BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 35486339)

  • 1. Impact of JAK Inhibitors in Pediatric Patients with STAT1 Gain of Function (GOF) Mutations-10 Children and Review of the Literature.
    Deyà-Martínez A; Rivière JG; Roxo-Junior P; Ramakers J; Bloomfield M; Guisado Hernandez P; Blanco Lobo P; Abu Jamra SR; Esteve-Sole A; Kanderova V; García-García A; Lopez-Corbeto M; Martinez Pomar N; Martín-Nalda A; Alsina L; Neth O; Olbrich P
    J Clin Immunol; 2022 Jul; 42(5):1071-1082. PubMed ID: 35486339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JAK inhibitor treatment for inborn errors of JAK/STAT signaling: An ESID/EBMT-IEWP retrospective study.
    Fischer M; Olbrich P; Hadjadj J; Aumann V; Bakhtiar S; Barlogis V; von Bismarck P; Bloomfield M; Booth C; Buddingh EP; Cagdas D; Castelle M; Chan AY; Chandrakasan S; Chetty K; Cougoul P; Crickx E; Dara J; Deyà-Martínez A; Farmand S; Formankova R; Gennery AR; Gonzalez-Granado LI; Hagin D; Hanitsch LG; Hanzlikovà J; Hauck F; Ivorra-Cortés J; Kisand K; Kiykim A; Körholz J; Leahy TR; van Montfrans J; Nademi Z; Nelken B; Parikh S; Plado S; Ramakers J; Redlich A; Rieux-Laucat F; Rivière JG; Rodina Y; Júnior PR; Salou S; Schuetz C; Shcherbina A; Slatter MA; Touzot F; Unal E; Lankester AC; Burns S; Seppänen MRJ; Neth O; Albert MH; Ehl S; Neven B; Speckmann C
    J Allergy Clin Immunol; 2024 Jan; 153(1):275-286.e18. PubMed ID: 37935260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Patients with STAT1 Gain-of-function Mutations Display Increased Apoptosis which is Reversed by the JAK Inhibitor Ruxolitinib.
    Dotta L; Todaro F; Baronio M; Giacomelli M; Pinelli M; Giambarda M; Brognoli B; Greco S; Rota F; Cortesi M; Soresina A; Moratto D; Tomasi C; Ferraro RM; Giliani S; Badolato R
    J Clin Immunol; 2024 Apr; 44(4):85. PubMed ID: 38578354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation.
    Kayaoglu B; Kasap N; Yilmaz NS; Charbonnier LM; Geckin B; Akcay A; Eltan SB; Ozturk G; Ozen A; Karakoc-Aydiner E; Chatila TA; Gursel M; Baris S
    J Clin Immunol; 2021 May; 41(4):769-779. PubMed ID: 33475942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recapitulating primary immunodeficiencies with expanded potential stem cells: Proof of concept with STAT1 gain of function.
    Liu X; Chan VSF; Smith KGC; Ming C; Or CS; Tsui FTW; Gao B; Cook MC; Liu P; Lau CS; Li PH
    J Allergy Clin Immunol; 2024 Apr; 153(4):1125-1139. PubMed ID: 38072195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation.
    Bloomfield M; Kanderová V; Paračková Z; Vrabcová P; Svatoň M; Froňková E; Fejtková M; Zachová R; Rataj M; Zentsová I; Milota T; Klocperk A; Kalina T; Šedivá A
    J Clin Immunol; 2018 Jul; 38(5):589-601. PubMed ID: 29934865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical Relevance of Gain- and Loss-of-Function Germline Mutations in STAT1: A Systematic Review.
    Zhang W; Chen X; Gao G; Xing S; Zhou L; Tang X; Zhao X; An Y
    Front Immunol; 2021; 12():654406. PubMed ID: 33777053
    [No Abstract]   [Full Text] [Related]  

  • 8. Severe Early-Onset Combined Immunodeficiency due to Heterozygous Gain-of-Function Mutations in STAT1.
    Baris S; Alroqi F; Kiykim A; Karakoc-Aydiner E; Ogulur I; Ozen A; Charbonnier LM; Bakır M; Boztug K; Chatila TA; Barlan IB
    J Clin Immunol; 2016 Oct; 36(7):641-8. PubMed ID: 27379765
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.
    Vargas-Hernández A; Mace EM; Zimmerman O; Zerbe CS; Freeman AF; Rosenzweig S; Leiding JW; Torgerson T; Altman MC; Schussler E; Cunningham-Rundles C; Chinn IK; Carisey AF; Hanson IC; Rider NL; Holland SM; Orange JS; Forbes LR
    J Allergy Clin Immunol; 2018 Jun; 141(6):2142-2155.e5. PubMed ID: 29111217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations.
