BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 35456491)

  • 1. High Concentration or Combined Treatment of Antisense Oligonucleotides for Spinal Muscular Atrophy Perturbed
    Wijaya YOS; Niba ETE; Nishio H; Okamoto K; Awano H; Saito T; Takeshima Y; Shinohara M
    Genes (Basel); 2022 Apr; 13(4):. PubMed ID: 35456491
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells.
    Pagliarini V; Guerra M; Di Rosa V; Compagnucci C; Sette C
    J Neurochem; 2020 Apr; 153(2):264-275. PubMed ID: 31811660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combinatorial treatment for spinal muscular atrophy: An Editorial for 'Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells' on page 264.
    Poletti A; Fischbeck KH
    J Neurochem; 2020 Apr; 153(2):146-149. PubMed ID: 32056234
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes.
    Singh RN; Singh NN
    Adv Neurobiol; 2018; 20():31-61. PubMed ID: 29916015
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A short antisense oligonucleotide masking a unique intronic motif prevents skipping of a critical exon in spinal muscular atrophy.
    Singh NN; Shishimorova M; Cao LC; Gangwani L; Singh RN
    RNA Biol; 2009; 6(3):341-50. PubMed ID: 19430205
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of
    Toosaranont J; Ruschadaariyachat S; Mujchariyakul W; Arora JK; Charoensawan V; Suktitipat B; Palmer TN; Fletcher S; Wilton SD; Mitrpant C
    Int J Mol Sci; 2022 Apr; 23(7):. PubMed ID: 35409296
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High Concentration of an ISS-N1-Targeting Antisense Oligonucleotide Causes Massive Perturbation of the Transcriptome.
    Ottesen EW; Luo D; Singh NN; Singh RN
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445083
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of combined systemic and local morpholino treatment on the spinal muscular atrophy Δ7 mouse model phenotype.
    Nizzardo M; Simone C; Salani S; Ruepp MD; Rizzo F; Ruggieri M; Zanetta C; Brajkovic S; Moulton HM; Müehlemann O; Bresolin N; Comi GP; Corti S
    Clin Ther; 2014 Mar; 36(3):340-56.e5. PubMed ID: 24636820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanistic principles of antisense targets for the treatment of spinal muscular atrophy.
    Singh NN; Lee BM; DiDonato CJ; Singh RN
    Future Med Chem; 2015; 7(13):1793-808. PubMed ID: 26381381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA.
    Dominguez CE; Cunningham D; Venkataramany AS; Chandler DS
    Hum Genet; 2022 Feb; 141(2):239-256. PubMed ID: 35088120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron.
    Singh NK; Singh NN; Androphy EJ; Singh RN
    Mol Cell Biol; 2006 Feb; 26(4):1333-46. PubMed ID: 16449646
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evolving concepts on human SMN pre-mRNA splicing.
    Singh RN
    RNA Biol; 2007; 4(1):7-10. PubMed ID: 17592254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy.
    Touznik A; Maruyama R; Yokota T
    Methods Mol Biol; 2018; 1828():439-454. PubMed ID: 30171558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual masking of specific negative splicing regulatory elements resulted in maximal exon 7 inclusion of SMN2 gene.
    Pao PW; Wee KB; Yee WC; Pramono ZA
    Mol Ther; 2014 Apr; 22(4):854-61. PubMed ID: 24317636
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of Cell-Penetrating Peptide Delivery of Antisense Oligonucleotides for Therapeutic Efficacy in Spinal Muscular Atrophy.
    Hammond SM; Abendroth F; Gait MJ; Wood MJA
    Methods Mol Biol; 2019; 2036():221-236. PubMed ID: 31410800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions.
    Singh NN; Lee BM; Singh RN
    Ann N Y Acad Sci; 2015 Apr; 1341():176-87. PubMed ID: 25727246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice.
    Hua Y; Vickers TA; Okunola HL; Bennett CF; Krainer AR
    Am J Hum Genet; 2008 Apr; 82(4):834-48. PubMed ID: 18371932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nusinersen in the Treatment of Spinal Muscular Atrophy.
    Goodkey K; Aslesh T; Maruyama R; Yokota T
    Methods Mol Biol; 2018; 1828():69-76. PubMed ID: 30171535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.
    d'Ydewalle C; Ramos DM; Pyles NJ; Ng SY; Gorz M; Pilato CM; Ling K; Kong L; Ward AJ; Rubin LL; Rigo F; Bennett CF; Sumner CJ
    Neuron; 2017 Jan; 93(1):66-79. PubMed ID: 28017471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophy.
    Mitrpant C; Porensky P; Zhou H; Price L; Muntoni F; Fletcher S; Wilton SD; Burghes AH
    PLoS One; 2013; 8(4):e62114. PubMed ID: 23630626
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.