168 related articles for article (PubMed ID: 35540679)
1.
Zhang J; Ren L; Wang Y; Fang X
RSC Adv; 2019 Nov; 9(67):39338-39347. PubMed ID: 35540679
[TBL] [Abstract][Full Text] [Related]
2. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient.
Quancard J; Klein T; Fung SY; Renatus M; Hughes N; Israël L; Priatel JJ; Kang S; Blank MA; Viner RI; Blank J; Schlapbach A; Erbel P; Kizhakkedathu J; Villard F; Hersperger R; Turvey SE; Eder J; Bornancin F; Overall CM
Nat Chem Biol; 2019 Mar; 15(3):304-313. PubMed ID: 30692685
[TBL] [Abstract][Full Text] [Related]
3. Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors.
Schiesser S; Hajek P; Pople HE; Käck H; Öster L; Cox RJ
Eur J Med Chem; 2022 Jan; 227():113925. PubMed ID: 34742013
[TBL] [Abstract][Full Text] [Related]
4. Autocleavage of the paracaspase MALT1 at Arg-781 attenuates NF-κB signaling and regulates the growth of activated B-cell like diffuse large B-cell lymphoma cells.
Wu CH; Yang YH; Chen MR; Tsai CH; Cheng AL; Doong SL
PLoS One; 2018; 13(6):e0199779. PubMed ID: 29953499
[TBL] [Abstract][Full Text] [Related]
5. A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis.
Dumont C; Sivars U; Andreasson T; Odqvist L; Mattsson J; DeMicco A; Pardali K; Johansson G; Yrlid L; Cox RJ; Seeliger F; Larsson M; Gehrmann U; Davis AM; Vaarala O
PLoS One; 2020; 15(9):e0222548. PubMed ID: 32870913
[TBL] [Abstract][Full Text] [Related]
6. MALT1--a universal soldier: multiple strategies to ensure NF-κB activation and target gene expression.
Afonina IS; Elton L; Carpentier I; Beyaert R
FEBS J; 2015 Sep; 282(17):3286-97. PubMed ID: 25996250
[TBL] [Abstract][Full Text] [Related]
7. Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease.
Lu T; Connolly PJ; Philippar U; Sun W; Cummings MD; Barbay K; Gys L; Van Nuffel L; Austin N; Bekkers M; Shen F; Cai A; Attar R; Meerpoel L; Edwards J
Bioorg Med Chem Lett; 2019 Dec; 29(23):126743. PubMed ID: 31678006
[TBL] [Abstract][Full Text] [Related]
8. MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation.
Liu W; Guo W; Hang N; Yang Y; Wu X; Shen Y; Cao J; Sun Y; Xu Q
Oncotarget; 2016 May; 7(21):30536-49. PubMed ID: 27105502
[TBL] [Abstract][Full Text] [Related]
9. The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.
Varfolomeev E; Wayson SM; Dixit VM; Fairbrother WJ; Vucic D
J Biol Chem; 2006 Sep; 281(39):29022-9. PubMed ID: 16891304
[TBL] [Abstract][Full Text] [Related]
10. Probes to monitor activity of the paracaspase MALT1.
Hachmann J; Edgington-Mitchell LE; Poreba M; Sanman LE; Drag M; Bogyo M; Salvesen GS
Chem Biol; 2015 Jan; 22(1):139-47. PubMed ID: 25556944
[TBL] [Abstract][Full Text] [Related]
11. MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling.
Elton L; Carpentier I; Staal J; Driege Y; Haegman M; Beyaert R
FEBS J; 2016 Feb; 283(3):403-12. PubMed ID: 26573773
[TBL] [Abstract][Full Text] [Related]
12. MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-κB activation.
Liu X; Yue C; Shi L; Liu G; Cao Q; Shan Q; Wang Y; Chen X; Li H; Wang J; Gao S; Niu M; Yu R
J Cell Mol Med; 2020 Jul; 24(13):7550-7562. PubMed ID: 32452133
[TBL] [Abstract][Full Text] [Related]
13. Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma.
Liang X; Sun C; Li C; Yu H; Wei X; Liu X; Bao W; Shi Y; Sun X; Khamrakulov M; Yang C; Liu H
J Med Chem; 2021 Jul; 64(13):9217-9237. PubMed ID: 34181850
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells.
Ferch U; Kloo B; Gewies A; Pfänder V; Düwel M; Peschel C; Krappmann D; Ruland J
J Exp Med; 2009 Oct; 206(11):2313-20. PubMed ID: 19841089
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationship studies of 3-substituted pyrazoles as novel allosteric inhibitors of MALT1 protease.
Asaba KN; Adachi Y; Tokumaru K; Watanabe A; Goto Y; Aoki T
Bioorg Med Chem Lett; 2021 Jun; 41():127996. PubMed ID: 33775836
[TBL] [Abstract][Full Text] [Related]
16. MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness.
Fung SY; Lu HY; Sharma M; Sharma AA; Saferali A; Jia A; Abraham L; Klein T; Gold MR; Noterangelo LD; Overall CM; Turvey SE
Front Immunol; 2021; 12():749794. PubMed ID: 34721419
[TBL] [Abstract][Full Text] [Related]
17. MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation.
Che T; You Y; Wang D; Tanner MJ; Dixit VM; Lin X
J Biol Chem; 2004 Apr; 279(16):15870-6. PubMed ID: 14754896
[TBL] [Abstract][Full Text] [Related]
18. A patent review of MALT1 inhibitors (2013-present).
Hamp I; O'Neill TJ; Plettenburg O; Krappmann D
Expert Opin Ther Pat; 2021 Dec; 31(12):1079-1096. PubMed ID: 34214002
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis.
Mc Guire C; Elton L; Wieghofer P; Staal J; Voet S; Demeyer A; Nagel D; Krappmann D; Prinz M; Beyaert R; van Loo G
J Neuroinflammation; 2014 Jul; 11():124. PubMed ID: 25043939
[TBL] [Abstract][Full Text] [Related]
20. T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20.
Coornaert B; Baens M; Heyninck K; Bekaert T; Haegman M; Staal J; Sun L; Chen ZJ; Marynen P; Beyaert R
Nat Immunol; 2008 Mar; 9(3):263-71. PubMed ID: 18223652
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
