BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 35460832)

  • 41. Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.
    Hegazy AM; Yamada D; Kobayashi M; Kohno S; Ueno M; Ali MA; Ohta K; Tadokoro Y; Ino Y; Todo T; Soga T; Takahashi C; Hirao A
    J Biol Chem; 2016 Oct; 291(41):21496-21509. PubMed ID: 27519418
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.
    Liu Q; Kirubakaran S; Hur W; Niepel M; Westover K; Thoreen CC; Wang J; Ni J; Patricelli MP; Vogel K; Riddle S; Waller DL; Traynor R; Sanda T; Zhao Z; Kang SA; Zhao J; Look AT; Sorger PK; Sabatini DM; Gray NS
    J Biol Chem; 2012 Mar; 287(13):9742-9752. PubMed ID: 22223645
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling.
    Fumarola C; Caffarra C; La Monica S; Galetti M; Alfieri RR; Cavazzoni A; Galvani E; Generali D; Petronini PG; Bonelli MA
    Breast Cancer Res Treat; 2013 Aug; 141(1):67-78. PubMed ID: 23963659
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling.
    Chen Y; Wei H; Liu F; Guan JL
    J Biol Chem; 2014 Jan; 289(2):1164-73. PubMed ID: 24275666
    [TBL] [Abstract][Full Text] [Related]  

  • 45. A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.
    Liu P; Ge M; Hu J; Li X; Che L; Sun K; Cheng L; Huang Y; Pilo MG; Cigliano A; Pes GM; Pascale RM; Brozzetti S; Vidili G; Porcu A; Cossu A; Palmieri G; Sini MC; Ribback S; Dombrowski F; Tao J; Calvisi DF; Chen L; Chen X
    Hepatology; 2017 Jul; 66(1):167-181. PubMed ID: 28370287
    [TBL] [Abstract][Full Text] [Related]  

  • 46. NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.
    Zha X; Hu Z; Ji S; Jin F; Jiang K; Li C; Zhao P; Tu Z; Chen X; Di L; Zhou H; Zhang H
    Cancer Lett; 2015 Apr; 359(1):97-106. PubMed ID: 25578782
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1.
    Ghomlaghi M; Yang G; Shin SY; James DE; Nguyen LK
    PLoS Comput Biol; 2021 Sep; 17(9):e1008513. PubMed ID: 34529665
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer.
    White MA; Lin C; Rajapakshe K; Dong J; Shi Y; Tsouko E; Mukhopadhyay R; Jasso D; Dawood W; Coarfa C; Frigo DE
    Mol Cancer Res; 2017 Aug; 15(8):1017-1028. PubMed ID: 28507054
    [TBL] [Abstract][Full Text] [Related]  

  • 49. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.
    Ben-Hur V; Denichenko P; Siegfried Z; Maimon A; Krainer A; Davidson B; Karni R
    Cell Rep; 2013 Jan; 3(1):103-15. PubMed ID: 23273915
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer.
    Li H; Lin J; Wang X; Yao G; Wang L; Zheng H; Yang C; Jia C; Liu A; Bai X
    Breast Cancer Res Treat; 2012 Aug; 134(3):1057-66. PubMed ID: 22476852
    [TBL] [Abstract][Full Text] [Related]  

  • 51. The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells.
    Alayev A; Berger SM; Kramer MY; Schwartz NS; Holz MK
    J Cell Biochem; 2015 Mar; 116(3):450-7. PubMed ID: 25336146
    [TBL] [Abstract][Full Text] [Related]  

  • 52. mTORC1 and -2 Coordinate Transcriptional and Translational Reprogramming in Resistance to DNA Damage and Replicative Stress in Breast Cancer Cells.
    Silvera D; Ernlund A; Arju R; Connolly E; Volta V; Wang J; Schneider RJ
    Mol Cell Biol; 2017 Mar; 37(5):. PubMed ID: 27956700
    [TBL] [Abstract][Full Text] [Related]  

  • 53. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.
    Zhang D; Contu R; Latronico MV; Zhang J; Rizzi R; Catalucci D; Miyamoto S; Huang K; Ceci M; Gu Y; Dalton ND; Peterson KL; Guan KL; Brown JH; Chen J; Sonenberg N; Condorelli G
    J Clin Invest; 2010 Aug; 120(8):2805-16. PubMed ID: 20644257
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
    Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
    Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress.
    Zhou Y; Liang X; Chang H; Shu F; Wu Y; Zhang T; Fu Y; Zhang Q; Zhu JD; Mi M
    Cancer Sci; 2014 Oct; 105(10):1279-87. PubMed ID: 25088800
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Apoptosis induced by PGC-1β in breast cancer cells is mediated by the mTOR pathway.
    Wang L; Liu Q; Li F; Qiu J; Fan H; Ma H; Zhu Y; Wu L; Han X; Yang Z; Jiang H; Wei J; Xia H
    Oncol Rep; 2013 Oct; 30(4):1631-8. PubMed ID: 23877360
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Hepatocyte growth factor protects pulmonary endothelial barrier against oxidative stress and mitochondria-dependent apoptosis.
    Meng S; Xia F; Xu J; Zhang X; Xue M; Gu M; Guo F; Huang Y; Qiu H; Yang Y
    Chin Med J (Engl); 2022 Apr; 135(7):837-848. PubMed ID: 35671182
    [TBL] [Abstract][Full Text] [Related]  

  • 58. MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.
    Mancini F; Teveroni E; Di Conza G; Monteleone V; Arisi I; Pellegrino M; Buttarelli M; Pieroni L; D'Onofrio M; Urbani A; Pontecorvi A; Mazzone M; Moretti F
    Mol Cancer; 2017 Mar; 16(1):55. PubMed ID: 28270148
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Compensatory Increase of Transglutaminase 2 Is Responsible for Resistance to mTOR Inhibitor Treatment.
    Cao J; Huang W
    PLoS One; 2016; 11(2):e0149388. PubMed ID: 26872016
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Variation in proteomics and metabolomics of chicken hepatocytes exposed to medium with or without folic acid.
    Liu Y; Wu S; Sun W; Chen S; Yang X; Yang X
    J Cell Biochem; 2018 Jul; 119(7):6113-6124. PubMed ID: 29575257
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.