
    Acta Paediatr Suppl; 1994 Dec; 407():49-56. PubMed ID: 7766959
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phenylalanine hydroxylase: function, structure, and regulation.
    Flydal MI; Martinez A
    IUBMB Life; 2013 Apr; 65(4):341-9. PubMed ID: 23457044
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase.
    Aubi O; Prestegård KS; Jung-Kc K; Shi TS; Ying M; Grindheim AK; Scherer T; Ulvik A; McCann A; Spriet E; Thöny B; Martinez A
    Nat Commun; 2021 Apr; 12(1):2073. PubMed ID: 33824313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of phenylketonuria missense substitutions, distant from the phenylalanine hydroxylase active site, illustrates a paradigm for mechanism and potential modulation of phenotype.
    Waters PJ; Parniak MA; Akerman BR; Scriver CR
    Mol Genet Metab; 2000 Feb; 69(2):101-10. PubMed ID: 10720436
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase.
    Arturo EC; Merkel GW; Hansen MR; Lisowski S; Almeida D; Gupta K; Jaffe EK
    Biochimie; 2021 Apr; 183():63-77. PubMed ID: 33221376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SIAH1 modulates antiviral immune responses by targeting deubiquitinase USP19.
    Weerawardhana A; Herath TUB; Gayan Chathuranga WA; Kim TH; Ekanayaka P; Chathuranga K; Kang HC; Jung JU; Lee JS
    J Med Virol; 2024 Mar; 96(3):e29523. PubMed ID: 38483060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional Characterization of Novel Phenylalanine Hydroxylase p.Gln226Lys Mutation Revealed Its Non-responsiveness to Tetrahydrobiopterin Treatment in Hepatoma Cellular Model.
    Klaassen K; Djordjevic M; Skakic A; Desviat LR; Pavlovic S; Perez B; Stojiljkovic M
    Biochem Genet; 2018 Oct; 56(5):533-541. PubMed ID: 29654578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impact of the phenylalanine hydroxylase gene on maternal phenylketonuria outcome.
    Güttler F; Azen C; Guldberg P; Romstad A; Hanley WB; Levy HL; Matalon R; Rouse BM; Trefz F; de la Cruz F; Koch R
    Pediatrics; 2003 Dec; 112(6 Pt 2):1530-3. PubMed ID: 14654659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2.
    Mei Y; Hahn AA; Hu S; Yang X
    J Biol Chem; 2011 Oct; 286(41):35380-35387. PubMed ID: 21849505
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human phenylalanine hydroxylase mutations and hyperphenylalaninemia phenotypes: a metanalysis of genotype-phenotype correlations.
    Kayaalp E; Treacy E; Waters PJ; Byck S; Nowacki P; Scriver CR
    Am J Hum Genet; 1997 Dec; 61(6):1309-17. PubMed ID: 9399896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vivo studies of phenylalanine hydroxylase by phenylalanine breath test: diagnosis of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency.
    Okano Y; Hase Y; Kawajiri M; Nishi Y; Inui K; Sakai N; Tanaka Y; Takatori K; Kajiwara M; Yamano T
    Pediatr Res; 2004 Nov; 56(5):714-9. PubMed ID: 15319459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.