228 related articles for article (PubMed ID: 35454159)
1. Propofol, an Anesthetic Agent, Inhibits HCN Channels through the Allosteric Modulation of the cAMP-Dependent Gating Mechanism.
Shimizu M; Mi X; Toyoda F; Kojima A; Ding WG; Fukushima Y; Omatsu-Kanbe M; Kitagawa H; Matsuura H
Biomolecules; 2022 Apr; 12(4):. PubMed ID: 35454159
[TBL] [Abstract][Full Text] [Related]
2. The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms.
Wang ZJ; Blanco I; Hayoz S; Brelidze TI
J Biol Chem; 2020 Jun; 295(24):8164-8173. PubMed ID: 32341127
[TBL] [Abstract][Full Text] [Related]
3. Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: ligand-independent relief of autoinhibition in HCN4.
Liao Z; Lockhead D; St Clair JR; Larson ED; Wilson CE; Proenza C
J Gen Physiol; 2012 Nov; 140(5):557-66. PubMed ID: 23109717
[TBL] [Abstract][Full Text] [Related]
4. Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions.
Wang J; Chen S; Siegelbaum SA
J Gen Physiol; 2001 Sep; 118(3):237-50. PubMed ID: 11524455
[TBL] [Abstract][Full Text] [Related]
5. The structure of the apo cAMP-binding domain of HCN4 - a stepping stone toward understanding the cAMP-dependent modulation of the hyperpolarization-activated cyclic-nucleotide-gated ion channels.
Akimoto M; VanSchouwen B; Melacini G
FEBS J; 2018 Jun; 285(12):2182-2192. PubMed ID: 29444387
[TBL] [Abstract][Full Text] [Related]
6. A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
Akimoto M; Zhang Z; Boulton S; Selvaratnam R; VanSchouwen B; Gloyd M; Accili EA; Lange OF; Melacini G
J Biol Chem; 2014 Aug; 289(32):22205-20. PubMed ID: 24878962
[TBL] [Abstract][Full Text] [Related]
7. Flavonoid regulation of HCN2 channels.
Carlson AE; Rosenbaum JC; Brelidze TI; Klevit RE; Zagotta WN
J Biol Chem; 2013 Nov; 288(46):33136-45. PubMed ID: 24085296
[TBL] [Abstract][Full Text] [Related]
8. The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
Porro A; Saponaro A; Gasparri F; Bauer D; Gross C; Pisoni M; Abbandonato G; Hamacher K; Santoro B; Thiel G; Moroni A
Elife; 2019 Nov; 8():. PubMed ID: 31769408
[TBL] [Abstract][Full Text] [Related]
9. Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.
Chen S; Wang J; Zhou L; George MS; Siegelbaum SA
J Gen Physiol; 2007 Feb; 129(2):175-88. PubMed ID: 17261842
[TBL] [Abstract][Full Text] [Related]
10. Integrated allosteric model of voltage gating of HCN channels.
Altomare C; Bucchi A; Camatini E; Baruscotti M; Viscomi C; Moroni A; DiFrancesco D
J Gen Physiol; 2001 Jun; 117(6):519-32. PubMed ID: 11382803
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Saponaro A; Pauleta SR; Cantini F; Matzapetakis M; Hammann C; Donadoni C; Hu L; Thiel G; Banci L; Santoro B; Moroni A
Proc Natl Acad Sci U S A; 2014 Oct; 111(40):14577-82. PubMed ID: 25197093
[TBL] [Abstract][Full Text] [Related]
12. Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.
Han Y; Noam Y; Lewis AS; Gallagher JJ; Wadman WJ; Baram TZ; Chetkovich DM
J Biol Chem; 2011 Jun; 286(23):20823-34. PubMed ID: 21504900
[TBL] [Abstract][Full Text] [Related]
13. Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
Lolicato M; Nardini M; Gazzarrini S; Möller S; Bertinetti D; Herberg FW; Bolognesi M; Martin H; Fasolini M; Bertrand JA; Arrigoni C; Thiel G; Moroni A
J Biol Chem; 2011 Dec; 286(52):44811-20. PubMed ID: 22006928
[TBL] [Abstract][Full Text] [Related]
14. Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels.
VanSchouwen B; Akimoto M; Sayadi M; Fogolari F; Melacini G
J Biol Chem; 2015 Jul; 290(29):17642-17654. PubMed ID: 25944904
[TBL] [Abstract][Full Text] [Related]
15. Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia.
Boulton S; Akimoto M; Akbarizadeh S; Melacini G
J Biol Chem; 2017 Apr; 292(15):6414-6428. PubMed ID: 28174302
[TBL] [Abstract][Full Text] [Related]
16. Propofol inhibits HCN1 pacemaker channels by selective association with the closed states of the membrane embedded channel core.
Lyashchenko AK; Redd KJ; Yang J; Tibbs GR
J Physiol; 2007 Aug; 583(Pt 1):37-56. PubMed ID: 17569731
[TBL] [Abstract][Full Text] [Related]
17. Activation gating in HCN2 channels.
Hummert S; Thon S; Eick T; Schmauder R; Schulz E; Benndorf K
PLoS Comput Biol; 2018 Mar; 14(3):e1006045. PubMed ID: 29565972
[TBL] [Abstract][Full Text] [Related]
18. Anisotropic Network Analysis of Open/Closed HCN4 Channel Advocates Asymmetric Subunit Cooperativity in cAMP Modulation of Gating.
Kunzmann P; Krumbach JH; Saponaro A; Moroni A; Thiel G; Hamacher K
J Chem Inf Model; 2024 Jun; 64(12):4727-4738. PubMed ID: 38830626
[TBL] [Abstract][Full Text] [Related]
19. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Saponaro A; Cantini F; Porro A; Bucchi A; DiFrancesco D; Maione V; Donadoni C; Introini B; Mesirca P; Mangoni ME; Thiel G; Banci L; Santoro B; Moroni A
Elife; 2018 Jun; 7():. PubMed ID: 29923826
[TBL] [Abstract][Full Text] [Related]
20. HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.
Chen X; Sirois JE; Lei Q; Talley EM; Lynch C; Bayliss DA
J Neurosci; 2005 Jun; 25(24):5803-14. PubMed ID: 15958747
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]