These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. A cytosolic heat shock protein 90 and co-chaperone p23 complex activates RIPK3/MLKL during necroptosis of endothelial cells in acute respiratory distress syndrome. Yu X; Mao M; Liu X; Shen T; Li T; Yu H; Zhang J; Chen X; Zhao X; Zhu D J Mol Med (Berl); 2020 Apr; 98(4):569-583. PubMed ID: 32072232 [TBL] [Abstract][Full Text] [Related]
5. Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Hildebrand JM; Tanzer MC; Lucet IS; Young SN; Spall SK; Sharma P; Pierotti C; Garnier JM; Dobson RC; Webb AI; Tripaydonis A; Babon JJ; Mulcair MD; Scanlon MJ; Alexander WS; Wilks AF; Czabotar PE; Lessene G; Murphy JM; Silke J Proc Natl Acad Sci U S A; 2014 Oct; 111(42):15072-7. PubMed ID: 25288762 [TBL] [Abstract][Full Text] [Related]
6. Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop. Tanzer MC; Tripaydonis A; Webb AI; Young SN; Varghese LN; Hall C; Alexander WS; Hildebrand JM; Silke J; Murphy JM Biochem J; 2015 Oct; 471(2):255-65. PubMed ID: 26283547 [TBL] [Abstract][Full Text] [Related]
9. Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis. Rodriguez DA; Weinlich R; Brown S; Guy C; Fitzgerald P; Dillon CP; Oberst A; Quarato G; Low J; Cripps JG; Chen T; Green DR Cell Death Differ; 2016 Jan; 23(1):76-88. PubMed ID: 26024392 [TBL] [Abstract][Full Text] [Related]
10. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. Wang Z; Feng J; Yu J; Chen G J Cell Sci; 2019 May; 132(10):. PubMed ID: 31028177 [TBL] [Abstract][Full Text] [Related]
11. MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis. Zhou T; DeRoo E; Yang H; Stranz A; Wang Q; Ginnan R; Singer HA; Liu B Cells; 2021 Sep; 10(9):. PubMed ID: 34572045 [TBL] [Abstract][Full Text] [Related]
12. Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies. Petrie EJ; Birkinshaw RW; Koide A; Denbaum E; Hildebrand JM; Garnish SE; Davies KA; Sandow JJ; Samson AL; Gavin X; Fitzgibbon C; Young SN; Hennessy PJ; Smith PPC; Webb AI; Czabotar PE; Koide S; Murphy JM Proc Natl Acad Sci U S A; 2020 Apr; 117(15):8468-8475. PubMed ID: 32234780 [TBL] [Abstract][Full Text] [Related]
13. Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. Li W; Ni H; Wu S; Han S; Chen C; Li L; Li Y; Gui F; Han J; Deng X FEBS Lett; 2020 Jul; 594(14):2294-2302. PubMed ID: 32412649 [TBL] [Abstract][Full Text] [Related]
14. RIPK1 inhibits ZBP1-driven necroptosis during development. Newton K; Wickliffe KE; Maltzman A; Dugger DL; Strasser A; Pham VC; Lill JR; Roose-Girma M; Warming S; Solon M; Ngu H; Webster JD; Dixit VM Nature; 2016 Dec; 540(7631):129-133. PubMed ID: 27819682 [TBL] [Abstract][Full Text] [Related]
15. The NS1 Protein of Influenza A Virus Participates in Necroptosis by Interacting with MLKL and Increasing Its Oligomerization and Membrane Translocation. Gaba A; Xu F; Lu Y; Park HS; Liu G; Zhou Y J Virol; 2019 Jan; 93(2):. PubMed ID: 30355688 [TBL] [Abstract][Full Text] [Related]
16. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Lin J; Kumari S; Kim C; Van TM; Wachsmuth L; Polykratis A; Pasparakis M Nature; 2016 Dec; 540(7631):124-128. PubMed ID: 27819681 [TBL] [Abstract][Full Text] [Related]
17. Necroptosis: a crucial pathogenic mediator of human disease. Choi ME; Price DR; Ryter SW; Choi AMK JCI Insight; 2019 Aug; 4(15):. PubMed ID: 31391333 [TBL] [Abstract][Full Text] [Related]
18. ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis. Ma B; Marcotte D; Paramasivam M; Michelsen K; Wang T; Bertolotti-Ciarlet A; Jones JH; Moree B; Butko M; Salafsky J; Sun X; McKee T; Silvian LF PLoS One; 2016; 11(11):e0165983. PubMed ID: 27832137 [TBL] [Abstract][Full Text] [Related]
19. The Structural Basis of Necroptotic Cell Death Signaling. Petrie EJ; Czabotar PE; Murphy JM Trends Biochem Sci; 2019 Jan; 44(1):53-63. PubMed ID: 30509860 [TBL] [Abstract][Full Text] [Related]