BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 35452600)

  • 1. The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
    Wenes M; Jaccard A; Wyss T; Maldonado-Pérez N; Teoh ST; Lepez A; Renaud F; Franco F; Waridel P; Yacoub Maroun C; Tschumi B; Dumauthioz N; Zhang L; Donda A; Martín F; Migliorini D; Lunt SY; Ho PC; Romero P
    Cell Metab; 2022 May; 34(5):731-746.e9. PubMed ID: 35452600
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier.
    Zangari J; Petrelli F; Maillot B; Martinou JC
    Biomolecules; 2020 Jul; 10(7):. PubMed ID: 32708919
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism.
    Cui J; Quan M; Xie D; Gao Y; Guha S; Fallon MB; Chen J; Xie K
    Oncogene; 2020 Jan; 39(5):1140-1151. PubMed ID: 31641207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heart failure-emerging roles for the mitochondrial pyruvate carrier.
    Fernandez-Caggiano M; Eaton P
    Cell Death Differ; 2021 Apr; 28(4):1149-1158. PubMed ID: 33473180
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
    Le XH; Lee CP; Millar AH
    Plant Cell; 2021 Aug; 33(8):2776-2793. PubMed ID: 34137858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.
    Schell JC; Wisidagama DR; Bensard C; Zhao H; Wei P; Tanner J; Flores A; Mohlman J; Sorensen LK; Earl CS; Olson KA; Miao R; Waller TC; Delker D; Kanth P; Jiang L; DeBerardinis RJ; Bronner MP; Li DY; Cox JE; Christofk HR; Lowry WE; Thummel CS; Rutter J
    Nat Cell Biol; 2017 Sep; 19(9):1027-1036. PubMed ID: 28812582
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of novel MPC1 gene variants causing mitochondrial pyruvate carrier deficiency.
    Jiang H; Alahmad A; Fu S; Fu X; Liu Z; Han X; Li L; Song T; Xu M; Liu S; Wang J; Albash B; Alaqeel A; Catalina V; Prokisch H; Taylor RW; McFarland R; Fang F
    J Inherit Metab Dis; 2022 Mar; 45(2):264-277. PubMed ID: 34873722
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
    Nancolas B; Guo L; Zhou R; Nath K; Nelson DS; Leeper DB; Blair IA; Glickson JD; Halestrap AP
    Biochem J; 2016 Apr; 473(7):929-36. PubMed ID: 26831515
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan.
    Buchanan JL; Taylor EB
    Biomolecules; 2020 Aug; 10(8):. PubMed ID: 32784379
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC.
    Arce-Molina R; Cortés-Molina F; Sandoval PY; Galaz A; Alegría K; Schirmeier S; Barros LF; San Martín A
    Elife; 2020 Mar; 9():. PubMed ID: 32142409
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
    Cluntun AA; Badolia R; Lettlova S; Parnell KM; Shankar TS; Diakos NA; Olson KA; Taleb I; Tatum SM; Berg JA; Cunningham CN; Van Ry T; Bott AJ; Krokidi AT; Fogarty S; Skedros S; Swiatek WI; Yu X; Luo B; Merx S; Navankasattusas S; Cox JE; Ducker GS; Holland WL; McKellar SH; Rutter J; Drakos SG
    Cell Metab; 2021 Mar; 33(3):629-648.e10. PubMed ID: 33333007
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
    Ramstead AG; Wallace JA; Lee SH; Bauer KM; Tang WW; Ekiz HA; Lane TE; Cluntun AA; Bettini ML; Round JL; Rutter J; O'Connell RM
    Cell Rep; 2020 Mar; 30(9):2889-2899.e6. PubMed ID: 32130894
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glycolytic potential enhanced by blockade of pyruvate influx into mitochondria sensitizes prostate cancer to detection and radiotherapy.
    Xu H; Chen J; Cao Z; Chen X; Huang C; Ji J; Xu Y; Jiang J; Wang Y; Xu G; Zhou L; He J; Wei X; Wu JB; Wang Z; Ren S; Wang F
    Cancer Biol Med; 2022 Aug; 19(9):1315-33. PubMed ID: 35972052
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.
    Corbet C; Bastien E; Draoui N; Doix B; Mignion L; Jordan BF; Marchand A; Vanherck JC; Chaltin P; Schakman O; Becker HM; Riant O; Feron O
    Nat Commun; 2018 Mar; 9(1):1208. PubMed ID: 29572438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice.
    Hodges WT; Jarasvaraparn C; Ferguson D; Griffett K; Gill LE; Chen Y; Ilagan MXG; Hegazy L; Elgendy B; Cho K; Patti GJ; McCommis KS; Finck BN
    J Biol Chem; 2022 Feb; 298(2):101554. PubMed ID: 34973337
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mitochondrial pyruvate carrier at the crossroads of intermediary metabolism.
    Yiew NKH; Finck BN
    Am J Physiol Endocrinol Metab; 2022 Jul; 323(1):E33-E52. PubMed ID: 35635330
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.
    De La Rossa A; Laporte MH; Astori S; Marissal T; Montessuit S; Sheshadri P; Ramos-Fernández E; Mendez P; Khani A; Quairiaux C; Taylor EB; Rutter J; Nunes JM; Carleton A; Duchen MR; Sandi C; Martinou JC
    Elife; 2022 Feb; 11():. PubMed ID: 35188099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity.
    Gray LR; Rauckhorst AJ; Taylor EB
    J Biol Chem; 2016 Apr; 291(14):7409-17. PubMed ID: 26823462
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition.
    Tavoulari S; Sichrovsky M; Kunji ERS
    Acta Physiol (Oxf); 2023 Aug; 238(4):e14016. PubMed ID: 37366179
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial pyruvate carrier-mediated metabolism is dispensable for the classical activation of macrophages.
    Ran L; Zhang S; Wang G; Zhao P; Sun J; Zhou J; Gan H; Jeon R; Li Q; Herrmann J; Wang F
    Nat Metab; 2023 May; 5(5):804-820. PubMed ID: 37188821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.