BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 35490781)

  • 1. Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks.
    Ruis K; Huynh O; Montales K; Barr NA; Michael WM
    J Biol Chem; 2022 Jul; 298(7):101992. PubMed ID: 35490781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.
    Bai L; Michael WM; Yan S
    Cell Signal; 2014 May; 26(5):857-67. PubMed ID: 24440306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-function analysis of TOPBP1's role in ATR signaling using the DSB-mediated ATR activation in Xenopus egg extracts (DMAX) system.
    Montales K; Kim A; Ruis K; Michael WM
    Sci Rep; 2021 Jan; 11(1):467. PubMed ID: 33432091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.
    Montales K; Ruis K; Lindsay H; Michael WM
    PLoS One; 2022; 17(8):e0271905. PubMed ID: 35917319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
    Ramírez-Lugo JS; Yoo HY; Yoon SJ; Dunphy WG
    Cell Cycle; 2011 Feb; 10(3):469-80. PubMed ID: 21263215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling.
    Zhang B; Wang E; Dai H; Shen J; Hsieh HJ; Lu X; Peng G
    J Biol Chem; 2014 Dec; 289(49):34284-95. PubMed ID: 25301947
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
    Duursma AM; Driscoll R; Elias JE; Cimprich KA
    Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.
    Lee J; Kumagai A; Dunphy WG
    J Biol Chem; 2007 Sep; 282(38):28036-44. PubMed ID: 17636252
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.
    Yamane K; Wu X; Chen J
    Mol Cell Biol; 2002 Jan; 22(2):555-66. PubMed ID: 11756551
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATR activation is regulated by dimerization of ATR activating proteins.
    Thada V; Cortez D
    J Biol Chem; 2021; 296():100455. PubMed ID: 33636182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
    Lindsey-Boltz LA; Sancar A
    J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    J Biol Chem; 2007 Jun; 282(24):17501-6. PubMed ID: 17446169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical analysis of TOPBP1 oligomerization.
    Kim A; Montales K; Ruis K; Senebandith H; Gasparyan H; Cowan Q; Michael WM
    DNA Repair (Amst); 2020 Dec; 96():102973. PubMed ID: 32987353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation.
    Thada V; Cortez D
    J Biol Chem; 2019 May; 294(21):8395-8402. PubMed ID: 30940728
    [TBL] [Abstract][Full Text] [Related]  

  • 16. STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication.
    Hong S; Cheng S; Iovane A; Laimins LA
    mBio; 2015 Dec; 6(6):e02006-15. PubMed ID: 26695634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
    Liu K; Graves JD; Lin FT; Lin WC
    J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.
    Ohashi E; Takeishi Y; Ueda S; Tsurimoto T
    DNA Repair (Amst); 2014 Sep; 21():1-11. PubMed ID: 25091155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates.
    Egger T; Morano L; Blanchard MP; Basbous J; Constantinou A
    Cell Rep; 2024 Apr; 43(4):114064. PubMed ID: 38578830
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Rad4(TopBP1) ATR-activation domain functions in G1/S phase in a chromatin-dependent manner.
    Lin SJ; Wardlaw CP; Morishita T; Miyabe I; Chahwan C; Caspari T; Schmidt U; Carr AM; Garcia V
    PLoS Genet; 2012 Jun; 8(6):e1002801. PubMed ID: 22761595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.