BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 35453346)

  • 1. BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer.
    Lv Y; Lv X; Zhang J; Cao G; Xu C; Zhang B; Lin W
    Antioxidants (Basel); 2022 Mar; 11(4):. PubMed ID: 35453346
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.
    Hussong M; Börno ST; Kerick M; Wunderlich A; Franz A; Sültmann H; Timmermann B; Lehrach H; Hirsch-Kauffmann M; Schweiger MR
    Cell Death Dis; 2014 Apr; 5(4):e1195. PubMed ID: 24763052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BRD4 contributes to high-glucose-induced podocyte injury by modulating Keap1/Nrf2/ARE signaling.
    Zuo H; Wang S; Feng J; Liu X
    Biochimie; 2019 Oct; 165():100-107. PubMed ID: 31325480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-146b-5p protects oligodendrocyte precursor cells from oxygen/glucose deprivation-induced injury through regulating Keap1/Nrf2 signaling via targeting bromodomain-containing protein 4.
    Li X; Zhang W; Xiao M; Wang F; Zhou P; Yang J; Chen X
    Biochem Biophys Res Commun; 2019 Jun; 513(4):875-882. PubMed ID: 31003769
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of bromodomain-containing protein 4 protects trophoblast cells from oxidative stress injury by enhancing Nrf2 activation.
    Wu Y; Mi Y; Zhang F; Cheng Y; Wu X
    Hum Exp Toxicol; 2021 May; 40(5):742-753. PubMed ID: 33094643
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in
    Galan-Cobo A; Sitthideatphaiboon P; Qu X; Poteete A; Pisegna MA; Tong P; Chen PH; Boroughs LK; Rodriguez MLM; Zhang W; Parlati F; Wang J; Gandhi V; Skoulidis F; DeBerardinis RJ; Minna JD; Heymach JV
    Cancer Res; 2019 Jul; 79(13):3251-3267. PubMed ID: 31040157
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment.
    Best SA; De Souza DP; Kersbergen A; Policheni AN; Dayalan S; Tull D; Rathi V; Gray DH; Ritchie ME; McConville MJ; Sutherland KD
    Cell Metab; 2018 Apr; 27(4):935-943.e4. PubMed ID: 29526543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
    Singh A; Misra V; Thimmulappa RK; Lee H; Ames S; Hoque MO; Herman JG; Baylin SB; Sidransky D; Gabrielson E; Brock MV; Biswal S
    PLoS Med; 2006 Oct; 3(10):e420. PubMed ID: 17020408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Keap1-Nrf2 Interaction Suppresses Cell Motility in Lung Adenocarcinomas by Targeting the S100P Protein.
    Chien MH; Lee WJ; Hsieh FK; Li CF; Cheng TY; Wang MY; Chen JS; Chow JM; Jan YH; Hsiao M; Hua KT; Kuo ML
    Clin Cancer Res; 2015 Oct; 21(20):4719-32. PubMed ID: 26078391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
    Hori R; Yamaguchi K; Sato H; Watanabe M; Tsutsumi K; Iwamoto S; Abe M; Onodera H; Nakamura S; Nakai R
    Cancer Med; 2019 Mar; 8(3):1157-1168. PubMed ID: 30735010
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.
    Namani A; Matiur Rahaman M; Chen M; Tang X
    BMC Cancer; 2018 Jan; 18(1):46. PubMed ID: 29306329
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenetic Therapeutics Targeting NRF2/KEAP1 Signaling in Cancer Oxidative Stress.
    Zhang S; Duan S; Xie Z; Bao W; Xu B; Yang W; Zhou L
    Front Pharmacol; 2022; 13():924817. PubMed ID: 35754474
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucose availability is a decisive factor for Nrf2-mediated gene expression.
    Heiss EH; Schachner D; Zimmermann K; Dirsch VM
    Redox Biol; 2013; 1(1):359-65. PubMed ID: 24024172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the cell signaling pathway Keap1-Nrf2 as a therapeutic strategy for adenocarcinomas of the lung.
    Zhang B; Ma Z; Tan B; Lin N
    Expert Opin Ther Targets; 2019 Mar; 23(3):241-250. PubMed ID: 30556750
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.
    Gao Z; Yuan T; Zhou X; Ni P; Sun G; Li P; Cheng Z; Wang X
    Cancer Biol Ther; 2018 May; 19(5):407-415. PubMed ID: 29333921
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
    Sakai E; Morita M; Ohuchi M; Kido MA; Fukuma Y; Nishishita K; Okamoto K; Itoh K; Yamamoto M; Tsukuba T
    FASEB J; 2017 Sep; 31(9):4011-4022. PubMed ID: 28515152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KEAP1/NRF2 (NFE2L2) mutations in NSCLC - Fuel for a superresistant phenotype?
    Dempke WCM; Reck M
    Lung Cancer; 2021 Sep; 159():10-17. PubMed ID: 34303275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.
    Ding H; Chen Z; Wu K; Huang SM; Wu WL; LeBoeuf SE; Pillai RG; Rabinowitz JD; Papagiannakopoulos T
    Sci Adv; 2021 Nov; 7(47):eabk1023. PubMed ID: 34788087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis.
    Mohs A; Otto T; Schneider KM; Peltzer M; Boekschoten M; Holland CH; Hudert CA; Kalveram L; Wiegand S; Saez-Rodriguez J; Longerich T; Hengstler JG; Trautwein C
    J Hepatol; 2021 Mar; 74(3):638-648. PubMed ID: 33342543
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fuzzy complex formation between the intrinsically disordered prothymosin α and the Kelch domain of Keap1 involved in the oxidative stress response.
    Khan H; Cino EA; Brickenden A; Fan J; Yang D; Choy WY
    J Mol Biol; 2013 Mar; 425(6):1011-27. PubMed ID: 23318954
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.