281 related articles for article (PubMed ID: 35468899)
1. Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes.
Chegão A; Guarda M; Alexandre BM; Shvachiy L; Temido-Ferreira M; Marques-Morgado I; Fernandes Gomes B; Matthiesen R; Lopes LV; Florindo PR; Gomes RA; Gomes-Alves P; Coelho JE; Outeiro TF; Vicente Miranda H
NPJ Parkinsons Dis; 2022 Apr; 8(1):51. PubMed ID: 35468899
[TBL] [Abstract][Full Text] [Related]
2. Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein.
Vicente Miranda H; Chegão A; Oliveira MS; Fernandes Gomes B; Enguita FJ; Outeiro TF
FASEB J; 2020 May; 34(5):6718-6728. PubMed ID: 32259355
[TBL] [Abstract][Full Text] [Related]
3. Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.
Subramaniam SR; Vergnes L; Franich NR; Reue K; Chesselet MF
Neurobiol Dis; 2014 Oct; 70():204-13. PubMed ID: 25016198
[TBL] [Abstract][Full Text] [Related]
4. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
Sharma N; Rao SP; Kalivendi SV
Free Radic Biol Med; 2019 May; 135():28-37. PubMed ID: 30796974
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector-Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain.
Svarcbahs R; Julku UH; Myöhänen TT
J Neurosci; 2016 Dec; 36(49):12485-12497. PubMed ID: 27927963
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson's Disease.
Bermúdez ML; Seroogy KB; Genter MB
Neuroscience; 2019 Jul; 411():270-278. PubMed ID: 31125602
[TBL] [Abstract][Full Text] [Related]
7. Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.
Bermúdez ML; Skelton MR; Genter MB
Mol Genet Metab; 2018 Nov; 125(3):305-313. PubMed ID: 30146452
[TBL] [Abstract][Full Text] [Related]
8. Overexpression of Wild-Type Human Alpha-Synuclein Causes Metabolism Abnormalities in Thy1-aSYN Transgenic Mice.
Cuvelier E; Méquinion M; Leghay C; Sibran W; Stievenard A; Sarchione A; Bonte MA; Vanbesien-Mailliot C; Viltart O; Saitoski K; Caron E; Labarthe A; Comptdaer T; Semaille P; Carrié H; Mutez E; Gressier B; Destée A; Chartier-Harlin MC; Belarbi K
Front Mol Neurosci; 2018; 11():321. PubMed ID: 30333721
[TBL] [Abstract][Full Text] [Related]
9. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons.
Cabeza-Arvelaiz Y; Fleming SM; Richter F; Masliah E; Chesselet MF; Schiestl RH
Mol Neurodegener; 2011 Dec; 6():83. PubMed ID: 22165993
[TBL] [Abstract][Full Text] [Related]
10. The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease.
Price DL; Koike MA; Khan A; Wrasidlo W; Rockenstein E; Masliah E; Bonhaus D
Sci Rep; 2018 Nov; 8(1):16165. PubMed ID: 30385782
[TBL] [Abstract][Full Text] [Related]
11. Membrane binding, internalization, and sorting of alpha-synuclein in the cell.
Masaracchia C; Hnida M; Gerhardt E; Lopes da Fonseca T; Villar-Pique A; Branco T; Stahlberg MA; Dean C; Fernández CO; Milosevic I; Outeiro TF
Acta Neuropathol Commun; 2018 Aug; 6(1):79. PubMed ID: 30107856
[TBL] [Abstract][Full Text] [Related]
12. Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease.
Magen I; Torres ER; Dinh D; Chung A; Masliah E; Chesselet MF
J Parkinsons Dis; 2015; 5(3):669-680. PubMed ID: 25588356
[TBL] [Abstract][Full Text] [Related]
13. Nurr1 repression mediates cardinal features of Parkinson's disease in α-synuclein transgenic mice.
Argyrofthalmidou M; Spathis AD; Maniati M; Poula A; Katsianou MA; Sotiriou E; Manousaki M; Perier C; Papapanagiotou I; Papadopoulou-Daifoti Z; Pitychoutis PM; Alexakos P; Vila M; Stefanis L; Vassilatis DK
Hum Mol Genet; 2021 Jul; 30(16):1469-1483. PubMed ID: 33902111
[TBL] [Abstract][Full Text] [Related]
14. Protein trapping leads to altered synaptic proteostasis in synucleinopathies.
Santos PI; Outeiro TF
FEBS J; 2020 Dec; 287(24):5294-5303. PubMed ID: 32400966
[TBL] [Abstract][Full Text] [Related]
15. Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation.
Wang L; Magen I; Yuan PQ; Subramaniam SR; Richter F; Chesselet MF; Taché Y
Neurogastroenterol Motil; 2012 Sep; 24(9):e425-36. PubMed ID: 22779732
[TBL] [Abstract][Full Text] [Related]
16. Microvascular blood-brain barrier alterations in isolated brain capillaries of mice over-expressing alpha-synuclein (Thy1-aSyn line 61).
Lau K; Porschen LT; Richter F; Gericke B
Neurobiol Dis; 2023 Oct; 187():106298. PubMed ID: 37716515
[TBL] [Abstract][Full Text] [Related]
17. Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.
Seebauer L; Schneider Y; Drobny A; Plötz S; Koudelka T; Tholey A; Prots I; Winner B; Zunke F; Winkler J; Xiang W
Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163733
[TBL] [Abstract][Full Text] [Related]
18. α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.
Delaidelli A; Richner M; Jiang L; van der Laan A; Bergholdt Jul Christiansen I; Ferreira N; Nyengaard JR; Vægter CB; Jensen PH; Mackenzie IR; Sorensen PH; Jan A
Acta Neuropathol Commun; 2021 Jun; 9(1):105. PubMed ID: 34092244
[TBL] [Abstract][Full Text] [Related]
19. Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies.
Brás IC; Outeiro TF
Cells; 2021 Feb; 10(2):. PubMed ID: 33673034
[TBL] [Abstract][Full Text] [Related]
20. Could α-Synuclein Modulation of Insulin and Dopamine Identify a Novel Link Between Parkinson's Disease and Diabetes as Well as Potential Therapies?
Vidal-Martinez G; Yang B; Vargas-Medrano J; Perez RG
Front Mol Neurosci; 2018; 11():465. PubMed ID: 30622456
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]