209 related articles for article (PubMed ID: 35452684)
1. Regulator of G protein signaling 2 inhibits Gα
Zhang Q; Haak AJ; Sjögren B
J Biol Chem; 2022 Jun; 298(6):101955. PubMed ID: 35452684
[TBL] [Abstract][Full Text] [Related]
2. Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.
Anger T; Zhang W; Mende U
J Biol Chem; 2004 Feb; 279(6):3906-15. PubMed ID: 14630933
[TBL] [Abstract][Full Text] [Related]
3. Structure of the Regulator of G Protein Signaling 8 (RGS8)-Gαq Complex: MOLECULAR BASIS FOR Gα SELECTIVITY.
Taylor VG; Bommarito PA; Tesmer JJ
J Biol Chem; 2016 Mar; 291(10):5138-45. PubMed ID: 26755720
[TBL] [Abstract][Full Text] [Related]
4. Atypical activation of the G protein Gα
Maziarz M; Leyme A; Marivin A; Luebbers A; Patel PP; Chen Z; Sprang SR; Garcia-Marcos M
J Biol Chem; 2018 Dec; 293(51):19586-19599. PubMed ID: 30352874
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and evaluation of quinazoline derivatives as Gαq/11 proteins inhibitors against uveal melanoma.
Fan G; Liu L; Ye J; Xiao W; Xiong XF
Bioorg Chem; 2024 Feb; 143():107005. PubMed ID: 38043397
[TBL] [Abstract][Full Text] [Related]
6. Direct targeting of Gα
Annala S; Feng X; Shridhar N; Eryilmaz F; Patt J; Yang J; Pfeil EM; Cervantes-Villagrana RD; Inoue A; Häberlein F; Slodczyk T; Reher R; Kehraus S; Monteleone S; Schrage R; Heycke N; Rick U; Engel S; Pfeifer A; Kolb P; König G; Bünemann M; Tüting T; Vázquez-Prado J; Gutkind JS; Gaffal E; Kostenis E
Sci Signal; 2019 Mar; 12(573):. PubMed ID: 30890659
[TBL] [Abstract][Full Text] [Related]
7. Disruption of the interaction between mutationally activated Gα
Aumiller JL; Wedegaertner PB
J Biol Chem; 2023 Feb; 299(2):102880. PubMed ID: 36626984
[TBL] [Abstract][Full Text] [Related]
8. IGF1R Inhibition Enhances the Therapeutic Effects of Gq/11 Inhibition in Metastatic Uveal Melanoma Progression.
Lapadula D; Lam B; Terai M; Sugase T; Tanaka R; Farias E; Kadamb R; Lopez-Anton M; Heine CC; Modasia B; Aguirre-Ghiso JA; Aplin AE; Sato T; Benovic JL
Mol Cancer Ther; 2023 Jan; 22(1):63-74. PubMed ID: 36223548
[TBL] [Abstract][Full Text] [Related]
9. Regulation of cardiomyocyte signaling by RGS proteins: differential selectivity towards G proteins and susceptibility to regulation.
Hao J; Michalek C; Zhang W; Zhu M; Xu X; Mende U
J Mol Cell Cardiol; 2006 Jul; 41(1):51-61. PubMed ID: 16756988
[TBL] [Abstract][Full Text] [Related]
10. Combined Inhibition of Gα
Hitchman TD; Bayshtok G; Ceraudo E; Moore AR; Lee C; Jia R; Wang N; Pachai MR; Shoushtari AN; Francis JH; Guan Y; Chen J; Chang MT; Taylor BS; Sakmar TP; Huber T; Chi P; Chen Y
Clin Cancer Res; 2021 Mar; 27(5):1476-1490. PubMed ID: 33229459
[TBL] [Abstract][Full Text] [Related]
11. Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.
Baqai U; Kurimchak AM; Trachtenberg IV; Purwin TJ; Haj JI; Han A; Luo K; Pachon NF; Jeon A; Chua V; Davies MA; Gutkind JS; Benovic JL; Duncan JS; Aplin AE
J Biol Chem; 2023 Dec; 299(12):105418. PubMed ID: 37923138
[TBL] [Abstract][Full Text] [Related]
12. Structural and functional analysis of the regulator of G protein signaling 2-gαq complex.
Nance MR; Kreutz B; Tesmer VM; Sterne-Marr R; Kozasa T; Tesmer JJ
Structure; 2013 Mar; 21(3):438-48. PubMed ID: 23434405
[TBL] [Abstract][Full Text] [Related]
13. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.
Feng X; Degese MS; Iglesias-Bartolome R; Vaque JP; Molinolo AA; Rodrigues M; Zaidi MR; Ksander BR; Merlino G; Sodhi A; Chen Q; Gutkind JS
Cancer Cell; 2014 Jun; 25(6):831-45. PubMed ID: 24882515
[TBL] [Abstract][Full Text] [Related]
14. Dynamics of Gαq-protein-p63RhoGEF interaction and its regulation by RGS2.
Bodmann EL; Rinne A; Brandt D; Lutz S; Wieland T; Grosse R; Bünemann M
Biochem J; 2014 Feb; 458(1):131-40. PubMed ID: 24299002
[TBL] [Abstract][Full Text] [Related]
15. Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells.
Cao X; Qin J; Xie Y; Khan O; Dowd F; Scofield M; Lin MF; Tu Y
Oncogene; 2006 Jun; 25(26):3719-34. PubMed ID: 16449965
[TBL] [Abstract][Full Text] [Related]
16. Functional characterization of uveal melanoma oncogenes.
Ma J; Weng L; Bastian BC; Chen X
Oncogene; 2021 Jan; 40(4):806-820. PubMed ID: 33262460
[TBL] [Abstract][Full Text] [Related]
17. Interplay between negative and positive design elements in Gα helical domains of G proteins determines interaction specificity toward RGS2.
Kasom M; Gharra S; Sadiya I; Avital-Shacham M; Kosloff M
Biochem J; 2018 Jul; 475(14):2293-2304. PubMed ID: 29925530
[TBL] [Abstract][Full Text] [Related]
18. Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.
Ghil S; McCoy KL; Hepler JR
PLoS One; 2014; 9(4):e95355. PubMed ID: 24743392
[TBL] [Abstract][Full Text] [Related]
19. Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein.
Shi J; Damjanoska KJ; Zemaitaitis B; Garcia F; Carrasco G; Sullivan NR; She Y; Young KH; Battaglia G; Van De kar LD; Howland DS; Muma NA
Neuropharmacology; 2006 Sep; 51(3):524-35. PubMed ID: 16769091
[TBL] [Abstract][Full Text] [Related]
20. Design, Synthesis, and Evaluation of Small Molecule Gαq/11 Protein Inhibitors for the Treatment of Uveal Melanoma.
Ge Y; Shi S; Deng JJ; Chen XP; Song Z; Liu L; Lou L; Zhang X; Xiong XF
J Med Chem; 2021 Mar; 64(6):3131-3152. PubMed ID: 33715360
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]