    Leiding JW; Okada S; Hagin D; Abinun M; Shcherbina A; Balashov DN; Kim VHD; Ovadia A; Guthery SL; Pulsipher M; Lilic D; Devlin LA; Christie S; Depner M; Fuchs S; van Royen-Kerkhof A; Lindemans C; Petrovic A; Sullivan KE; Bunin N; Kilic SS; Arpaci F; Calle-Martin O; Martinez-Martinez L; Aldave JC; Kobayashi M; Ohkawa T; Imai K; Iguchi A; Roifman CM; Gennery AR; Slatter M; Ochs HD; Morio T; Torgerson TR;
    J Allergy Clin Immunol; 2018 Feb; 141(2):704-717.e5. PubMed ID: 28601685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ex vivo effect of JAK inhibition on JAK-STAT1 pathway hyperactivation in patients with dominant-negative STAT3 mutations.
    Lobo PB; Guisado-Hernández P; Villaoslada I; de Felipe B; Carreras C; Rodriguez H; Carazo-Gallego B; Méndez-Echevarria A; Lucena JM; Aljaro PO; Castro MJ; Noguera-Uclés JF; Milner JD; McCann K; Zimmerman O; Freeman AF; Lionakis MS; Holland SM; Neth O; Olbrich P
    J Clin Immunol; 2022 Aug; 42(6):1193-1204. PubMed ID: 35507130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neutrophils in STAT1 Gain-Of-Function Have a Pro-inflammatory Signature Which Is Not Rescued by JAK Inhibition.
    Parackova Z; Vrabcova P; Zentsova I; Sediva A; Bloomfield M
    J Clin Immunol; 2023 Oct; 43(7):1640-1659. PubMed ID: 37358695
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chronic demodicosis in patients with immune dysregulation: An unexpected infectious manifestation of Signal transducer and activator of transcription (STAT)1 gain-of-function.
    Shamriz O; Lev A; Simon AJ; Barel O; Javasky E; Matza-Porges S; Shaulov A; Davidovics Z; Toker O; Somech R; Zlotogorski A; Molho-Pessach V; Tal Y
    Clin Exp Immunol; 2021 Oct; 206(1):56-67. PubMed ID: 34114647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Case report: Myocarditis in congenital STAT1 gain-of function.
    Staels F; Roosens W; Giovannozzi S; Moens L; Bogaert J; Iglesias-Herrero C; Gijsbers R; Bossuyt X; Frans G; Liston A; Humblet-Baron S; Meyts I; Van Aelst L; Schrijvers R
    Front Immunol; 2023; 14():1095595. PubMed ID: 37020552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ruxolitinib treatment of a patient with steroid-dependent severe autoimmunity due to STAT1 gain-of-function mutation.
    Moriya K; Suzuki T; Uchida N; Nakano T; Katayama S; Irie M; Rikiishi T; Niizuma H; Okada S; Imai K; Sasahara Y; Kure S
    Int J Hematol; 2020 Aug; 112(2):258-262. PubMed ID: 32180118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human STAT1 Gain-of-Function Heterozygous Mutations: Chronic Mucocutaneous Candidiasis and Type I Interferonopathy.
    Okada S; Asano T; Moriya K; Boisson-Dupuis S; Kobayashi M; Casanova JL; Puel A
    J Clin Immunol; 2020 Nov; 40(8):1065-1081. PubMed ID: 32852681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors.
    Borgström EW; Edvinsson M; Pérez LP; Norlin AC; Enoksson SL; Hansen S; Fasth A; Friman V; Kämpe O; Månsson R; Estupiñán HY; Wang Q; Ziyang T; Lakshmikanth T; Smith CIE; Brodin P; Bergman P
    J Clin Immunol; 2023 Jan; 43(1):136-150. PubMed ID: 36050429
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunoprofiling of monocytes in STAT1 gain-of-function chronic mucocutaneous candidiasis.
    Bloomfield M; Zentsova I; Milota T; Sediva A; Parackova Z
    Front Immunol; 2022; 13():983977. PubMed ID: 36172362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation.
    Weinacht KG; Charbonnier LM; Alroqi F; Plant A; Qiao Q; Wu H; Ma C; Torgerson TR; Rosenzweig SD; Fleisher TA; Notarangelo LD; Hanson IC; Forbes LR; Chatila TA
    J Allergy Clin Immunol; 2017 May; 139(5):1629-1640.e2. PubMed ID: 28139313
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Zimmerman O; Olbrich P; Freeman AF; Rosen LB; Uzel G; Zerbe CS; Rosenzweig SD; Kuehn HS; Holmes KL; Stephany D; Ding L; Sampaio EP; Hsu AP; Holland SM
    Front Immunol; 2019; 10():1433. PubMed ID: 31354696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.