227 related articles for article (PubMed ID: 35495061)
1. TDP-43 Oligomerization and Phase Separation Properties Are Necessary for Autoregulation.
Koehler LC; Grese ZR; Bastos ACS; Mamede LD; Heyduk T; Ayala YM
Front Neurosci; 2022; 16():818655. PubMed ID: 35495061
[TBL] [Abstract][Full Text] [Related]
2. Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties.
Grese ZR; Bastos AC; Mamede LD; French RL; Miller TM; Ayala YM
EMBO Rep; 2021 Dec; 22(12):e53632. PubMed ID: 34787357
[TBL] [Abstract][Full Text] [Related]
3. Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
French RL; Grese ZR; Aligireddy H; Dhavale DD; Reeb AN; Kedia N; Kotzbauer PT; Bieschke J; Ayala YM
J Biol Chem; 2019 Apr; 294(17):6696-6709. PubMed ID: 30824544
[TBL] [Abstract][Full Text] [Related]
4. Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43
Zeng J; Tang Y; Dong X; Li F; Wei G
Proteins; 2023 Feb; ():. PubMed ID: 36841957
[TBL] [Abstract][Full Text] [Related]
5. TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
Li HR; Chiang WC; Chou PC; Wang WJ; Huang JR
J Biol Chem; 2018 Apr; 293(16):6090-6098. PubMed ID: 29511089
[TBL] [Abstract][Full Text] [Related]
6. A complex network of interdomain interactions underlies the conformational ensemble of monomeric TDP-43 and modulates its phase behavior.
Mohanty P; Rizuan A; Kim YC; Fawzi NL; Mittal J
Protein Sci; 2024 Feb; 33(2):e4891. PubMed ID: 38160320
[TBL] [Abstract][Full Text] [Related]
7. Molecular mechanisms of phase separation and amyloidosis of ALS/FTD-linked FUS and TDP-43.
Song J
Aging Dis; 2023 Nov; ():. PubMed ID: 38029395
[TBL] [Abstract][Full Text] [Related]
8. ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Conicella AE; Zerze GH; Mittal J; Fawzi NL
Structure; 2016 Sep; 24(9):1537-49. PubMed ID: 27545621
[TBL] [Abstract][Full Text] [Related]
9. Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders.
Naskar A; Nayak A; Salaikumaran MR; Vishal SS; Gopal PP
Front Mol Neurosci; 2023; 16():1242925. PubMed ID: 37720552
[TBL] [Abstract][Full Text] [Related]
10. Granulins modulate liquid-liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43.
Bhopatkar AA; Uversky VN; Rangachari V
J Biol Chem; 2020 Feb; 295(8):2506-2519. PubMed ID: 31911437
[TBL] [Abstract][Full Text] [Related]
11. Sequence Determinants of TDP-43 Ribonucleoprotein Condensate Formation and Axonal Transport in Neurons.
Vishal SS; Wijegunawardana D; Salaikumaran MR; Gopal PP
Front Cell Dev Biol; 2022; 10():876893. PubMed ID: 35646935
[TBL] [Abstract][Full Text] [Related]
12. Molecular mechanisms linking loss of TDP-43 function to amyotrophic lateral sclerosis/frontotemporal dementia-related genes.
Koike Y
Neurosci Res; 2024 May; ():. PubMed ID: 38723906
[TBL] [Abstract][Full Text] [Related]
13. Liquid-Liquid Phase Separation of TDP-43 and FUS in Physiology and Pathology of Neurodegenerative Diseases.
Carey JL; Guo L
Front Mol Biosci; 2022; 9():826719. PubMed ID: 35187086
[TBL] [Abstract][Full Text] [Related]
14. TDP-43 pathology: From noxious assembly to therapeutic removal.
Keating SS; San Gil R; Swanson MEV; Scotter EL; Walker AK
Prog Neurobiol; 2022 Apr; 211():102229. PubMed ID: 35101542
[TBL] [Abstract][Full Text] [Related]
15. Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-43
Girdhar A; Bharathi V; Tiwari VR; Abhishek S; Deeksha W; Mahawar US; Raju G; Singh SK; Prabusankar G; Rajakumara E; Patel BK
Int J Biol Macromol; 2020 Mar; 147():117-130. PubMed ID: 31917988
[TBL] [Abstract][Full Text] [Related]
16. Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
Gruijs da Silva LA; Simonetti F; Hutten S; Riemenschneider H; Sternburg EL; Pietrek LM; Gebel J; Dötsch V; Edbauer D; Hummer G; Stelzl LS; Dormann D
EMBO J; 2022 Apr; 41(8):e108443. PubMed ID: 35112738
[TBL] [Abstract][Full Text] [Related]
17. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
[TBL] [Abstract][Full Text] [Related]
18. The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain.
Babinchak WM; Haider R; Dumm BK; Sarkar P; Surewicz K; Choi JK; Surewicz WK
J Biol Chem; 2019 Apr; 294(16):6306-6317. PubMed ID: 30814253
[TBL] [Abstract][Full Text] [Related]
19. Altered Phase Separation and Cellular Impact in
Solomon DA; Smikle R; Reid MJ; Mizielinska S
Front Cell Neurosci; 2021; 15():664151. PubMed ID: 33967699
[TBL] [Abstract][Full Text] [Related]
20. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Mackenzie IR; Nicholson AM; Sarkar M; Messing J; Purice MD; Pottier C; Annu K; Baker M; Perkerson RB; Kurti A; Matchett BJ; Mittag T; Temirov J; Hsiung GR; Krieger C; Murray ME; Kato M; Fryer JD; Petrucelli L; Zinman L; Weintraub S; Mesulam M; Keith J; Zivkovic SA; Hirsch-Reinshagen V; Roos RP; Züchner S; Graff-Radford NR; Petersen RC; Caselli RJ; Wszolek ZK; Finger E; Lippa C; Lacomis D; Stewart H; Dickson DW; Kim HJ; Rogaeva E; Bigio E; Boylan KB; Taylor JP; Rademakers R
Neuron; 2017 Aug; 95(4):808-816.e9. PubMed ID: 28817800
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]