BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 35534113)

  • 1. Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface.
    Thirumal Kumar D; Udhaya Kumar S; Jain N; Sowmya B; Balsekar K; Siva R; Kamaraj B; Sidenna M; George Priya Doss C; Zayed H
    Adv Protein Chem Struct Biol; 2022; 130():375-397. PubMed ID: 35534113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular dynamics simulations reveal the effect of mutations in the RING domains of BRCA1-BARD1 complex and its relevance to the prognosis of breast cancer.
    Kiewhuo K; Priyadarsinee L; Sarma H; Sastry GN
    J Biomol Struct Dyn; 2023; 41(22):12734-12752. PubMed ID: 36775657
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
    Stewart MD; Zelin E; Dhall A; Walsh T; Upadhyay E; Corn JE; Chatterjee C; King MC; Klevit RE
    Proc Natl Acad Sci U S A; 2018 Feb; 115(6):1316-1321. PubMed ID: 29367421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
    Dizin E; Irminger-Finger I
    Int J Biochem Cell Biol; 2010 May; 42(5):693-700. PubMed ID: 20060929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The BRCA1/BARD1 ubiquitin ligase and its substrates.
    Witus SR; Stewart MD; Klevit RE
    Biochem J; 2021 Sep; 478(18):3467-3483. PubMed ID: 34591954
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico investigation on the mutational analysis of BRCA1-BARD1 RING domains and its effect on nucleosome recognition and ubiquitination.
    Sarma H; Kiewhuo K; Jamir E; Sastry GN
    Biophys Chem; 2023 Sep; 300():107070. PubMed ID: 37339533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
    Brzovic PS; Rajagopal P; Hoyt DW; King MC; Klevit RE
    Nat Struct Biol; 2001 Oct; 8(10):833-7. PubMed ID: 11573085
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
    Hashizume R; Fukuda M; Maeda I; Nishikawa H; Oyake D; Yabuki Y; Ogata H; Ohta T
    J Biol Chem; 2001 May; 276(18):14537-40. PubMed ID: 11278247
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
    Zhao W; Steinfeld JB; Liang F; Chen X; Maranon DG; Jian Ma C; Kwon Y; Rao T; Wang W; Sheng C; Song X; Deng Y; Jimenez-Sainz J; Lu L; Jensen RB; Xiong Y; Kupfer GM; Wiese C; Greene EC; Sung P
    Nature; 2017 Oct; 550(7676):360-365. PubMed ID: 28976962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks.
    Lee C; Banerjee T; Gillespie J; Ceravolo A; Parvinsmith MR; Starita LM; Fields S; Toland AE; Parvin JD
    Hum Mutat; 2015 Dec; 36(12):1205-14. PubMed ID: 26350354
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
    Laufer M; Nandula SV; Modi AP; Wang S; Jasin M; Murty VV; Ludwig T; Baer R
    J Biol Chem; 2007 Nov; 282(47):34325-33. PubMed ID: 17848578
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.
    Stewart MD; Duncan ED; Coronado E; DaRosa PA; Pruneda JN; Brzovic PS; Klevit RE
    Protein Sci; 2017 Mar; 26(3):475-483. PubMed ID: 27977889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility.
    Morris JR; Pangon L; Boutell C; Katagiri T; Keep NH; Solomon E
    Hum Mol Genet; 2006 Feb; 15(4):599-606. PubMed ID: 16403807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.
    Meza JE; Brzovic PS; King MC; Klevit RE
    J Biol Chem; 1999 Feb; 274(9):5659-65. PubMed ID: 10026184
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination.
    Zhu Q; Huang J; Huang H; Li H; Yi P; Kloeber JA; Yuan J; Chen Y; Deng M; Luo K; Gao M; Guo G; Tu X; Yin P; Zhang Y; Su J; Chen J; Lou Z
    Nat Commun; 2021 Nov; 12(1):6653. PubMed ID: 34789768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase.
    Nishikawa H; Ooka S; Sato K; Arima K; Okamoto J; Klevit RE; Fukuda M; Ohta T
    J Biol Chem; 2004 Feb; 279(6):3916-24. PubMed ID: 14638690
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BRCA1 and BARD1 colocalize mainly in the cytoplasm of breast cancer tumors, and their isoforms show differential expression.
    Wiener D; Gajardo-Meneses P; Ortega-Hernández V; Herrera-Cares C; Díaz S; Fernández W; Cornejo V; Gamboa J; Tapia T; Alvarez C; Carvallo P
    Breast Cancer Res Treat; 2015 Oct; 153(3):669-78. PubMed ID: 26395808
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of novel alternatively spliced BRCA1-associated RING domain (BARD1) messenger RNAs in human peripheral blood lymphocytes and in sporadic breast cancer tissues.
    Lombardi G; Falaschi E; Di Cristofano C; Naccarato AG; Sensi E; Aretini P; Roncella M; Bevilacqua G; Caligo MA
    Genes Chromosomes Cancer; 2007 Sep; 46(9):791-5. PubMed ID: 17497650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations.
    Ghimenti C; Sensi E; Presciuttini S; Brunetti IM; Conte P; Bevilacqua G; Caligo MA
    Genes Chromosomes Cancer; 2002 Mar; 33(3):235-42. PubMed ID: 11807980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.
    Eakin CM; Maccoss MJ; Finney GL; Klevit RE
    Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5794-9. PubMed ID: 17392432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.