223 related articles for article (PubMed ID: 35462185)
1. The SARS-CoV-2 helicase as a target for antiviral therapy: Identification of potential small molecule inhibitors by in silico modelling.
Pitsillou E; Liang J; Hung A; Karagiannis TC
J Mol Graph Model; 2022 Jul; 114():108193. PubMed ID: 35462185
[TBL] [Abstract][Full Text] [Related]
2. In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity.
Mohammad TSH; Gupta Y; Reidl CT; Nicolaescu V; Gula H; Durvasula R; Kempaiah P; Becker DP
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982188
[TBL] [Abstract][Full Text] [Related]
3. SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts.
Shu T; Huang M; Wu D; Ren Y; Zhang X; Han Y; Mu J; Wang R; Qiu Y; Zhang DY; Zhou X
Virol Sin; 2020 Jun; 35(3):321-329. PubMed ID: 32500504
[TBL] [Abstract][Full Text] [Related]
4. Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach.
Romeo I; Ambrosio FA; Costa G; Corona A; Alkhatib M; Salpini R; Lemme S; Vergni D; Svicher V; Santoro MM; Tramontano E; Ceccherini-Silberstein F; Artese A; Alcaro S
Molecules; 2022 Nov; 27(21):. PubMed ID: 36364347
[TBL] [Abstract][Full Text] [Related]
5. SARS-CoV-2 nsp13 Restricts Episomal DNA Transcription without Affecting Chromosomal DNA.
Li A; Zhang B; Zhao K; Yin Z; Teng Y; Zhang L; Xu Z; Liang K; Cheng X; Xia Y
J Virol; 2023 Jul; 97(7):e0051223. PubMed ID: 37347173
[TBL] [Abstract][Full Text] [Related]
6. Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro.
Lu L; Peng Y; Yao H; Wang Y; Li J; Yang Y; Lin Z
Antiviral Res; 2022 Oct; 206():105389. PubMed ID: 35985407
[TBL] [Abstract][Full Text] [Related]
7. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
Zeng J; Weissmann F; Bertolin AP; Posse V; Canal B; Ulferts R; Wu M; Harvey R; Hussain S; Milligan JC; Roustan C; Borg A; McCoy L; Drury LS; Kjaer S; McCauley J; Howell M; Beale R; Diffley JFX
Biochem J; 2021 Jul; 478(13):2405-2423. PubMed ID: 34198322
[TBL] [Abstract][Full Text] [Related]
8. Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.
Ivanov KA; Thiel V; Dobbe JC; van der Meer Y; Snijder EJ; Ziebuhr J
J Virol; 2004 Jun; 78(11):5619-32. PubMed ID: 15140959
[TBL] [Abstract][Full Text] [Related]
9. Coronavirus helicases: attractive and unique targets of antiviral drug-development and therapeutic patents.
Spratt AN; Gallazzi F; Quinn TP; Lorson CL; Sönnerborg A; Singh K
Expert Opin Ther Pat; 2021 Apr; 31(4):339-350. PubMed ID: 33593200
[No Abstract] [Full Text] [Related]
10. A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
Grimes SL; Choi YJ; Banerjee A; Small G; Anderson-Daniels J; Gribble J; Pruijssers AJ; Agostini ML; Abu-Shmais A; Lu X; Darst SA; Campbell E; Denison MR
mBio; 2023 Aug; 14(4):e0106023. PubMed ID: 37338298
[TBL] [Abstract][Full Text] [Related]
11. Potential phytochemical inhibitors of SARS-CoV-2 helicase Nsp13: a molecular docking and dynamic simulation study.
Vivek-Ananth RP; Krishnaswamy S; Samal A
Mol Divers; 2022 Feb; 26(1):429-442. PubMed ID: 34117992
[TBL] [Abstract][Full Text] [Related]
12.
Gurung AB
Gene Rep; 2020 Dec; 21():100860. PubMed ID: 32875166
[TBL] [Abstract][Full Text] [Related]
13. The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
Zheng T; Shen B; Bai Y; Li E; Zhang X; Hu Y; Gao T; Dong Q; Zhu L; Jin R; Shi H; Liu H; Gao Y; Liu X; Cao C
J Virol; 2024 Apr; 98(4):e0156523. PubMed ID: 38445884
[TBL] [Abstract][Full Text] [Related]
14. Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase.
Freidel MR; Armen RS
PLoS One; 2021; 16(2):e0246181. PubMed ID: 33596235
[TBL] [Abstract][Full Text] [Related]
15. Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase.
White MA; Lin W; Cheng X
J Phys Chem Lett; 2020 Nov; 11(21):9144-9151. PubMed ID: 33052685
[TBL] [Abstract][Full Text] [Related]
16. Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase.
Abidi SH; Almansour NM; Amerzhanov D; Allemailem KS; Rafaqat W; Ibrahim MAA; la Fleur P; Lukac M; Ali S
Sci Rep; 2021 May; 11(1):10290. PubMed ID: 33986405
[TBL] [Abstract][Full Text] [Related]
17. Structure-Based Virtual Screening Identifies Multiple Stable Binding Sites at the RecA Domains of SARS-CoV-2 Helicase Enzyme.
Ahmad S; Waheed Y; Ismail S; Bhatti S; Abbasi SW; Muhammad K
Molecules; 2021 Mar; 26(5):. PubMed ID: 33800013
[TBL] [Abstract][Full Text] [Related]
18. Generalized open-source workflows for atomistic molecular dynamics simulations of viral helicases.
Raubenolt B; Blankenberg D
Gigascience; 2024 Jan; 13():. PubMed ID: 38869150
[TBL] [Abstract][Full Text] [Related]
19. Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target.
Keum YS; Jeong YJ
Biochem Pharmacol; 2012 Nov; 84(10):1351-8. PubMed ID: 22935448
[TBL] [Abstract][Full Text] [Related]
20. The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.
Tanner JA; Watt RM; Chai YB; Lu LY; Lin MC; Peiris JS; Poon LL; Kung HF; Huang JD
J Biol Chem; 2003 Oct; 278(41):39578-82. PubMed ID: 12917423
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]