208 related articles for article (PubMed ID: 35487932)
1. RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface.
Cho AR; Sul HJ; Kim YJ; Kim B; Zang DY
Sci Rep; 2022 Apr; 12(1):7013. PubMed ID: 35487932
[TBL] [Abstract][Full Text] [Related]
2. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
[TBL] [Abstract][Full Text] [Related]
3. The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
Yu J; Yusoff PAM; Woutersen DTJ; Goh P; Harmston N; Smits R; Epstein DM; Virshup DM; Madan B
Cancer Res; 2020 Dec; 80(24):5619-5632. PubMed ID: 33067269
[TBL] [Abstract][Full Text] [Related]
4. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling.
Tsukiyama T; Fukui A; Terai S; Fujioka Y; Shinada K; Takahashi H; Yamaguchi TP; Ohba Y; Hatakeyama S
Mol Cell Biol; 2015 Jun; 35(11):2007-23. PubMed ID: 25825523
[TBL] [Abstract][Full Text] [Related]
5. The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
Loregger A; Grandl M; Mejías-Luque R; Allgäuer M; Degenhart K; Haselmann V; Oikonomou C; Hatzis P; Janssen KP; Nitsche U; Gradl D; van den Broek O; Destree O; Ulm K; Neumaier M; Kalali B; Jung A; Varela I; Schmid RM; Rad R; Busch DH; Gerhard M
Sci Signal; 2015 Sep; 8(393):ra90. PubMed ID: 26350900
[TBL] [Abstract][Full Text] [Related]
6. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
[TBL] [Abstract][Full Text] [Related]
7. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
[TBL] [Abstract][Full Text] [Related]
8. Rnf43.
Serra S; Chetty R
J Clin Pathol; 2018 Jan; 71(1):1-6. PubMed ID: 29018044
[TBL] [Abstract][Full Text] [Related]
9. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.
Yamamoto D; Oshima H; Wang D; Takeda H; Kita K; Lei X; Nakayama M; Murakami K; Ohama T; Takemura H; Toyota M; Suzuki H; Inaki N; Oshima M
J Pathol; 2022 May; 257(1):39-52. PubMed ID: 35040131
[TBL] [Abstract][Full Text] [Related]
10. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.
Steinhart Z; Pavlovic Z; Chandrashekhar M; Hart T; Wang X; Zhang X; Robitaille M; Brown KR; Jaksani S; Overmeer R; Boj SF; Adams J; Pan J; Clevers H; Sidhu S; Moffat J; Angers S
Nat Med; 2017 Jan; 23(1):60-68. PubMed ID: 27869803
[TBL] [Abstract][Full Text] [Related]
11. The ubiquitin ligase RNF43 downregulation increases membrane expression of frizzled receptor in pancreatic ductal adenocarcinoma.
Wang D; Tan J; Xu Y; Han M; Tu Y; Zhu Z; Dou C; Xin J; Tan X; Zeng JP; Zhao G; Liu Z
Tumour Biol; 2016 Jan; 37(1):627-31. PubMed ID: 26240024
[TBL] [Abstract][Full Text] [Related]
12. Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
Li S; Lavrijsen M; Bakker A; Magierowski M; Magierowska K; Liu P; Wang W; Peppelenbosch MP; Smits R
Oncogene; 2020 Apr; 39(17):3458-3472. PubMed ID: 32103169
[TBL] [Abstract][Full Text] [Related]
13. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
Madan B; Walker MP; Young R; Quick L; Orgel KA; Ryan M; Gupta P; Henrich IC; Ferrer M; Marine S; Roberts BS; Arthur WT; Berndt JD; Oliveira AM; Moon RT; Virshup DM; Chou MM; Major MB
Proc Natl Acad Sci U S A; 2016 May; 113(21):E2945-54. PubMed ID: 27162353
[TBL] [Abstract][Full Text] [Related]
14. eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.
Thornton AM; Fang L; Lo A; McSharry M; Haan D; O'Brien C; Berger AH; Giannakis M; Brooks AN
PLoS Comput Biol; 2021 Jul; 17(7):e1009132. PubMed ID: 34214079
[TBL] [Abstract][Full Text] [Related]
15. Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
Takahashi N; Yamaguchi K; Ikenoue T; Fujii T; Furukawa Y
PLoS One; 2014; 9(1):e86582. PubMed ID: 24466159
[TBL] [Abstract][Full Text] [Related]
16. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.
Radaszkiewicz T; Bryja V
Cell Commun Signal; 2020 Jun; 18(1):91. PubMed ID: 32527265
[TBL] [Abstract][Full Text] [Related]
17. The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
Tu J; Park S; Yu W; Zhang S; Wu L; Carmon K; Liu QJ
Sci Rep; 2019 Dec; 9(1):18557. PubMed ID: 31811196
[TBL] [Abstract][Full Text] [Related]
18. RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
Spit M; Fenderico N; Jordens I; Radaszkiewicz T; Lindeboom RG; Bugter JM; Cristobal A; Ootes L; van Osch M; Janssen E; Boonekamp KE; Hanakova K; Potesil D; Zdrahal Z; Boj SF; Medema JP; Bryja V; Koo BK; Vermeulen M; Maurice MM
EMBO J; 2020 Sep; 39(18):e103932. PubMed ID: 32965059
[TBL] [Abstract][Full Text] [Related]
19. Issues with RNF43 antibodies to reliably detect intracellular location.
Li S; Zhang R; Lavrijsen M; van den Bosch TPP; Peppelenbosch MP; Smits R
PLoS One; 2023; 18(4):e0283894. PubMed ID: 37023034
[TBL] [Abstract][Full Text] [Related]
20. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Hao HX; Xie Y; Zhang Y; Charlat O; Oster E; Avello M; Lei H; Mickanin C; Liu D; Ruffner H; Mao X; Ma Q; Zamponi R; Bouwmeester T; Finan PM; Kirschner MW; Porter JA; Serluca FC; Cong F
Nature; 2012 Apr; 485(7397):195-200. PubMed ID: 22575959
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
