233 related articles for article (PubMed ID: 35483450)
1. Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
Nagy ZA; Héja D; Bencze D; Kiss B; Boros E; Szakács D; Fodor K; Wilmanns M; Kocsis A; Dobó J; Gál P; Harmat V; Pál G
J Biol Chem; 2022 Jun; 298(6):101985. PubMed ID: 35483450
[TBL] [Abstract][Full Text] [Related]
2. The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin.
Gaboriaud C; Gupta RK; Martin L; Lacroix M; Serre L; Teillet F; Arlaud GJ; Rossi V; Thielens NM
PLoS One; 2013; 8(7):e67962. PubMed ID: 23861840
[TBL] [Abstract][Full Text] [Related]
3. Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum.
Nagy ZA; Szakács D; Boros E; Héja D; Vígh E; Sándor N; Józsi M; Oroszlán G; Dobó J; Gál P; Pál G
PLoS Pathog; 2019 Dec; 15(12):e1008232. PubMed ID: 31860690
[TBL] [Abstract][Full Text] [Related]
4. Dissociation and re-association studies on the interaction domains of mannan-binding lectin (MBL)-associated serine proteases, MASP-1 and MASP-2, provide evidence for heterodimer formation.
Paréj K; Hermann A; Donáth N; Závodszky P; Gál P; Dobó J
Mol Immunol; 2014 May; 59(1):1-9. PubMed ID: 24424083
[TBL] [Abstract][Full Text] [Related]
5. Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.
Takahashi M; Iwaki D; Kanno K; Ishida Y; Xiong J; Matsushita M; Endo Y; Miura S; Ishii N; Sugamura K; Fujita T
J Immunol; 2008 May; 180(9):6132-8. PubMed ID: 18424734
[TBL] [Abstract][Full Text] [Related]
6. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
Héja D; Harmat V; Fodor K; Wilmanns M; Dobó J; Kékesi KA; Závodszky P; Gál P; Pál G
J Biol Chem; 2012 Jun; 287(24):20290-300. PubMed ID: 22511776
[TBL] [Abstract][Full Text] [Related]
7. Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.
Takahashi M; Ishida Y; Iwaki D; Kanno K; Suzuki T; Endo Y; Homma Y; Fujita T
J Exp Med; 2010 Jan; 207(1):29-37. PubMed ID: 20038603
[TBL] [Abstract][Full Text] [Related]
8. A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations.
Gál P; Harmat V; Kocsis A; Bián T; Barna L; Ambrus G; Végh B; Balczer J; Sim RB; Náray-Szabó G; Závodszky P
J Biol Chem; 2005 Sep; 280(39):33435-44. PubMed ID: 16040602
[TBL] [Abstract][Full Text] [Related]
9. Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation.
Kocsis A; Kékesi KA; Szász R; Végh BM; Balczer J; Dobó J; Závodszky P; Gál P; Pál G
J Immunol; 2010 Oct; 185(7):4169-78. PubMed ID: 20817870
[TBL] [Abstract][Full Text] [Related]
10. Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway.
Megyeri M; Harmat V; Major B; Végh Á; Balczer J; Héja D; Szilágyi K; Datz D; Pál G; Závodszky P; Gál P; Dobó J
J Biol Chem; 2013 Mar; 288(13):8922-34. PubMed ID: 23386610
[TBL] [Abstract][Full Text] [Related]
11. Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region.
Dobó J; Harmat V; Sebestyén E; Beinrohr L; Závodszky P; Gál P
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Sep; 64(Pt 9):781-4. PubMed ID: 18765903
[TBL] [Abstract][Full Text] [Related]
12. The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions.
Harmat V; Gál P; Kardos J; Szilágyi K; Ambrus G; Végh B; Náray-Szabó G; Závodszky P
J Mol Biol; 2004 Oct; 342(5):1533-46. PubMed ID: 15364579
[TBL] [Abstract][Full Text] [Related]
13. Structural insights into the initiating complex of the lectin pathway of complement activation.
Kjaer TR; Le le TM; Pedersen JS; Sander B; Golas MM; Jensenius JC; Andersen GR; Thiel S
Structure; 2015 Feb; 23(2):342-51. PubMed ID: 25579818
[TBL] [Abstract][Full Text] [Related]
14. Structural and functional overview of the lectin complement pathway: its molecular basis and physiological implication.
Matsushita M; Endo Y; Fujita T
Arch Immunol Ther Exp (Warsz); 2013 Aug; 61(4):273-83. PubMed ID: 23563865
[TBL] [Abstract][Full Text] [Related]
15. Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Nan R; Furze CM; Wright DW; Gor J; Wallis R; Perkins SJ
Structure; 2017 Feb; 25(2):364-375. PubMed ID: 28111019
[TBL] [Abstract][Full Text] [Related]
16. Toward a structure-based comprehension of the lectin pathway of complement.
Kjaer TR; Thiel S; Andersen GR
Mol Immunol; 2013 Dec; 56(4):413-22. PubMed ID: 23911397
[TBL] [Abstract][Full Text] [Related]
17. Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.
Degn SE; Jensen L; Olszowski T; Jensenius JC; Thiel S
J Immunol; 2013 Aug; 191(3):1334-45. PubMed ID: 23785123
[TBL] [Abstract][Full Text] [Related]
18. The role of ecotin dimerization in protease inhibition.
Eggers CT; Wang SX; Fletterick RJ; Craik CS
J Mol Biol; 2001 May; 308(5):975-91. PubMed ID: 11352586
[TBL] [Abstract][Full Text] [Related]
19. The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.
Dobó J; Pál G; Cervenak L; Gál P
Immunol Rev; 2016 Nov; 274(1):98-111. PubMed ID: 27782318
[TBL] [Abstract][Full Text] [Related]
20. A journey through the lectin pathway of complement-MBL and beyond.
Garred P; Genster N; Pilely K; Bayarri-Olmos R; Rosbjerg A; Ma YJ; Skjoedt MO
Immunol Rev; 2016 Nov; 274(1):74-97. PubMed ID: 27782323
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
