Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 35461070)

  • 1. The novel mechanism of Med12-mediated drug resistance in a TGFBR2-independent manner.
    Han Y; Dong Q; Liu T; Chen X; Yu C; Zhang Y
    Biochem Biophys Res Commun; 2022 Jun; 610():1-7. PubMed ID: 35461070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
    Jackson LM; Dhoonmoon A; Hale A; Dennis KA; Schleicher EM; Nicolae CM; Moldovan GL
    Nucleic Acids Res; 2021 Dec; 49(22):12855-12869. PubMed ID: 34871431
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The emerging role of mediator complex subunit 12 in tumorigenesis and response to chemotherapeutics.
    Zhang S; O'Regan R; Xu W
    Cancer; 2020 Mar; 126(5):939-948. PubMed ID: 31869450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.
    Huang S; Hölzel M; Knijnenburg T; Schlicker A; Roepman P; McDermott U; Garnett M; Grernrum W; Sun C; Prahallad A; Groenendijk FH; Mittempergher L; Nijkamp W; Neefjes J; Salazar R; Ten Dijke P; Uramoto H; Tanaka F; Beijersbergen RL; Wessels LF; Bernards R
    Cell; 2012 Nov; 151(5):937-50. PubMed ID: 23178117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NEAT1 repression by MED12 creates chemosensitivity in p53 wild-type breast cancer cells.
    Zhang S; Kim EJ; Huang J; Liu P; Donahue K; Wang Q; Wang Y; Mcilwain S; Xie L; Chen X; Li L; Xu W
    FEBS J; 2024 May; 291(9):1909-1924. PubMed ID: 38380720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TGF-β-SMAD-miR-520e axis regulates NSCLC metastasis through a TGFBR2-mediated negative-feedback loop.
    Kucuksayan H; Akgun S; Ozes ON; Alikanoglu AS; Yildiz M; Dal E; Akca H
    Carcinogenesis; 2019 Jul; 40(5):695-705. PubMed ID: 30475986
    [TBL] [Abstract][Full Text] [Related]  

  • 7.
    Siraj AK; Masoodi T; Bu R; Pratheeshkumar P; Al-Sanea N; Ashari LH; Abduljabbar A; Alhomoud S; Al-Dayel F; Alkuraya FS; Al-Kuraya KS
    Gut; 2018 Apr; 67(4):663-671. PubMed ID: 28183795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/β-Catenin Signaling Pathway.
    Al-Hendy A; Laknaur A; Diamond MP; Ismail N; Boyer TG; Halder SK
    Endocrinology; 2017 Mar; 158(3):592-603. PubMed ID: 27967206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs.
    Wang L; Zeng H; Wang Q; Zhao Z; Boyer TG; Bian X; Xu W
    Sci Adv; 2015 Oct; 1(9):e1500463. PubMed ID: 26601288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGFBR2‑dependent alterations of microRNA profiles in extracellular vesicles and parental colorectal cancer cells.
    Fricke F; Mussack V; Buschmann D; Hausser I; Pfaffl MW; Kopitz J; Gebert J
    Int J Oncol; 2019 Oct; 55(4):925-937. PubMed ID: 31432155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR.
    Luo XL; Deng CC; Su XD; Wang F; Chen Z; Wu XP; Liang SB; Liu JH; Fu LW
    Cancer Res; 2018 Jul; 78(13):3532-3543. PubMed ID: 29735544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance.
    Gao H; Bai P; Xiao L; Shen M; Yu Q; Lei Y; Huang W; Lin X; Zheng X; Wei T; Jiang Y; Ye F; Bu H
    J Biol Chem; 2020 Jul; 295(31):10726-10740. PubMed ID: 32532820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC.
    Xu M; Wang F; Li G; Wang X; Fang X; Jin H; Chen Z; Zhang J; Fu L
    Mol Cancer; 2019 May; 18(1):93. PubMed ID: 31072327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MiR-17-5p regulates cell proliferation and migration by targeting transforming growth factor-β receptor 2 in gastric cancer.
    Qu Y; Zhang H; Duan J; Liu R; Deng T; Bai M; Huang D; Li H; Ning T; Zhang L; Wang X; Ge S; Zhou L; Zhong B; Ying G; Ba Y
    Oncotarget; 2016 May; 7(22):33286-96. PubMed ID: 27120811
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A super-enhancer controls TGF- β signaling in pancreatic cancer through downregulation of TGFBR2.
    Zhu X; Zhang T; Zhang Y; Chen H; Shen J; Jin X; Wei J; Zhang E; Xiao M; Fan Y; Mao R; Zhou G
    Cell Signal; 2020 Feb; 66():109470. PubMed ID: 31730895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis.
    Meng X; Vander Ark A; Daft P; Woodford E; Wang J; Madaj Z; Li X
    Cancer Lett; 2018 Apr; 418():109-118. PubMed ID: 29337106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular mechanism of miR-153 inhibiting migration, invasion and epithelial-mesenchymal transition of breast cancer by regulating transforming growth factor beta (TGF-β) signaling pathway.
    Wang J; Liang S; Duan X
    J Cell Biochem; 2019 Jun; 120(6):9539-9546. PubMed ID: 30525231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of miR-135b as a novel regulator of TGFβ pathway in gastric cancer.
    Bai M; Wang P; Yang J; Zuo M; Ba Y
    J Physiol Biochem; 2020 Nov; 76(4):549-560. PubMed ID: 32737704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
    Park MJ; Shen H; Spaeth JM; Tolvanen JH; Failor C; Knudtson JF; McLaughlin J; Halder SK; Yang Q; Bulun SE; Al-Hendy A; Schenken RS; Aaltonen LA; Boyer TG
    J Biol Chem; 2018 Mar; 293(13):4870-4882. PubMed ID: 29440396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer.
    Busch S; Acar A; Magnusson Y; Gregersson P; Rydén L; Landberg G
    Oncogene; 2015 Jan; 34(1):27-38. PubMed ID: 24336330
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.