BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 35483669)

  • 1. Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example.
    Nyffeler J; Willis C; Harris FR; Taylor LW; Judson R; Everett LJ; Harrill JA
    Toxicol Appl Pharmacol; 2022 Jun; 444():116032. PubMed ID: 35483669
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments.
    Nyffeler J; Willis C; Harris FR; Foster MJ; Chambers B; Culbreth M; Brockway RE; Davidson-Fritz S; Dawson D; Shah I; Friedman KP; Chang D; Everett LJ; Wambaugh JF; Patlewicz G; Harrill JA
    Toxicol Appl Pharmacol; 2023 Jun; 468():116513. PubMed ID: 37044265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening.
    Culbreth M; Nyffeler J; Willis C; Harrill JA
    Front Toxicol; 2021; 3():803987. PubMed ID: 35295155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling.
    Nyffeler J; Willis C; Lougee R; Richard A; Paul-Friedman K; Harrill JA
    Toxicol Appl Pharmacol; 2020 Jan; 389():114876. PubMed ID: 31899216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-Throughput Transcriptomics Platform for Screening Environmental Chemicals.
    Harrill JA; Everett LJ; Haggard DE; Sheffield T; Bundy JL; Willis CM; Thomas RS; Shah I; Judson RS
    Toxicol Sci; 2021 Apr; 181(1):68-89. PubMed ID: 33538836
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigating open access new approach methods (NAM) to assess biological points of departure: A case study with 4 neurotoxic pesticides.
    Silva MH
    Curr Res Toxicol; 2024; 6():100156. PubMed ID: 38404712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions.
    Harrill J; Shah I; Setzer RW; Haggard D; Auerbach S; Judson R; Thomas RS
    Curr Opin Toxicol; 2019; 15():64-75. PubMed ID: 31501805
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression.
    Centritto F; Paroni G; Bolis M; Garattini SK; Kurosaki M; Barzago MM; Zanetti A; Fisher JN; Scott MF; Pattini L; Lupi M; Ubezio P; Piccotti F; Zambelli A; Rizzo P; Gianni' M; Fratelli M; Terao M; Garattini E
    EMBO Mol Med; 2015 Jul; 7(7):950-72. PubMed ID: 25888236
    [TBL] [Abstract][Full Text] [Related]  

  • 9. All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation.
    Yang QJ; Zhou LY; Mu YQ; Zhou QX; Luo JY; Cheng L; Deng ZL; He TC; Haydon RC; He BC
    Int J Oncol; 2012 Jul; 41(1):153-60. PubMed ID: 22485251
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect pathway of retinoic acid through regulation of retinoic acid receptor alpha in gastric cancer cells.
    Liu S; Wu Q; Chen ZM; Su WJ
    World J Gastroenterol; 2001 Oct; 7(5):662-6. PubMed ID: 11819850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells.
    Gianní M; Li Calzi M; Terao M; Guiso G; Caccia S; Barbui T; Rambaldi A; Garattini E
    Blood; 1996 Feb; 87(4):1520-31. PubMed ID: 8608243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced potency of 9-cis versus all-trans-retinoic acid to induce the differentiation of human neuroblastoma cells.
    Han G; Chang B; Connor MJ; Sidell N
    Differentiation; 1995 Jul; 59(1):61-9. PubMed ID: 7589896
    [TBL] [Abstract][Full Text] [Related]  

  • 13. All-trans retinoic acid induces COX-2 and prostaglandin E2 synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2.
    Alique M; Herrero JF; Lucio-Cazana FJ
    J Neuroinflammation; 2007 Jan; 4():1. PubMed ID: 17204142
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype.
    Higuchi E; Chandraratna RA; Hong WK; Lotan R
    Oncogene; 2003 Jul; 22(30):4627-35. PubMed ID: 12879006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploring the effects of experimental parameters and data modeling approaches on in vitro transcriptomic point-of-departure estimates.
    Harrill JA; Everett LJ; Haggard DE; Bundy JL; Willis CM; Shah I; Friedman KP; Basili D; Middleton A; Judson RS
    Toxicology; 2024 Jan; 501():153694. PubMed ID: 38043774
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational model for fetal skeletal defects potentially linked to disruption of retinoic acid signaling.
    Pierro JD; Ahir BK; Baker NC; Kleinstreuer NC; Xia M; Knudsen TB
    Front Pharmacol; 2022; 13():971296. PubMed ID: 36172177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells.
    Nakajima H; Kizaki M; Sonoda A; Mori S; Harigaya K; Ikeda Y
    Blood; 1994 Dec; 84(12):4107-15. PubMed ID: 7994028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay.
    Willis C; Nyffeler J; Harrill J
    SLAS Discov; 2020 Aug; 25(7):755-769. PubMed ID: 32546035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Towards replacement of animal tests with in vitro assays: a gene expression biomarker predicts in vitro and in vivo estrogen receptor activity.
    Corton JC; Liu J; Kleinstreuer N; Gwinn MR; Ryan N
    Chem Biol Interact; 2022 Aug; 363():109995. PubMed ID: 35697134
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans-retinoic acid in primary rat hepatocytes.
    Dvorák Z; Vrzal R; Ulrichová J; Macejová D; Ondková S; Brtko J
    Mol Cell Endocrinol; 2007 Mar; 267(1-2):89-96. PubMed ID: 17291686
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.