227 related articles for article (PubMed ID: 35463958)
1. Autopromotion of K-Ras4B Feedback Activation Through an SOS-Mediated Long-Range Allosteric Effect.
He X; Du K; Wang Y; Fan J; Li M; Ni D; Lu S; Bian X; Liu Y
Front Mol Biosci; 2022; 9():860962. PubMed ID: 35463958
[TBL] [Abstract][Full Text] [Related]
2. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.
Moghadamchargari Z; Shirzadeh M; Liu C; Schrecke S; Packianathan C; Russell DH; Zhao M; Laganowsky A
Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723061
[TBL] [Abstract][Full Text] [Related]
3. Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.
Li X; Dai J; Ni D; He X; Zhang H; Zhang J; Fu Q; Liu Y; Lu S
Int J Biol Macromol; 2020 Feb; 144():643-655. PubMed ID: 31816384
[TBL] [Abstract][Full Text] [Related]
4. Biophysical Characterization of RAS-SOS Complexes by Native Mass Spectrometry.
Yun S; Scott E; Laganowsky A
Methods Mol Biol; 2024; 2797():177-193. PubMed ID: 38570460
[TBL] [Abstract][Full Text] [Related]
5. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
Lu S; Banerjee A; Jang H; Zhang J; Gaponenko V; Nussinov R
J Biol Chem; 2015 Nov; 290(48):28887-900. PubMed ID: 26453300
[TBL] [Abstract][Full Text] [Related]
6. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
Vo U; Vajpai N; Flavell L; Bobby R; Breeze AL; Embrey KJ; Golovanov AP
J Biol Chem; 2016 Jan; 291(4):1703-1718. PubMed ID: 26565026
[TBL] [Abstract][Full Text] [Related]
7. The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.
Lu S; Jang H; Nussinov R; Zhang J
Sci Rep; 2016 Feb; 6():21949. PubMed ID: 26902995
[TBL] [Abstract][Full Text] [Related]
8. Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.
Liao TJ; Jang H; Fushman D; Nussinov R
Biophys J; 2018 Aug; 115(4):629-641. PubMed ID: 30097175
[TBL] [Abstract][Full Text] [Related]
9. A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman TS; Sondermann H; Friedland GD; Kortemme T; Bar-Sagi D; Marqusee S; Kuriyan J
Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16692-7. PubMed ID: 17075039
[TBL] [Abstract][Full Text] [Related]
10. The higher level of complexity of K-Ras4B activation at the membrane.
Jang H; Banerjee A; Chavan TS; Lu S; Zhang J; Gaponenko V; Nussinov R
FASEB J; 2016 Apr; 30(4):1643-55. PubMed ID: 26718888
[TBL] [Abstract][Full Text] [Related]
11. Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins.
Wang Y; Ji D; Lei C; Chen Y; Qiu Y; Li X; Li M; Ni D; Pu J; Zhang J; Fu Q; Liu Y; Lu S
Comput Struct Biotechnol J; 2021; 19():1184-1199. PubMed ID: 33680360
[TBL] [Abstract][Full Text] [Related]
12. Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling.
Dudas B; Merzel F; Jang H; Nussinov R; Perahia D; Balog E
Front Mol Biosci; 2020; 7():145. PubMed ID: 32754617
[TBL] [Abstract][Full Text] [Related]
13. The Interdependent Activation of Son-of-Sevenless and Ras.
Bandaru P; Kondo Y; Kuriyan J
Cold Spring Harb Perspect Med; 2019 Feb; 9(2):. PubMed ID: 29610148
[TBL] [Abstract][Full Text] [Related]
14. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.
Margarit SM; Sondermann H; Hall BE; Nagar B; Hoelz A; Pirruccello M; Bar-Sagi D; Kuriyan J
Cell; 2003 Mar; 112(5):685-95. PubMed ID: 12628188
[TBL] [Abstract][Full Text] [Related]
15. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1.
Freedman TS; Sondermann H; Kuchment O; Friedland GD; Kortemme T; Kuriyan J
Structure; 2009 Jan; 17(1):41-53. PubMed ID: 19141281
[TBL] [Abstract][Full Text] [Related]
16. Studying early structural changes in SOS1 mediated KRAS activation mechanism.
Bhadhadhara K; Jani V; Koulgi S; Sonavane U; Joshi R
Curr Res Struct Biol; 2024; 7():100115. PubMed ID: 38188543
[TBL] [Abstract][Full Text] [Related]
17. Structural analysis of autoinhibition in the Ras activator Son of sevenless.
Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J
Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences.
Chakrabarti M; Jang H; Nussinov R
J Phys Chem B; 2016 Feb; 120(4):667-79. PubMed ID: 26761128
[TBL] [Abstract][Full Text] [Related]
19. New insights into the mechanisms of SOS activation.
Quilliam LA
Sci STKE; 2007 Nov; 2007(414):pe67. PubMed ID: 18042941
[TBL] [Abstract][Full Text] [Related]
20. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
Grudzien P; Jang H; Leschinsky N; Nussinov R; Gaponenko V
J Mol Biol; 2022 Sep; 434(17):167695. PubMed ID: 35752212
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]