These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 35469978)

  • 1. Efficient spontaneous site-selective cysteine-mediated toxin attachment within a structural loop of antibodies.
    Stadlmayr G; Stracke F; Stadlbauer K; Rybka J; Dickgiesser S; Rasche N; Becker S; Toleikis L; Rüker F; Knopp GW
    Biochim Biophys Acta Gen Subj; 2022 Jul; 1866(7):130155. PubMed ID: 35469978
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs.
    Behrens CR; Ha EH; Chinn LL; Bowers S; Probst G; Fitch-Bruhns M; Monteon J; Valdiosera A; Bermudez A; Liao-Chan S; Wong T; Melnick J; Theunissen JW; Flory MR; Houser D; Venstrom K; Levashova Z; Sauer P; Migone TS; van der Horst EH; Halcomb RL; Jackson DY
    Mol Pharm; 2015 Nov; 12(11):3986-98. PubMed ID: 26393951
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Cysteine Insertion.
    Dimasi N; Fleming R; Zhong H; Bezabeh B; Kinneer K; Christie RJ; Fazenbaker C; Wu H; Gao C
    Mol Pharm; 2017 May; 14(5):1501-1516. PubMed ID: 28245132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro and in vivo evaluation of cysteine and site specific conjugated herceptin antibody-drug conjugates.
    Jackson D; Atkinson J; Guevara CI; Zhang C; Kery V; Moon SJ; Virata C; Yang P; Lowe C; Pinkstaff J; Cho H; Knudsen N; Manibusan A; Tian F; Sun Y; Lu Y; Sellers A; Jia XC; Joseph I; Anand B; Morrison K; Pereira DS; Stover D
    PLoS One; 2014; 9(1):e83865. PubMed ID: 24454709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and Validation of Linkers for Site-Specific Preparation of Antibody-Drug Conjugates Carrying Multiple Drug Copies Per Cysteine Conjugation Site.
    Kumar A; Mao S; Dimasi N; Gao C
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32961794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.
    Beerli RR; Hell T; Merkel AS; Grawunder U
    PLoS One; 2015; 10(7):e0131177. PubMed ID: 26132162
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Advances in the Development of Site-Specific Antibody-Drug Conjugation.
    Zhou Q; Kim J
    Anticancer Agents Med Chem; 2015; 15(7):828-36. PubMed ID: 25731178
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Orthogonal Cysteine Protection Enables Homogeneous Multi-Drug Antibody-Drug Conjugates.
    Levengood MR; Zhang X; Hunter JH; Emmerton KK; Miyamoto JB; Lewis TS; Senter PD
    Angew Chem Int Ed Engl; 2017 Jan; 56(3):733-737. PubMed ID: 27966822
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer.
    White JB; Fleming R; Masterson L; Ruddle BT; Zhong H; Fazenbaker C; Strout P; Rosenthal K; Reed M; Muniz-Medina V; Howard P; Dixit R; Wu H; Hinrichs MJ; Gao C; Dimasi N
    MAbs; 2019 Apr; 11(3):500-515. PubMed ID: 30835621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent Chemical Approaches for Site-Specific Conjugation of Native Antibodies: Technologies toward Next-Generation Antibody-Drug Conjugates.
    Yamada K; Ito Y
    Chembiochem; 2019 Nov; 20(21):2729-2737. PubMed ID: 30973187
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Genetically Encoded Photocaged Cysteine for Facile Site-Specific Introduction of Conjugation-Ready Thiol Residues in Antibodies.
    Osgood AO; Roy SJS; Koo D; Gu R; Chatterjee A
    Bioconjug Chem; 2024 Apr; 35(4):457-464. PubMed ID: 38548654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid.
    Zhang L; Wang Z; Wang Z; Luo F; Guan M; Xu M; Li Y; Zhang Y; Wang Z; Wang W
    Bioconjug Chem; 2021 Jun; 32(6):1094-1104. PubMed ID: 34013721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Practical approaches for overcoming challenges in heightened characterization of antibody-drug conjugates with new methodologies and ultrahigh-resolution mass spectrometry.
    Friese OV; Smith JN; Brown PW; Rouse JC
    MAbs; 2018 Apr; 10(3):335-345. PubMed ID: 29393747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineered cysteine antibodies: an improved antibody-drug conjugate platform with a novel mechanism of drug-linker stability.
    Sussman D; Westendorf L; Meyer DW; Leiske CI; Anderson M; Okeley NM; Alley SC; Lyon R; Sanderson RJ; Carter PJ; Benjamin DR
    Protein Eng Des Sel; 2018 Feb; 31(2):47-54. PubMed ID: 29370435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conjugations to Endogenous Cysteine Residues.
    Nadkarni DV
    Methods Mol Biol; 2020; 2078():37-49. PubMed ID: 31643048
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography.
    Birdsall RE; Shion H; Kotch FW; Xu A; Porter TJ; Chen W
    MAbs; 2015; 7(6):1036-44. PubMed ID: 26305867
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Recent Developments of ADCs with the Tubulysins as the Payloads.
    Xiangrong X; Yao L; Yao A
    Mini Rev Med Chem; 2023; 23(18):1797-1805. PubMed ID: 36825713
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of Drug Conjugation and Loading on Target Antigen Binding and Cytotoxicity in Cysteine Antibody-Drug Conjugates.
    Nadkarni DV; Lee J; Jiang Q; Patel V; Sriskanda V; Dutta K; Meyer DM
    Mol Pharm; 2021 Mar; 18(3):889-897. PubMed ID: 33470823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics.
    Thompson P; Fleming R; Bezabeh B; Huang F; Mao S; Chen C; Harper J; Zhong H; Gao X; Yu XQ; Hinrichs MJ; Reed M; Kamal A; Strout P; Cho S; Woods R; Hollingsworth RE; Dixit R; Wu H; Gao C; Dimasi N
    J Control Release; 2016 Aug; 236():100-16. PubMed ID: 27327768
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.
    Li X; Patterson JT; Sarkar M; Pedzisa L; Kodadek T; Roush WR; Rader C
    Bioconjug Chem; 2015 Nov; 26(11):2243-8. PubMed ID: 26161903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.